SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2plg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 2plg TLL0839 PROTEIN
(Synechococcus
elongatus) 		4 / 6 TRP A  52
VAL A  43
ILE A  51
LEU A 123
 None
 1.24A 1j96A-2plgA:
undetectable		 1j96A-2plgA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_1
(RETINOIC ACID
RECEPTOR, BETA)		 2plg TLL0839 PROTEIN
(Synechococcus
elongatus) 		5 / 12 ALA A 119
LEU A 134
ILE A 131
ILE A 135
LEU A  65
 None
 1.03A 1xdkB-2plgA:
undetectable		 1xdkB-2plgA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NAI_C_URFC521_1
(RNA DEPENDENT RNA
POLYMERASE)		 2plg TLL0839 PROTEIN
(Synechococcus
elongatus) 		4 / 5 ASP A 147
ASP A 146
ASP A 143
ARG A  55
 None
 1.27A 3naiC-2plgA:
undetectable		 3naiC-2plgA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_B_REAB503_1
(RETINOIC ACID
RECEPTOR BETA)		 2plg TLL0839 PROTEIN
(Synechococcus
elongatus) 		5 / 12 ALA A 119
LEU A 134
ILE A 131
ILE A 135
LEU A  65
 None
 1.07A 5uanB-2plgA:
undetectable		 5uanB-2plgA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2plg TLL0839 PROTEIN
(Synechococcus
elongatus) 		4 / 9 ILE A 126
ILE A  28
ILE A  32
LEU A  35
 None
 0.65A 5vkqB-2plgA:
undetectable
5vkqC-2plgA:
undetectable		 5vkqB-2plgA:
6.70
5vkqC-2plgA:
6.70