SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pfk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		4 / 5 LEU A  28
THR A  29
ARG A  54
VAL A  57
 None
 0.93A 1ekjF-2pfkA:
2.4
1ekjG-2pfkA:
undetectable		 1ekjF-2pfkA:
20.12
1ekjG-2pfkA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		4 / 8 LEU A 122
VAL A  23
TYR A 270
GLY A  22
 None
 1.04A 1jlfA-2pfkA:
undetectable
1jlfB-2pfkA:
undetectable		 1jlfA-2pfkA:
21.10
1jlfB-2pfkA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		5 / 11 THR A 136
ALA A 179
GLY A 138
THR A 141
ALA A 142
 None
 1.16A 2f16H-2pfkA:
undetectable
2f16I-2pfkA:
undetectable		 2f16H-2pfkA:
22.40
2f16I-2pfkA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		5 / 11 THR A 136
ALA A 179
GLY A 138
THR A 141
ALA A 142
 None
 1.16A 2f16V-2pfkA:
undetectable
2f16W-2pfkA:
undetectable		 2f16V-2pfkA:
22.40
2f16W-2pfkA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		6 / 12 LEU A 122
GLY A  15
ASP A  12
VAL A  57
VAL A  98
ILE A 100
 None
 1.08A 2f8gB-2pfkA:
undetectable		 2f8gB-2pfkA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		5 / 9 THR A 113
GLY A 280
LEU A 275
LEU A 122
LEU A 112
 None
 1.28A 2npnA-2pfkA:
2.5		 2npnA-2pfkA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		3 / 3 LEU A 122
PRO A 123
ARG A 266
 None
 0.54A 2qd4B-2pfkA:
undetectable		 2qd4B-2pfkA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3V_A_TOPA1169_1
(DIHYDROFOLATE
REDUCTASE)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		5 / 12 ALA A 180
ILE A 150
LEU A 247
SER A 164
ILE A 220
 None
 1.10A 2w3vA-2pfkA:
undetectable		 2w3vA-2pfkA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		4 / 7 VAL A 202
LYS A 206
ILE A 209
GLY A 212
 None
 0.61A 3bjwF-2pfkA:
undetectable		 3bjwF-2pfkA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		4 / 7 VAL A 202
LYS A 206
ILE A 209
GLY A 212
 None
 0.77A 3bjwH-2pfkA:
undetectable		 3bjwH-2pfkA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		4 / 6 ILE A  81
TYR A  41
MET A 115
ILE A  86
 None
 1.21A 3eteA-2pfkA:
2.8
3eteE-2pfkA:
2.7		 3eteA-2pfkA:
20.91
3eteE-2pfkA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		4 / 5 ILE A  81
TYR A  41
MET A 115
ILE A  86
 None
 1.23A 3eteB-2pfkA:
2.7
3eteC-2pfkA:
2.8		 3eteB-2pfkA:
20.91
3eteC-2pfkA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB201_1
(PROTEIN S100-A4)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		4 / 8 GLY A 101
ILE A 296
PHE A 117
PHE A  76
 None
 0.95A 3ko0B-2pfkA:
undetectable
3ko0J-2pfkA:
undetectable		 3ko0B-2pfkA:
14.20
3ko0J-2pfkA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		4 / 8 GLY A 101
ILE A 296
PHE A 117
PHE A  76
 None
 1.03A 3ko0K-2pfkA:
undetectable
3ko0S-2pfkA:
undetectable		 3ko0K-2pfkA:
14.20
3ko0S-2pfkA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		5 / 11 THR A 136
ALA A 179
GLY A 138
THR A 141
ALA A 142
 None
 1.14A 3mg0V-2pfkA:
undetectable
3mg0W-2pfkA:
undetectable		 3mg0V-2pfkA:
22.40
3mg0W-2pfkA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_1
(PROTEASE)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		5 / 12 GLY A 138
ASP A 127
GLY A 101
ILE A 100
ALA A 264
 None
 0.97A 3n3iA-2pfkA:
undetectable		 3n3iA-2pfkA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ4_X_DXCX75_0
(CYTOCHROME C7)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		5 / 9 ILE A 234
LEU A 201
ILE A 217
PHE A 188
GLY A 208
 None
 1.36A 3sj4X-2pfkA:
undetectable		 3sj4X-2pfkA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		5 / 12 GLY A 254
ILE A 100
GLY A 138
ALA A  18
ALA A  19
 None
 1.02A 3sueA-2pfkA:
undetectable		 3sueA-2pfkA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		4 / 5 THR A 133
ILE A 286
GLU A 289
PHE A 140
 None
 1.50A 4acbC-2pfkA:
4.4		 4acbC-2pfkA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_A_RKEA401_1
(PROTON-GATED ION
CHANNEL)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		4 / 8 ASP A  53
VAL A  24
PHE A  67
LEU A  68
 None
 1.07A 4f8hA-2pfkA:
undetectable
4f8hB-2pfkA:
undetectable		 4f8hA-2pfkA:
21.64
4f8hB-2pfkA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_B_RKEB401_1
(PROTON-GATED ION
CHANNEL)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		4 / 8 ASP A  53
VAL A  24
PHE A  67
LEU A  68
 None
 1.03A 4f8hB-2pfkA:
undetectable
4f8hC-2pfkA:
undetectable		 4f8hB-2pfkA:
21.64
4f8hC-2pfkA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_C_RKEC401_1
