SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pma'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 2pma UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		4 / 7 LEU A  55
THR A  77
THR A  79
LEU A 118
 None
ACT  A 203 ( 3.8A)
ACT  A 203 (-2.9A)
None
 1.09A 5jq7B-2pmaA:
undetectable		 5jq7B-2pmaA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 2pma UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		4 / 5 VAL A  75
THR A  77
LEU A 118
LEU A 145
 None
ACT  A 203 ( 3.8A)
None
None
 0.75A 6bqgA-2pmaA:
undetectable		 6bqgA-2pmaA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 2pma UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		5 / 10 VAL A  75
ALA A  57
LEU A  35
LEU A 118
LEU A  42
 None
 0.98A 6f5uA-2pmaA:
undetectable
6f5uB-2pmaA:
undetectable		 6f5uA-2pmaA:
21.97
6f5uB-2pmaA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 2pma UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		5 / 10 VAL A  75
ALA A  57
LEU A  35
LEU A 118
LEU A  42
 None
 1.01A 6f6nA-2pmaA:
undetectable
6f6nB-2pmaA:
undetectable		 6f6nA-2pmaA:
21.97
6f6nB-2pmaA:
21.92