SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2peb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 2peb PUTATIVE DIOXYGENASE
(Nostoc
punctiforme) 		4 / 8 PHE A  44
HIS A  14
HIS A  84
HIS A  12
 None
ZN  A 200 ( 3.1A)
ZN  A 200 ( 3.4A)
ZN  A 200 ( 3.1A)
 0.97A 1azmA-2pebA:
undetectable		 1azmA-2pebA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 2peb PUTATIVE DIOXYGENASE
(Nostoc
punctiforme) 		4 / 8 PHE A  44
HIS A  14
HIS A  84
HIS A  12
 None
ZN  A 200 ( 3.1A)
ZN  A 200 ( 3.4A)
ZN  A 200 ( 3.1A)
 0.95A 1bzmA-2pebA:
undetectable		 1bzmA-2pebA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 2peb PUTATIVE DIOXYGENASE
(Nostoc
punctiforme) 		5 / 11 HIS A  51
GLY A  49
GLU A 110
HIS A  94
LEU A 112
 UNL  A 201 (-4.0A)
None
None
UNL  A 201 (-3.9A)
None
 1.38A 1mjqA-2pebA:
undetectable
1mjqB-2pebA:
undetectable		 1mjqA-2pebA:
17.19
1mjqB-2pebA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_H_SAMH200_0
(METHIONINE REPRESSOR)		 2peb PUTATIVE DIOXYGENASE
(Nostoc
punctiforme) 		5 / 10 HIS A  51
GLY A  49
GLU A 110
HIS A  94
LEU A 112
 UNL  A 201 (-4.0A)
None
None
UNL  A 201 (-3.9A)
None
 1.38A 1mjqG-2pebA:
undetectable
1mjqH-2pebA:
undetectable		 1mjqG-2pebA:
17.19
1mjqH-2pebA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)		 2peb PUTATIVE DIOXYGENASE
(Nostoc
punctiforme) 		3 / 3 HIS A  14
HIS A  84
HIS A  12
 ZN  A 200 ( 3.1A)
ZN  A 200 ( 3.4A)
ZN  A 200 ( 3.1A)
 0.64A 1rkyA-2pebA:
undetectable		 1rkyA-2pebA:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 2peb PUTATIVE DIOXYGENASE
(Nostoc
punctiforme) 		4 / 4 HIS A  12
GLU A  86
HIS A  84
HIS A  14
 ZN  A 200 ( 3.1A)
ZN  A 200 ( 4.8A)
ZN  A 200 ( 3.4A)
ZN  A 200 ( 3.1A)
 1.31A 1uttA-2pebA:
undetectable		 1uttA-2pebA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 2peb PUTATIVE DIOXYGENASE
(Nostoc
punctiforme) 		3 / 3 HIS A  14
HIS A  84
HIS A  12
 ZN  A 200 ( 3.1A)
ZN  A 200 ( 3.4A)
ZN  A 200 ( 3.1A)
 0.70A 1w2zD-2pebA:
undetectable		 1w2zD-2pebA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UYQ_A_SAMA1311_0
(HYPOTHETICAL PROTEIN
ML2640)		 2peb PUTATIVE DIOXYGENASE
(Nostoc
punctiforme) 		5 / 7 ALA A  90
GLY A  88
ASP A  93
LEU A 112
ARG A 113
 None
 1.42A 2uyqA-2pebA:
undetectable		 2uyqA-2pebA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 2peb PUTATIVE DIOXYGENASE
(Nostoc
punctiforme) 		4 / 6 LEU A  32
SER A  21
PHE A  17
ASP A  18
 None
PG4  A 202 (-2.8A)
None
PG4  A 202 (-2.8A)
 1.25A 2vn1B-2pebA:
undetectable		 2vn1B-2pebA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 2peb PUTATIVE DIOXYGENASE
(Nostoc
punctiforme) 		3 / 3 HIS A  14
HIS A  84
HIS A  12
 ZN  A 200 ( 3.1A)
ZN  A 200 ( 3.4A)
ZN  A 200 ( 3.1A)
 0.74A 3hiiA-2pebA:
undetectable		 3hiiA-2pebA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 2peb PUTATIVE DIOXYGENASE
(Nostoc
punctiforme) 		3 / 3 HIS A  14
HIS A  84
HIS A  12
 ZN  A 200 ( 3.1A)
ZN  A 200 ( 3.4A)
ZN  A 200 ( 3.1A)
 0.72A 3hiiB-2pebA:
undetectable		 3hiiB-2pebA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 2peb PUTATIVE DIOXYGENASE
(Nostoc
punctiforme) 		3 / 3 HIS A  51
HIS A  14
HIS A  84
 UNL  A 201 (-4.0A)
ZN  A 200 ( 3.1A)
ZN  A 200 ( 3.4A)
 0.99A 5oexA-2pebA:
undetectable		 5oexA-2pebA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 2peb PUTATIVE DIOXYGENASE
(Nostoc
punctiforme) 		5 / 10 ARG A  29
VAL A  28
ALA A  25
LEU A  32
LEU A  72
 None
 0.88A 6f5uA-2pebA:
undetectable
6f5uB-2pebA:
0.0		 6f5uA-2pebA:
24.17
6f5uB-2pebA:
26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 2peb PUTATIVE DIOXYGENASE
(Nostoc
punctiforme) 		6 / 10 ARG A  29
VAL A  28
ALA A  25
LEU A  32
LEU A  40
LEU A  72
 None
 1.13A 6f6nA-2pebA:
undetectable
6f6nB-2pebA:
undetectable		 6f6nA-2pebA:
24.17
6f6nB-2pebA:
26.23