SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ph1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 2ph1 NUCLEOTIDE-BINDING
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 7 THR A 180
GLU A 178
THR A 182
VAL A 158
 None
 1.12A 1tv8A-2ph1A:
2.8		 1tv8A-2ph1A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 2ph1 NUCLEOTIDE-BINDING
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 7 THR A 180
GLU A 178
THR A 182
VAL A 158
 None
 1.07A 1tv8B-2ph1A:
2.8		 1tv8B-2ph1A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2ph1 NUCLEOTIDE-BINDING
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 10 GLY A  51
LEU A 133
LEU A  53
ILE A 134
ILE A  62
 None
 1.11A 2f8dB-2ph1A:
undetectable		 2f8dB-2ph1A:
26.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 2ph1 NUCLEOTIDE-BINDING
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 8 THR A 180
GLU A 178
THR A 182
VAL A 158
 None
 1.16A 2fb2A-2ph1A:
2.8		 2fb2A-2ph1A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 2ph1 NUCLEOTIDE-BINDING
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 7 THR A 180
GLU A 178
THR A 182
VAL A 158
 None
 1.10A 2fb2B-2ph1A:
3.1		 2fb2B-2ph1A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 2ph1 NUCLEOTIDE-BINDING
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 12 GLY A  26
GLY A  29
THR A  36
LEU A 133
VAL A 157
 None
 0.76A 2oxtA-2ph1A:
undetectable		 2oxtA-2ph1A:
25.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_2
(PHOSPHOLIPASE A2)		 2ph1 NUCLEOTIDE-BINDING
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 9 VAL A 184
VAL A 157
GLY A 155
PRO A 153
THR A 180
 None
 1.25A 3bjwG-2ph1A:
undetectable		 3bjwG-2ph1A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_1
(PHOSPHOLIPASE A2)		 2ph1 NUCLEOTIDE-BINDING
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 10 VAL A 184
VAL A 157
GLY A 155
PRO A 153
THR A 180
 None
 1.26A 3bjwD-2ph1A:
undetectable		 3bjwD-2ph1A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 2ph1 NUCLEOTIDE-BINDING
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 8 ILE A  62
ILE A  90
PHE A  66
VAL A  23
 None
 0.87A 3ua5A-2ph1A:
undetectable		 3ua5A-2ph1A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_2
(HIV-1 PROTEASE)		 2ph1 NUCLEOTIDE-BINDING
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 8 ALA A  55
ASP A  56
ASP A 135
PRO A 153
 None
 0.84A 4eyrB-2ph1A:
undetectable		 4eyrB-2ph1A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 2ph1 NUCLEOTIDE-BINDING
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 8 ILE A 226
LEU A  38
LYS A 234
ILE A 233
 None
 0.71A 4hb8A-2ph1A:
undetectable		 4hb8A-2ph1A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 2ph1 NUCLEOTIDE-BINDING
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 8 SER A  25
GLU A 164
VAL A  35
THR A  34
 None
 0.96A 4lnwA-2ph1A:
undetectable		 4lnwA-2ph1A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 2ph1 NUCLEOTIDE-BINDING
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 6 SER A  25
GLU A 164
VAL A  35
THR A  34
 None
 0.94A 4lnxA-2ph1A:
undetectable		 4lnxA-2ph1A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 2ph1 NUCLEOTIDE-BINDING
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 6 SER A 160
GLU A 164
VAL A  35
THR A  36
 None
 1.39A 4lnxA-2ph1A:
undetectable		 4lnxA-2ph1A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2ph1 NUCLEOTIDE-BINDING
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 4 LEU A 165
LEU A 187
SER A 213
ALA A 215
 None
 1.13A 5uunA-2ph1A:
undetectable		 5uunA-2ph1A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 2ph1 NUCLEOTIDE-BINDING
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 8 LEU A  38
TYR A 244
GLU A 229
THR A  34
 None
 1.23A 6c71B-2ph1A:
undetectable		 6c71B-2ph1A:
16.38