SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pjq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		3 / 3 ASP A  28
ARG A  32
ILE A 131
 None
 0.88A 1a4gB-2pjqA:
undetectable		 1a4gB-2pjqA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		5 / 10 ALA A  37
LEU A  52
LEU A  50
ILE A  97
HIS A  58
 None
 0.99A 1a52A-2pjqA:
undetectable		 1a52A-2pjqA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		5 / 10 ALA A  37
LEU A  52
LEU A  50
ILE A  97
HIS A  58
 None
 0.97A 1a52B-2pjqA:
undetectable		 1a52B-2pjqA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		5 / 9 ALA A  37
LEU A  52
LEU A  50
ILE A  97
HIS A  58
 None
 0.94A 1ereA-2pjqA:
undetectable		 1ereA-2pjqA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		5 / 9 ALA A  37
LEU A  52
LEU A  50
ILE A  97
HIS A  58
 None
 0.93A 1ereB-2pjqA:
undetectable		 1ereB-2pjqA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		5 / 9 ALA A  37
LEU A  52
LEU A  50
ILE A  97
HIS A  58
 None
 0.93A 1ereC-2pjqA:
undetectable		 1ereC-2pjqA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		5 / 9 ALA A  37
LEU A  52
LEU A  50
ILE A  97
HIS A  58
 None
 0.94A 1ereD-2pjqA:
undetectable		 1ereD-2pjqA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		4 / 8 ALA A  37
LEU A  52
LEU A  50
HIS A  58
 None
 0.97A 1ereE-2pjqA:
undetectable		 1ereE-2pjqA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		4 / 8 ALA A  37
LEU A  52
LEU A  50
HIS A  58
 None
 0.97A 1ereF-2pjqA:
undetectable		 1ereF-2pjqA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		5 / 10 ALA A  37
LEU A  52
LEU A  50
ILE A  97
HIS A  58
 None
 0.96A 1pcgA-2pjqA:
undetectable		 1pcgA-2pjqA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		5 / 10 ALA A  37
LEU A  52
LEU A  50
ILE A  97
HIS A  58
 None
 0.96A 1qkuA-2pjqA:
undetectable		 1qkuA-2pjqA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		5 / 10 ALA A  37
LEU A  52
LEU A  50
ILE A  97
HIS A  58
 None
 0.97A 1qkuB-2pjqA:
undetectable		 1qkuB-2pjqA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		5 / 10 ALA A  37
LEU A  52
LEU A  50
ILE A  97
HIS A  58
 None
 0.97A 1qkuC-2pjqA:
undetectable		 1qkuC-2pjqA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		3 / 3 ASP A  43
ARG A  39
ASP A 188
 None
 0.94A 1vptA-2pjqA:
undetectable		 1vptA-2pjqA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		4 / 6 TYR A 163
GLY A  24
SER A  23
ARG A 135
 None
 1.29A 2a3cA-2pjqA:
undetectable		 2a3cA-2pjqA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		4 / 6 TYR A 163
GLY A  24
SER A  23
ARG A 135
 None
 1.31A 2a3cB-2pjqA:
undetectable		 2a3cB-2pjqA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		5 / 12 ALA A 190
LEU A 193
ALA A 194
THR A 198
ILE A 131
 None
 0.74A 2jjpA-2pjqA:
undetectable		 2jjpA-2pjqA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		5 / 11 HIS A  29
VAL A  33
LEU A 181
ILE A  97
VAL A 119
 None
 1.14A 2uxoB-2pjqA:
undetectable		 2uxoB-2pjqA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		5 / 12 ALA A  37
LEU A  52
LEU A  50
ILE A  97
HIS A  58
 None
 0.95A 2yjaB-2pjqA:
undetectable		 2yjaB-2pjqA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		5 / 12 ALA A  37
LEU A  52
LEU A  50
ILE A  97
HIS A  58
 None
 0.98A 3q95A-2pjqA:
undetectable		 3q95A-2pjqA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		3 / 3 ARG A  32
ARG A  35
ILE A 131
 None
 0.84A 4b7qA-2pjqA:
undetectable		 4b7qA-2pjqA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		3 / 3 ARG A  32
ARG A  35
ILE A 131
 None
 0.89A 4b7qC-2pjqA:
undetectable		 4b7qC-2pjqA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		4 / 8 ILE A  10
LEU A  80
ILE A  96
PHE A  94
 None
 0.82A 4hb6A-2pjqA:
undetectable		 4hb6A-2pjqA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		4 / 8 ILE A  10
LEU A  80
ILE A  96
PHE A  94
 None
 0.69A 4hb8A-2pjqA:
undetectable		 4hb8A-2pjqA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		5 / 11 ALA A  37
LEU A  52
LEU A  50
ILE A  97
HIS A  58
 None
 0.92A 5dxbB-2pjqA:
undetectable		 5dxbB-2pjqA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2pjq UNCHARACTERIZED
PROTEIN LP_2664
(Lactobacillus
plantarum) 		5 / 9 ILE A  93
LEU A  57
ILE A   2
ASN A  49
ALA A  37
 None
 0.92A 5nunA-2pjqA:
undetectable		 5nunA-2pjqA:
19.20