SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pjs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOS_A_VIAA1_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 2pjs UNCHARACTERIZED
PROTEIN ATU1953
(Agrobacterium
fabrum) 		5 / 12 LEU A 102
SER A  42
MET A  28
PHE A  21
ILE A 110
 None
 1.30A 1xosA-2pjsA:
undetectable		 1xosA-2pjsA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOT_A_VDNA101_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 2pjs UNCHARACTERIZED
PROTEIN ATU1953
(Agrobacterium
fabrum) 		5 / 12 LEU A 102
SER A  42
MET A  28
PHE A  21
ILE A 110
 None
 1.21A 1xotA-2pjsA:
undetectable		 1xotA-2pjsA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 2pjs UNCHARACTERIZED
PROTEIN ATU1953
(Agrobacterium
fabrum) 		4 / 6 PHE A 101
ARG A 103
GLY A  56
THR A  60
 None
 1.05A 2f7fA-2pjsA:
undetectable		 2f7fA-2pjsA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 2pjs UNCHARACTERIZED
PROTEIN ATU1953
(Agrobacterium
fabrum) 		4 / 8 GLU A  55
TYR A  88
PHE A 101
GLY A  59
 None
 0.81A 2ha4A-2pjsA:
undetectable		 2ha4A-2pjsA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 2pjs UNCHARACTERIZED
PROTEIN ATU1953
(Agrobacterium
fabrum) 		4 / 8 SER A  58
VAL A  97
PHE A 101
ASN A 111
 None
 1.24A 2wekA-2pjsA:
undetectable		 2wekA-2pjsA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 2pjs UNCHARACTERIZED
PROTEIN ATU1953
(Agrobacterium
fabrum) 		4 / 8 SER A  58
VAL A  97
PHE A 101
ASN A 111
 None
 1.24A 2wekB-2pjsA:
undetectable		 2wekB-2pjsA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 2pjs UNCHARACTERIZED
PROTEIN ATU1953
(Agrobacterium
fabrum) 		5 / 11 GLY A  83
ALA A  82
ILE A  25
ILE A 112
LEU A 100
 None
 1.08A 4dt8A-2pjsA:
undetectable		 4dt8A-2pjsA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 2pjs UNCHARACTERIZED
PROTEIN ATU1953
(Agrobacterium
fabrum) 		5 / 10 GLY A  83
ALA A  82
ILE A  25
ILE A 112
LEU A 100
 None
 1.08A 4dt8B-2pjsA:
undetectable		 4dt8B-2pjsA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_3
(HIV-1 PROTEASE)		 2pjs UNCHARACTERIZED
PROTEIN ATU1953
(Agrobacterium
fabrum) 		3 / 3 ASP A 104
LEU A  26
VAL A  30
 None
 0.49A 4jecB-2pjsA:
undetectable		 4jecB-2pjsA:
19.66