(PROTON-GATED ION
CHANNEL)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		4 / 8 ASP A  53
VAL A  24
PHE A  67
LEU A  68
 None
 1.05A 4f8hC-2pfkA:
undetectable
4f8hD-2pfkA:
undetectable		 4f8hC-2pfkA:
21.64
4f8hD-2pfkA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_D_RKED401_1
(PROTON-GATED ION
CHANNEL)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		4 / 8 ASP A  53
VAL A  24
PHE A  67
LEU A  68
 None
 1.06A 4f8hD-2pfkA:
undetectable
4f8hE-2pfkA:
undetectable		 4f8hD-2pfkA:
21.64
4f8hE-2pfkA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_E_RKEE401_1
(PROTON-GATED ION
CHANNEL)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		4 / 8 VAL A  24
PHE A  67
LEU A  68
ASP A  53
 None
 1.06A 4f8hA-2pfkA:
undetectable
4f8hE-2pfkA:
undetectable		 4f8hA-2pfkA:
21.64
4f8hE-2pfkA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		4 / 6 GLY A 185
GLY A 184
GLU A 187
ILE A 217
 None
 0.90A 4fglD-2pfkA:
4.7		 4fglD-2pfkA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		5 / 8 ILE A 234
LEU A 201
ILE A 217
PHE A 188
GLY A 208
 None
 1.34A 4hb8A-2pfkA:
undetectable		 4hb8A-2pfkA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA501_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		5 / 12 ILE A 137
ASP A 260
THR A 145
ILE A 126
GLU A 222
 None
 1.32A 4i41A-2pfkA:
undetectable		 4i41A-2pfkA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		4 / 8 ILE A 272
ALA A  19
VAL A  98
VAL A  34
 None
 0.82A 4jltA-2pfkA:
undetectable		 4jltA-2pfkA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMU_C_RFPC1401_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		5 / 12 HIS A 249
ARG A 252
LEU A 176
PRO A  14
ILE A 126
 None
 1.28A 4kmuC-2pfkA:
undetectable		 4kmuC-2pfkA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		5 / 9 ALA A  19
ALA A  18
GLY A 101
GLY A 124
ASP A 260
 None
 1.16A 4qwuK-2pfkA:
undetectable
4qwuL-2pfkA:
undetectable		 4qwuK-2pfkA:
24.71
4qwuL-2pfkA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		5 / 12 THR A   8
GLY A  11
GLY A  10
ALA A 142
THR A 145
 None
 1.14A 4uckB-2pfkA:
undetectable		 4uckB-2pfkA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		5 / 12 ALA A  13
GLY A  15
GLY A 254
SER A 255
GLY A 124
 None
 1.01A 5gwxA-2pfkA:
undetectable		 5gwxA-2pfkA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		5 / 11 LEU A  68
GLY A  15
ILE A  20
ASN A  17
VAL A  23
 None
 1.38A 5hjiA-2pfkA:
undetectable		 5hjiA-2pfkA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		3 / 3 ALA A  85
ASN A  88
LEU A  89
 None
 0.50A 5i1oA-2pfkA:
undetectable		 5i1oA-2pfkA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		3 / 3 ALA A  85
ASN A  88
LEU A  89
 None
 0.48A 5i1pD-2pfkA:
undetectable		 5i1pD-2pfkA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		4 / 7 GLY A  22
VAL A  98
ILE A   4
VAL A   6
 None
 0.81A 5ik1A-2pfkA:
undetectable		 5ik1A-2pfkA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		5 / 12 VAL A  23
ALA A  18
VAL A   6
GLY A   5
ILE A   4
 None
 0.81A 5j2tC-2pfkA:
undetectable		 5j2tC-2pfkA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		5 / 12 GLY A  15
PRO A 123
GLY A 124
ASN A  17
ASP A 260
 None
 1.33A 5yn6A-2pfkA:
undetectable		 5yn6A-2pfkA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNI_A_SAMA401_0
(NSP16 PROTEIN)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		5 / 12 GLY A  15
PRO A 123
GLY A 124
ASN A  17
ASP A 260
 None
 1.35A 5yniA-2pfkA:
undetectable		 5yniA-2pfkA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_B_SAMB505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		5 / 12 GLY A 268
ILE A 137
TYR A 106
CYH A 119
GLY A 101
 None
 1.10A 6bp4B-2pfkA:
undetectable		 6bp4B-2pfkA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		5 / 12 GLY A 254
ILE A 100
GLY A 138
ALA A  18
ALA A  19
 None
 1.03A 6c2mD-2pfkA:
undetectable		 6c2mD-2pfkA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		5 / 11 ALA A  19
ALA A  18
GLY A 101
GLY A 124
ASP A 260
 None
 0.86A 6hwdK-2pfkA:
undetectable
6hwdL-2pfkA:
undetectable		 6hwdK-2pfkA:
13.55
6hwdL-2pfkA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2pfk 6-PHOSPHOFRUCTOKINAS
E ISOZYME I
(Escherichia
coli) 		5 / 11 ALA A  19
ALA A  18
GLY A 101
GLY A 124
ASP A 260
 None
 0.87A 6hwdY-2pfkA:
undetectable
6hwdZ-2pfkA:
undetectable		 6hwdY-2pfkA:
13.55
6hwdZ-2pfkA:
12.81