SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pd2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 2pd2 HYPOTHETICAL PROTEIN
ST0148
(Sulfurisphaera
tokodaii) 		5 / 9 ALA A  16
LEU A 106
ILE A  95
HIS A  37
LEU A  36
 None
 1.46A 1ereA-2pd2A:
undetectable		 1ereA-2pd2A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 2pd2 HYPOTHETICAL PROTEIN
ST0148
(Sulfurisphaera
tokodaii) 		5 / 9 ALA A  16
LEU A 106
ILE A  95
HIS A  37
LEU A  36
 None
 1.48A 1ereC-2pd2A:
undetectable		 1ereC-2pd2A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 2pd2 HYPOTHETICAL PROTEIN
ST0148
(Sulfurisphaera
tokodaii) 		5 / 9 ALA A  16
LEU A 106
ILE A  95
HIS A  37
LEU A  36
 None
 1.46A 1ereD-2pd2A:
undetectable		 1ereD-2pd2A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 2pd2 HYPOTHETICAL PROTEIN
ST0148
(Sulfurisphaera
tokodaii) 		5 / 11 LEU A  36
VAL A  34
ILE A  64
LEU A  45
LEU A  81
 None
 1.34A 1mrqA-2pd2A:
2.5		 1mrqA-2pd2A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 2pd2 HYPOTHETICAL PROTEIN
ST0148
(Sulfurisphaera
tokodaii) 		5 / 12 VAL A   4
LEU A  44
GLU A 101
VAL A  13
LEU A  17
 None
 0.99A 4y0qA-2pd2A:
undetectable		 4y0qA-2pd2A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 2pd2 HYPOTHETICAL PROTEIN
ST0148
(Sulfurisphaera
tokodaii) 		5 / 12 ARG A  51
PHE A  10
ILE A  82
ILE A  85
ILE A   7
 None
 1.08A 5hw8B-2pd2A:
undetectable
5hw8F-2pd2A:
undetectable
5hw8G-2pd2A:
undetectable		 5hw8B-2pd2A:
19.05
5hw8F-2pd2A:
19.05
5hw8G-2pd2A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2pd2 HYPOTHETICAL PROTEIN
ST0148
(Sulfurisphaera
tokodaii) 		5 / 8 VAL A  13
LEU A  17
ILE A  54
ILE A  85
SER A  70
 None
 1.45A 5numA-2pd2A:
undetectable		 5numA-2pd2A:
23.42