SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ph7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 2ph7 UNCHARACTERIZED
PROTEIN AF_2093
(Archaeoglobus
fulgidus) 		4 / 6 LEU A 196
ILE A 208
TYR A 214
VAL A 171
 None
 1.13A 1db1A-2ph7A:
undetectable		 1db1A-2ph7A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_1
(ADENOSYLHOMOCYSTEINA
SE)		 2ph7 UNCHARACTERIZED
PROTEIN AF_2093
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 196
HIS A 156
GLU A 162
LEU A  33
GLY A  37
 None
 1.17A 1xwfA-2ph7A:
undetectable		 1xwfA-2ph7A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_1
(ADENOSYLHOMOCYSTEINA
SE)		 2ph7 UNCHARACTERIZED
PROTEIN AF_2093
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 196
HIS A 156
GLU A 162
LEU A  33
GLY A  37
 None
 1.20A 1xwfC-2ph7A:
undetectable		 1xwfC-2ph7A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_1
(ADENOSYLHOMOCYSTEINA
SE)		 2ph7 UNCHARACTERIZED
PROTEIN AF_2093
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 196
HIS A 156
GLU A 162
LEU A  33
GLY A  37
 None
 1.20A 1xwfD-2ph7A:
undetectable		 1xwfD-2ph7A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_A_LNRA200_1
(D7R4 PROTEIN)		 2ph7 UNCHARACTERIZED
PROTEIN AF_2093
(Archaeoglobus
fulgidus) 		5 / 12 ARG A  25
TYR A 128
ILE A   5
VAL A  51
GLU A  49
 None
 1.14A 2qeoA-2ph7A:
undetectable		 2qeoA-2ph7A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2ph7 UNCHARACTERIZED
PROTEIN AF_2093
(Archaeoglobus
fulgidus) 		4 / 5 VAL A 201
PHE A 180
ILE A 198
PHE A 183
 None
 0.76A 3owxB-2ph7A:
2.4		 3owxB-2ph7A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 2ph7 UNCHARACTERIZED
PROTEIN AF_2093
(Archaeoglobus
fulgidus) 		4 / 7 ILE A  24
VAL A   6
LEU A   9
SER A  10
 None
 0.52A 3r9vA-2ph7A:
undetectable
3r9vB-2ph7A:
undetectable		 3r9vA-2ph7A:
22.80
3r9vB-2ph7A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_C_QMRC1214_1
(CAPITELLA TELETA
ACHBP)		 2ph7 UNCHARACTERIZED
PROTEIN AF_2093
(Archaeoglobus
fulgidus) 		4 / 8 VAL A 168
TYR A 167
ILE A 170
ILE A 198
 None
 1.05A 4afgD-2ph7A:
undetectable
4afgE-2ph7A:
undetectable		 4afgD-2ph7A:
20.51
4afgE-2ph7A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2ph7 UNCHARACTERIZED
PROTEIN AF_2093
(Archaeoglobus
fulgidus) 		4 / 8 VAL A 168
TRP A 199
ILE A 208
LEU A 220
 None
 0.87A 4jq1B-2ph7A:
undetectable		 4jq1B-2ph7A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 2ph7 UNCHARACTERIZED
PROTEIN AF_2093
(Archaeoglobus
fulgidus) 		4 / 7 TYR A 139
ARG A 130
ILE A 170
ALA A 141
 None
 0.87A 4lv9A-2ph7A:
undetectable		 4lv9A-2ph7A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 2ph7 UNCHARACTERIZED
PROTEIN AF_2093
(Archaeoglobus
fulgidus) 		5 / 7 PRO A 203
VAL A 201
PHE A 118
VAL A 114
ILE A 110
 None
 1.42A 5bmvC-2ph7A:
undetectable		 5bmvC-2ph7A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)		 2ph7 UNCHARACTERIZED
PROTEIN AF_2093
(Archaeoglobus
fulgidus) 		5 / 11 ALA A 191
ALA A 194
VAL A 160
LEU A 157
HIS A 156
 None
 1.21A 5eb5A-2ph7A:
undetectable		 5eb5A-2ph7A:
18.90