SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ph0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)
2ph0 UNCHARACTERIZED
PROTEIN

(Pectobacterium
carotovorum)
4 / 8 PHE A 126
HIS A  66
LEU A  17
THR A  16
None
0.92A 1azmA-2ph0A:
undetectable
1azmA-2ph0A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)
2ph0 UNCHARACTERIZED
PROTEIN

(Pectobacterium
carotovorum)
4 / 8 PHE A 126
HIS A  66
LEU A  17
THR A  16
None
0.93A 1bzmA-2ph0A:
undetectable
1bzmA-2ph0A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)
2ph0 UNCHARACTERIZED
PROTEIN

(Pectobacterium
carotovorum)
4 / 7 SER A 122
PHE A 154
VAL A 124
ALA A 158
None
1.09A 1fo4B-2ph0A:
undetectable
1fo4B-2ph0A:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))
2ph0 UNCHARACTERIZED
PROTEIN

(Pectobacterium
carotovorum)
5 / 12 PHE A 137
VAL A  32
ARG A 113
GLY A  15
LEU A 146
None
1.18A 2cbrA-2ph0A:
undetectable
2cbrA-2ph0A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)
2ph0 UNCHARACTERIZED
PROTEIN

(Pectobacterium
carotovorum)
4 / 8 ILE A  71
LYS A 135
ILE A  64
GLU A  18
None
0.58A 2j9dJ-2ph0A:
undetectable
2j9dK-2ph0A:
undetectable
2j9dL-2ph0A:
undetectable
2j9dJ-2ph0A:
21.05
2j9dK-2ph0A:
21.05
2j9dL-2ph0A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_CHDA332_0
(CHOLOYLGLYCINE
HYDROLASE)
2ph0 UNCHARACTERIZED
PROTEIN

(Pectobacterium
carotovorum)
5 / 12 ILE A  64
PHE A 137
PHE A 110
ILE A 108
LEU A  28
None
1.00A 2rlcA-2ph0A:
undetectable
2rlcA-2ph0A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)
2ph0 UNCHARACTERIZED
PROTEIN

(Pectobacterium
carotovorum)
6 / 12 PHE A 126
ILE A 108
ILE A 136
ILE A  64
ALA A 109
VAL A  51
None
1.47A 3fpjA-2ph0A:
undetectable
3fpjA-2ph0A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)
2ph0 UNCHARACTERIZED
PROTEIN

(Pectobacterium
carotovorum)
4 / 5 THR A  67
HIS A  66
ALA A  68
ASP A  69
None
1.26A 5mfxA-2ph0A:
undetectable
5mfxA-2ph0A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)
2ph0 UNCHARACTERIZED
PROTEIN

(Pectobacterium
carotovorum)
4 / 6 ASP A  46
GLN A  50
LEU A 157
PHE A 110
None
0.93A 6ekuA-2ph0A:
2.0
6ekuA-2ph0A:
14.74