SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pjw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2pjw UNCHARACTERIZED
PROTEIN YHL002W
(Saccharomyces
cerevisiae) 		3 / 3 GLU H 289
ALA H 290
PHE H 293
 None
 0.60A 4v1fA-2pjwH:
3.5		 4v1fA-2pjwH:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2pjw UNCHARACTERIZED
PROTEIN YHL002W
(Saccharomyces
cerevisiae) 		3 / 3 GLU H 289
ALA H 290
PHE H 293
 None
 0.65A 4v1fC-2pjwH:
3.4		 4v1fC-2pjwH:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 2pjw UNCHARACTERIZED
PROTEIN YHL002W
VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 27
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		3 / 3 ASN H 307
SER H 310
ARG V 426
 None
 0.92A 5b2qA-2pjwH:
2.4		 5b2qA-2pjwH:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 2pjw UNCHARACTERIZED
PROTEIN YHL002W
VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 27
(Saccharomyces
cerevisiae) 		5 / 12 GLU V 366
LEU H 359
ALA H 362
SER H 365
LEU V 364
 None
 1.19A 5nd4B-2pjwV:
undetectable		 5nd4B-2pjwV:
12.06