SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2peg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 2peg HEMOGLOBIN SUBUNIT
BETA
(Trematomus
bernacchii) 		4 / 8 LEU B  71
THR B  84
LEU B  88
ALA B 140
 None
None
HEM  B 400 ( 4.8A)
None
 0.90A 1fiqC-2pegB:
undetectable		 1fiqC-2pegB:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 2peg HEMOGLOBIN SUBUNIT
BETA
(Trematomus
bernacchii) 		4 / 5 PHE B  42
LEU B  96
VAL B  98
VAL B  67
 HEM  B 400 (-4.6A)
HEM  B 400 (-4.2A)
HEM  B 400 ( 4.5A)
HEM  B 400 (-3.7A)
 1.20A 1t88B-2pegB:
undetectable		 1t88B-2pegB:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2peg HEMOGLOBIN SUBUNIT
BETA
(Trematomus
bernacchii) 		4 / 5 PHE B  42
LEU B  96
VAL B  98
VAL B  67
 HEM  B 400 (-4.6A)
HEM  B 400 (-4.2A)
HEM  B 400 ( 4.5A)
HEM  B 400 (-3.7A)
 1.23A 2m56A-2pegB:
undetectable		 2m56A-2pegB:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ4_X_DXCX75_0
(CYTOCHROME C7)		 2peg HEMOGLOBIN SUBUNIT
BETA
(Trematomus
bernacchii) 		5 / 9 ILE B 110
LEU B 134
PHE B 133
MET B  78
GLY B  74
 None
 1.32A 3sj4X-2pegB:
undetectable		 3sj4X-2pegB:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2peg HEMOGLOBIN SUBUNIT
BETA
(Trematomus
bernacchii) 		6 / 12 VAL B 113
VAL B 138
PHE B 130
VAL B  67
LEU B  71
VAL B 137
 None
None
None
HEM  B 400 (-3.7A)
None
None
 1.40A 3w68D-2pegB:
undetectable		 3w68D-2pegB:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 2peg HEMOGLOBIN SUBUNIT
BETA
(Trematomus
bernacchii) 		5 / 7 ILE B 110
LEU B 134
PHE B 133
MET B  78
GLY B  74
 None
 1.42A 4hajA-2pegB:
undetectable		 4hajA-2pegB:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 2peg HEMOGLOBIN SUBUNIT
BETA
(Trematomus
bernacchii) 		5 / 8 ILE B 110
LEU B 134
PHE B 133
MET B  78
GLY B  74
 None
 1.38A 4hb8A-2pegB:
undetectable		 4hb8A-2pegB:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2peg HEMOGLOBIN SUBUNIT
BETA
(Trematomus
bernacchii) 		4 / 5 PHE B  42
LEU B  96
VAL B  98
VAL B  67
 HEM  B 400 (-4.6A)
HEM  B 400 (-4.2A)
HEM  B 400 ( 4.5A)
HEM  B 400 (-3.7A)
 1.21A 4l49A-2pegB:
undetectable		 4l49A-2pegB:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_B_9TPB601_1
(SERUM ALBUMIN)		 2peg HEMOGLOBIN SUBUNIT
BETA
(Trematomus
bernacchii) 		5 / 12 ALA B 116
ILE B  11
LEU B  68
LEU B  71
GLY B  74
 None
 1.15A 4l9qB-2pegB:
2.2		 4l9qB-2pegB:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 2peg HEMOGLOBIN SUBUNIT
BETA
(Trematomus
bernacchii) 		4 / 6 ILE B  81
MET B  78
ASN B  77
ASP B  79
 None
 1.42A 6dhbA-2pegB:
undetectable		 6dhbA-2pegB:
20.55