SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pfx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 2pfx UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 6 ASP A 159
ILE A 160
LEU A 147
GLU A  71
 None
 1.00A 2ya7B-2pfxA:
undetectable		 2ya7B-2pfxA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 2pfx UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 6 ASP A 159
ILE A 160
LEU A 147
GLU A  71
 None
 1.00A 2ya7D-2pfxA:
undetectable		 2ya7D-2pfxA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 2pfx UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 8 GLU A 141
ARG A 148
ARG A 144
ASP A 154
 None
 0.86A 3mjrD-2pfxA:
undetectable		 3mjrD-2pfxA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)		 2pfx UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 8 PHE A 166
PHE A  53
ASN A 171
ALA A 174
 None
 0.94A 3t3sF-2pfxA:
undetectable		 3t3sF-2pfxA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2pfx UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Ruegeria
sp.
TM1040) 		3 / 3 PHE A 167
CYH A  88
HIS A  92
 None
 1.22A 3u9fF-2pfxA:
undetectable		 3u9fF-2pfxA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2pfx UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Ruegeria
sp.
TM1040) 		3 / 3 PHE A 167
CYH A  88
HIS A  92
 None
 1.33A 3u9fL-2pfxA:
undetectable		 3u9fL-2pfxA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2pfx UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Ruegeria
sp.
TM1040) 		3 / 3 PHE A 167
CYH A  88
HIS A  92
 None
 1.22A 3u9fS-2pfxA:
undetectable		 3u9fS-2pfxA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 2pfx UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 6 SER A  65
GLU A  64
ARG A 148
GLY A 151
 None
 0.95A 5cdpA-2pfxA:
undetectable
5cdpB-2pfxA:
undetectable		 5cdpA-2pfxA:
18.98
5cdpB-2pfxA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 2pfx UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 7 HIS A  92
LEU A  40
TYR A 185
VAL A  39
 None
 0.96A 6g2pA-2pfxA:
undetectable		 6g2pA-2pfxA:
18.54