SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pej'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 2pej ORF134
(Synechococcus
sp.
PCC
7002) 		5 / 11 VAL A  90
LEU A  86
LEU A  14
THR A  10
THR A  13
 None
 0.93A 1dmyA-2pejA:
undetectable		 1dmyA-2pejA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 2pej ORF134
(Synechococcus
sp.
PCC
7002) 		5 / 12 VAL A  90
LEU A  86
LEU A  14
THR A  10
THR A  13
 None
 1.00A 2aw1A-2pejA:
undetectable		 2aw1A-2pejA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 2pej ORF134
(Synechococcus
sp.
PCC
7002) 		5 / 10 LEU A  86
VAL A  90
LEU A  14
THR A  10
THR A  13
 None
 1.06A 4e3hA-2pejA:
undetectable		 4e3hA-2pejA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 2pej ORF134
(Synechococcus
sp.
PCC
7002) 		5 / 10 VAL A  90
LEU A  86
LEU A  14
THR A  10
THR A  13
 None
 1.03A 4e3hA-2pejA:
undetectable		 4e3hA-2pejA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 2pej ORF134
(Synechococcus
sp.
PCC
7002) 		5 / 12 VAL A  90
LEU A  86
LEU A  14
THR A  10
THR A  13
 None
 0.96A 4m2wA-2pejA:
undetectable		 4m2wA-2pejA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 2pej ORF134
(Synechococcus
sp.
PCC
7002) 		5 / 12 VAL A  90
LEU A  86
LEU A  14
THR A  10
THR A  13
 None
 0.93A 4xiwG-2pejA:
undetectable		 4xiwG-2pejA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 2pej ORF134
(Synechococcus
sp.
PCC
7002) 		5 / 12 GLN A  37
ALA A  38
GLU A  63
LEU A  67
ILE A  71
 None
 1.28A 5vlmG-2pejA:
undetectable		 5vlmG-2pejA:
20.90