SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pig'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 2pig PUTATIVE TRANSFERASE
(Salmonella
enterica) 		3 / 3 ARG A 131
ILE A  98
TRP A  97
 None
 1.07A 1m8eB-2pigA:
undetectable		 1m8eB-2pigA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_2
(CYTOCHROME P450 2C8)		 2pig PUTATIVE TRANSFERASE
(Salmonella
enterica) 		4 / 8 ILE A 109
ASN A 161
VAL A 160
ALA A 130
 None
 0.65A 2nniA-2pigA:
undetectable		 2nniA-2pigA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 2pig PUTATIVE TRANSFERASE
(Salmonella
enterica) 		4 / 7 ASP A  37
VAL A  38
ALA A  31
TRP A  60
 None
 1.00A 2q6oA-2pigA:
undetectable		 2q6oA-2pigA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2pig PUTATIVE TRANSFERASE
(Salmonella
enterica) 		3 / 3 ARG A 131
ILE A  98
TRP A  97
 None
 1.03A 3e68A-2pigA:
undetectable		 3e68A-2pigA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2pig PUTATIVE TRANSFERASE
(Salmonella
enterica) 		3 / 3 ARG A 131
ILE A  98
TRP A  97
 None
 1.07A 3e6tB-2pigA:
undetectable		 3e6tB-2pigA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_A_KANA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2pig PUTATIVE TRANSFERASE
(Salmonella
enterica) 		5 / 11 ASN A 201
GLU A 137
SER A 136
HIS A 162
ASN A 134
 None
 1.43A 3kp5A-2pigA:
undetectable		 3kp5A-2pigA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_A_KANA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2pig PUTATIVE TRANSFERASE
(Salmonella
enterica) 		5 / 11 ASN A 201
GLU A 137
SER A 136
HIS A 162
ASN A 161
 None
 1.38A 3kp5A-2pigA:
undetectable		 3kp5A-2pigA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_A_KANA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2pig PUTATIVE TRANSFERASE
(Salmonella
enterica) 		5 / 11 VAL A 202
GLU A 137
SER A 136
HIS A 162
ASN A 161
 None
 1.49A 3kp5A-2pigA:
undetectable		 3kp5A-2pigA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_2
(PROTEASE)		 2pig PUTATIVE TRANSFERASE
(Salmonella
enterica) 		5 / 9 ARG A 121
ALA A 101
ASP A  99
ILE A  80
ILE A 103
 None
 1.07A 3ndwB-2pigA:
undetectable		 3ndwB-2pigA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 2pig PUTATIVE TRANSFERASE
(Salmonella
enterica) 		5 / 12 PRO A 226
ILE A 225
GLY A 196
VAL A 160
LEU A 171
 None
 0.95A 3v8vA-2pigA:
undetectable		 3v8vA-2pigA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2pig PUTATIVE TRANSFERASE
(Salmonella
enterica) 		5 / 12 ILE A 138
ALA A 140
ILE A 109
LEU A 152
VAL A 113
 None
 0.87A 4k6iA-2pigA:
undetectable		 4k6iA-2pigA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 2pig PUTATIVE TRANSFERASE
(Salmonella
enterica) 		3 / 3 TYR A  87
ARG A 121
SER A 104
 None
 1.00A 4khpI-2pigA:
undetectable
4khpJ-2pigA:
undetectable		 4khpI-2pigA:
17.51
4khpJ-2pigA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2pig PUTATIVE TRANSFERASE
(Salmonella
enterica) 		3 / 3 ALA A 101
GLN A  16
GLY A  19
 None
 0.65A 4odoC-2pigA:
undetectable		 4odoC-2pigA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UW0_A_SAMA1506_0
(WBDD)		 2pig PUTATIVE TRANSFERASE
(Salmonella
enterica) 		5 / 12 TYR A 155
ALA A 158
ILE A 194
VAL A 188
ILE A 204
 None
 1.04A 4uw0A-2pigA:
undetectable		 4uw0A-2pigA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 2pig PUTATIVE TRANSFERASE
(Salmonella
enterica) 		4 / 8 TYR A 211
ILE A 289
SER A 290
GLY A 254
 None
 0.85A 5alcL-2pigA:
undetectable		 5alcL-2pigA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2pig PUTATIVE TRANSFERASE
(Salmonella
enterica) 		5 / 11 ILE A 103
ILE A 109
THR A  72
ILE A  74
ALA A  78
 None
 0.97A 5lg3A-2pigA:
undetectable		 5lg3A-2pigA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_B_FJQB501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 2pig PUTATIVE TRANSFERASE
(Salmonella
enterica) 		5 / 11 ALA A 101
VAL A  96
ILE A  74
ALA A 107
LEU A  86
 None
 1.12A 6h1lB-2pigA:
undetectable		 6h1lB-2pigA:
22.53