SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pju'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_2
(PHOSPHOLIPASE A2
HOMOLOG 2)		 2pju PROPIONATE
CATABOLISM OPERON
REGULATORY PROTEIN
(Escherichia
coli) 		5 / 11 LEU A 161
VAL A 157
GLY A 108
ARG A 133
TYR A 135
 None
 1.36A 1y4lB-2pjuA:
undetectable		 1y4lB-2pjuA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 2pju PROPIONATE
CATABOLISM OPERON
REGULATORY PROTEIN
(Escherichia
coli) 		4 / 7 ILE A  39
ILE A  42
ILE A  65
PHE A 186
 None
 0.75A 5fukA-2pjuA:
undetectable
5fukB-2pjuA:
undetectable		 5fukA-2pjuA:
22.81
5fukB-2pjuA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 2pju PROPIONATE
CATABOLISM OPERON
REGULATORY PROTEIN
(Escherichia
coli) 		5 / 11 SER A 106
GLY A 108
ALA A 166
VAL A 156
ASP A 131
 None
 1.01A 5i3cC-2pjuA:
undetectable		 5i3cC-2pjuA:
21.91