SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ph4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 2ph4 ZHAOERMIATOXIN
(Protobothrops
mangshanensis) 		5 / 7 GLY A  30
HIS A  48
TYR A  52
PRO A  68
LYS A  69
 PEG  A 401 ( 4.5A)
PEG  A 401 ( 4.9A)
None
None
None
 0.67A 1th6A-2ph4A:
19.4		 1th6A-2ph4A:
55.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 2ph4 ZHAOERMIATOXIN
(Protobothrops
mangshanensis) 		5 / 12 GLY A  30
TYR A  52
PRO A  68
LYS A  69
LYS A  70
 PEG  A 401 ( 4.5A)
None
None
None
None
 1.09A 1y4lA-2ph4A:
22.4		 1y4lA-2ph4A:
74.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 2ph4 ZHAOERMIATOXIN
(Protobothrops
mangshanensis) 		5 / 12 LEU A   2
GLY A  30
TYR A  52
PRO A  68
LYS A  70
 None
PEG  A 401 ( 4.5A)
None
None
None
 0.60A 1y4lA-2ph4A:
22.4		 1y4lA-2ph4A:
74.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Y4L_B_SVRB301_2
(PHOSPHOLIPASE A2
HOMOLOG 2)		 2ph4 ZHAOERMIATOXIN
(Protobothrops
mangshanensis) 		5 / 11 LEU A   2
LEU A   5
VAL A  31
HIS A  48
TYR A  52
 None
PEG  A 401 ( 4.3A)
SO4  A 301 ( 3.6A)
PEG  A 401 ( 4.9A)
None
 1.05A 1y4lB-2ph4A:
23.1		 1y4lB-2ph4A:
74.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Y4L_B_SVRB301_2
(PHOSPHOLIPASE A2
HOMOLOG 2)		 2ph4 ZHAOERMIATOXIN
(Protobothrops
mangshanensis) 		5 / 11 LEU A   5
VAL A  31
HIS A  48
TYR A  52
LYS A  70
 PEG  A 401 ( 4.3A)
SO4  A 301 ( 3.6A)
PEG  A 401 ( 4.9A)
None
None
 0.70A 1y4lB-2ph4A:
23.1		 1y4lB-2ph4A:
74.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2ph4 ZHAOERMIATOXIN
(Protobothrops
mangshanensis) 		5 / 7 GLY A  30
HIS A  48
TYR A  52
PRO A  68
LYS A  69
 PEG  A 401 ( 4.5A)
PEG  A 401 ( 4.9A)
None
None
None
 0.66A 2armA-2ph4A:
19.4		 2armA-2ph4A:
55.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 2ph4 ZHAOERMIATOXIN
(Protobothrops
mangshanensis) 		5 / 7 LYS A   7
GLN A  11
GLY A  15
ARG A 107
LEU A 110
 None
 1.12A 3bjwB-2ph4A:
19.4		 3bjwB-2ph4A:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 2ph4 ZHAOERMIATOXIN
(Protobothrops
mangshanensis) 		5 / 6 LYS A   7
GLN A  11
GLY A  15
ARG A 107
LEU A 110
 None
 1.29A 3bjwE-2ph4A:
19.1		 3bjwE-2ph4A:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 2ph4 ZHAOERMIATOXIN
(Protobothrops
mangshanensis) 		5 / 7 LYS A   7
GLN A  11
GLY A  15
ARG A 107
LEU A 110
 None
 1.25A 3bjwF-2ph4A:
19.4		 3bjwF-2ph4A:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 2ph4 ZHAOERMIATOXIN
(Protobothrops
mangshanensis) 		4 / 7 GLN A  11
GLY A  15
ARG A 107
LEU A 110
 None
 0.50A 3bjwH-2ph4A:
19.3		 3bjwH-2ph4A:
57.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2F_A_ADNA601_1
(5'-NUCLEOTIDASE)		 2ph4 ZHAOERMIATOXIN
(Protobothrops
mangshanensis) 		5 / 9 ARG A  33
ASN A  28
GLY A  35
GLY A  26
ASP A  42
 None
 1.45A 4h2fA-2ph4A:
undetectable		 4h2fA-2ph4A:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2G_A_ADNA603_1
(5'-NUCLEOTIDASE)		 2ph4 ZHAOERMIATOXIN
(Protobothrops
mangshanensis) 		5 / 9 ARG A  33
ASN A  28
GLY A  35
GLY A  26
ASP A  42
 None
 1.34A 4h2gA-2ph4A:
undetectable		 4h2gA-2ph4A:
11.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CE2_B_SVRB202_2
(-)		 2ph4 ZHAOERMIATOXIN
(Protobothrops
mangshanensis) 		6 / 12 LEU A   2
LEU A   5
GLY A  30
GLY A  32
PRO A  68
LYS A  69
 None
PEG  A 401 ( 4.3A)
PEG  A 401 ( 4.5A)
SO4  A 301 (-3.5A)
None
None
 1.22A 6ce2B-2ph4A:
21.2		 6ce2B-2ph4A:
72.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CE2_B_SVRB202_2
(-)		 2ph4 ZHAOERMIATOXIN
(Protobothrops
mangshanensis) 		6 / 12 LEU A   2
LEU A   5
GLY A  30
TYR A  52
PRO A  68
LYS A  69
 None
PEG  A 401 ( 4.3A)
PEG  A 401 ( 4.5A)
None
None
None
 0.81A 6ce2B-2ph4A:
21.2		 6ce2B-2ph4A:
72.73