SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pjd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		3 / 4 LYS A  88
ALA A  91
MET A 124
 None
 0.75A 1hk3A-2pjdA:
undetectable		 1hk3A-2pjdA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		4 / 6 LEU A  11
ALA A   7
LEU A  12
THR A   5
 None
 1.08A 1ictB-2pjdA:
undetectable		 1ictB-2pjdA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		5 / 12 GLY A 204
GLY A 206
VAL A 228
ASN A 268
PRO A 270
 None
 0.77A 1nv8A-2pjdA:
17.3		 1nv8A-2pjdA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_1
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		3 / 3 GLY A 204
ASP A 227
ASN A 268
 None
 0.54A 1vq1A-2pjdA:
18.2		 1vq1A-2pjdA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		5 / 12 ASP A 202
GLY A 204
GLY A 206
LEU A 210
ASN A 268
 None
 0.51A 2nxeA-2pjdA:
18.5		 2nxeA-2pjdA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		5 / 12 ASP A 202
GLY A 204
GLY A 206
LEU A 210
ASN A 268
 None
 0.50A 2nxeB-2pjdA:
18.8		 2nxeB-2pjdA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		6 / 12 GLY A 204
GLY A 206
LEU A 210
VAL A 254
ASN A 268
PRO A 270
 None
 0.86A 2zulA-2pjdA:
32.8		 2zulA-2pjdA:
29.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		5 / 12 LEU A 188
LEU A 210
ALA A 303
VAL A 203
PHE A 255
 None
 1.22A 3b0wA-2pjdA:
undetectable		 3b0wA-2pjdA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		3 / 3 GLY A 206
ASP A 227
SER A 229
 None
 0.54A 3brfA-2pjdA:
undetectable		 3brfA-2pjdA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		5 / 12 GLY A 204
GLY A 206
VAL A 254
ASN A 268
PRO A 270
 None
 0.85A 3dmfA-2pjdA:
33.2		 3dmfA-2pjdA:
29.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		6 / 12 GLY A 204
GLY A 206
LEU A 210
VAL A 254
ASN A 268
PRO A 270
 None
 0.86A 3dmhA-2pjdA:
33.2		 3dmhA-2pjdA:
29.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		4 / 8 ALA A  91
GLN A  94
ASP A  28
TYR A  82
 None
 1.00A 3qj7A-2pjdA:
undetectable
3qj7D-2pjdA:
undetectable		 3qj7A-2pjdA:
24.73
3qj7D-2pjdA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		3 / 3 LYS A 330
VAL A 322
HIS A 320
 None
 1.12A 3tj7A-2pjdA:
undetectable		 3tj7A-2pjdA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		5 / 11 GLY A 206
ASP A 227
VAL A 254
ASN A 268
PRO A 270
 None
 0.90A 3v8vB-2pjdA:
12.7		 3v8vB-2pjdA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		5 / 12 PRO A 269
LEU A 285
LEU A 313
ILE A 301
TYR A 332
 None
 1.19A 4a79A-2pjdA:
undetectable		 4a79A-2pjdA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		5 / 12 PRO A 269
LEU A 285
LEU A 313
ILE A 301
TYR A 332
 None
 1.19A 4a79B-2pjdA:
undetectable		 4a79B-2pjdA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DCM_A_SAMA401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE G)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		7 / 11 ASP A 202
GLY A 204
GLY A 206
ASP A 227
ASN A 253
ASN A 268
PRO A 270
 None
 0.71A 4dcmA-2pjdA:
31.3		 4dcmA-2pjdA:
27.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_B_15UB402_1
(PROTHROMBIN)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		5 / 12 TRP A 159
ALA A 238
ASP A 202
GLY A 206
GLY A 204
 None
 0.99A 4hfpB-2pjdA:
undetectable		 4hfpB-2pjdA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		4 / 7 THR A 239
ALA A 235
THR A 171
VAL A 169
 None
 0.83A 4ik7A-2pjdA:
undetectable		 4ik7A-2pjdA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		4 / 8 THR A 239
ALA A 235
THR A 171
VAL A 169
 None
 0.82A 4ik7B-2pjdA:
undetectable		 4ik7B-2pjdA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_A_CL6A502_1
(CYTOCHROME P-450)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		4 / 5 LEU A 188
ALA A 213
VAL A 200
ILE A 221
 None
 0.89A 4xe3A-2pjdA:
undetectable		 4xe3A-2pjdA:
26.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		4 / 5 LEU A 188
ALA A 213
VAL A 200
ILE A 221
 None
 0.86A 4xe3B-2pjdA:
undetectable		 4xe3B-2pjdA:
26.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		3 / 3 GLY A 206
ASP A 227
ASN A 253
 None
 0.43A 5jglA-2pjdA:
16.2		 5jglA-2pjdA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C
(Escherichia
coli) 		4 / 7 LEU A  11
THR A 106
ASP A  78
LEU A  33
 None
 1.08A 5jq7B-2pjdA:
undetectable		 5jq7B-2pjdA:
17.87