SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2phl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHF_A_FOLA187_0
(DIHYDROFOLATE
REDUCTASE)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		5 / 12 ILE A 131
GLN A 110
THR A 319
ILE A 241
LEU A  75
 None
 1.12A 1dhfA-2phlA:
undetectable		 1dhfA-2phlA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHF_B_FOLB187_0
(DIHYDROFOLATE
REDUCTASE)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		5 / 12 ILE A 131
GLN A 110
THR A 319
ILE A 241
LEU A  75
 None
 1.07A 1dhfB-2phlA:
undetectable		 1dhfB-2phlA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1URM_A_BEZA201_0
(PEROXIREDOXIN 5)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		5 / 9 THR A 319
SER A 243
LEU A  75
PHE A 321
ARG A 232
 None
 1.48A 1urmA-2phlA:
undetectable		 1urmA-2phlA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA602_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		4 / 8 LEU A 129
ILE A 131
LEU A  85
ILE A  84
 None
 0.92A 2azxA-2phlA:
undetectable		 2azxA-2phlA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		3 / 3 PHE A  14
ASN A  12
PHE A 300
 None
 0.99A 2zbuD-2phlA:
undetectable		 2zbuD-2phlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		4 / 5 GLN A  68
ILE A 192
LEU A  65
PHE A 118
 None
 1.11A 3ls4L-2phlA:
2.1		 3ls4L-2phlA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		3 / 3 TYR A  96
TYR A 119
GLU A 202
 None
 0.95A 3pfgA-2phlA:
undetectable		 3pfgA-2phlA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		3 / 4 SER A  43
GLY A 277
GLU A 286
 None
 0.68A 3raeA-2phlA:
undetectable
3raeC-2phlA:
undetectable		 3raeA-2phlA:
22.20
3raeC-2phlA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		3 / 3 ASN A 328
ALA A 325
LYS A 259
 None
 0.94A 3runA-2phlA:
undetectable		 3runA-2phlA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		6 / 12 LEU A  54
ILE A 263
LEU A 275
PHE A  39
ILE A 261
ALA A 304
 None
 1.36A 3uwlB-2phlA:
undetectable		 3uwlB-2phlA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		3 / 3 PHE A 146
VAL A  55
ILE A  33
 None
 0.55A 4emaA-2phlA:
undetectable		 4emaA-2phlA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KEB_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		5 / 12 ILE A 131
GLN A 110
THR A 319
ILE A 241
LEU A  75
 None
 0.98A 4kebB-2phlA:
undetectable		 4kebB-2phlA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_A_REAA602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		5 / 12 ILE A 369
GLY A 345
ARG A 346
PHE A 358
LEU A 354
 None
 1.24A 5fhzA-2phlA:
undetectable		 5fhzA-2phlA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		3 / 3 VAL A 253
LEU A 354
MET A 366
 None
 0.83A 5ikrA-2phlA:
undetectable		 5ikrA-2phlA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		5 / 12 ILE A 263
LEU A 275
PHE A  39
ILE A 261
ALA A 304
 None
 1.26A 5j7wC-2phlA:
undetectable		 5j7wC-2phlA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_ACTA305_0
(CARBONIC ANHYDRASE 4)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		4 / 4 GLN A 133
VAL A  55
GLU A 145
ILE A 143
 None
 1.48A 5jncA-2phlA:
0.0		 5jncA-2phlA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		3 / 3 SER A 258
TYR A 257
TYR A 256
 None
 0.87A 5lakC-2phlA:
undetectable
5lakJ-2phlA:
undetectable		 5lakC-2phlA:
22.36
5lakJ-2phlA:
1.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJD_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		5 / 9 LEU A  87
LEU A  99
ILE A  33
ILE A 112
LEU A  65
 None
 1.37A 5ljdA-2phlA:
undetectable		 5ljdA-2phlA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA810_1
(CATALASE-PEROXIDASE)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		4 / 6 ARG A 291
HIS A 272
LEU A 251
PRO A 254
 None
 1.26A 5syjA-2phlA:
undetectable		 5syjA-2phlA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB810_1
(CATALASE-PEROXIDASE)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		4 / 6 ARG A 291
HIS A 272
LEU A 251
PRO A 254
 None
 1.31A 5syjB-2phlA:
undetectable		 5syjB-2phlA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		5 / 12 SER A 314
ALA A 250
PHE A 318
LEU A 264
VAL A 266
 None
 1.14A 5tudA-2phlA:
undetectable		 5tudA-2phlA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		6 / 12 SER A 314
ALA A 250
PHE A 318
VAL A 308
LEU A 264
VAL A 266
 None
 1.42A 5tudD-2phlA:
undetectable		 5tudD-2phlA:
19.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CB4_A_BEZA501_0
(CANAVALIN)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		4 / 8 HIS A 255
VAL A 262
LEU A 264
ILE A 302
 None
 0.36A 6cb4A-2phlA:
41.1		 6cb4A-2phlA:
44.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		5 / 12 LEU A  54
ILE A 263
LEU A 275
PHE A  39
ILE A 261
 None
 1.07A 6qxsB-2phlA:
undetectable		 6qxsB-2phlA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QYA_B_FOZB401_0
(THYMIDYLATE SYNTHASE)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		6 / 12 LEU A  54
ILE A 263
LEU A 275
PHE A  39
ILE A 261
ALA A 304
 None
 1.32A 6qyaB-2phlA:
undetectable		 6qyaB-2phlA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QYA_D_FOZD401_0
(THYMIDYLATE SYNTHASE)		 2phl PHASEOLIN
(Phaseolus
vulgaris) 		6 / 12 LEU A  54
ILE A 263
LEU A 275
PHE A  39
ILE A 261
ALA A 304
 None
 1.34A 6qyaD-2phlA:
undetectable		 6qyaD-2phlA:
20.64