SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pg3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)		 2pg3 QUEUOSINE
BIOSYNTHESIS PROTEIN
QUEC
(Pectobacterium
atrosepticum) 		4 / 6 TYR A  25
GLU A 157
PRO A 159
VAL A   6
 None
 1.40A 1q13A-2pg3A:
undetectable		 1q13A-2pg3A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 2pg3 QUEUOSINE
BIOSYNTHESIS PROTEIN
QUEC
(Pectobacterium
atrosepticum) 		3 / 3 GLY A 191
GLU A  42
ASN A 190
 None
 0.60A 1zq9A-2pg3A:
3.0		 1zq9A-2pg3A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2pg3 QUEUOSINE
BIOSYNTHESIS PROTEIN
QUEC
(Pectobacterium
atrosepticum) 		3 / 3 LYS A 227
ASP A 127
ASN A 164
 None
 0.99A 2bm9A-2pg3A:
2.2		 2bm9A-2pg3A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2pg3 QUEUOSINE
BIOSYNTHESIS PROTEIN
QUEC
(Pectobacterium
atrosepticum) 		4 / 7 THR A 158
VAL A 119
THR A 121
VAL A   7
 None
 0.62A 3em0B-2pg3A:
undetectable		 3em0B-2pg3A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2pg3 QUEUOSINE
BIOSYNTHESIS PROTEIN
QUEC
(Pectobacterium
atrosepticum) 		3 / 3 ALA A 172
TYR A 175
PRO A 159
 None
 0.56A 4zdyA-2pg3A:
undetectable		 4zdyA-2pg3A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5INZ_D_DVAD15_0
(THETA DEFENSIN-2,
D-PEPTIDE
THETA DEFENSIN-2,
L-PEPTIDE)		 2pg3 QUEUOSINE
BIOSYNTHESIS PROTEIN
QUEC
(Pectobacterium
atrosepticum) 		3 / 3 GLY A 198
CYH A 203
CYH A 200
 ZN  A 300 ( 4.9A)
ZN  A 300 (-2.3A)
ZN  A 300 (-2.3A)
 0.91A 5inzB-2pg3A:
undetectable		 5inzB-2pg3A:
5.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)		 2pg3 QUEUOSINE
BIOSYNTHESIS PROTEIN
QUEC
(Pectobacterium
atrosepticum) 		4 / 8 THR A 105
ILE A 146
ALA A 145
LEU A 142
 None
 0.78A 5te8B-2pg3A:
undetectable		 5te8B-2pg3A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_1
(STIE PROTEIN)		 2pg3 QUEUOSINE
BIOSYNTHESIS PROTEIN
QUEC
(Pectobacterium
atrosepticum) 		4 / 5 THR A 185
ARG A 206
GLN A 177
ASP A  24
 None
 1.40A 6ectA-2pg3A:
undetectable		 6ectA-2pg3A:
25.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_1
(STIE PROTEIN)		 2pg3 QUEUOSINE
BIOSYNTHESIS PROTEIN
QUEC
(Pectobacterium
atrosepticum) 		4 / 5 THR A 185
ARG A 206
GLN A 177
ASP A  24
 None
 1.36A 6ecxA-2pg3A:
1.8		 6ecxA-2pg3A:
25.70