SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pmt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 2pmt GLUTATHIONE
TRANSFERASE
(Proteus
mirabilis) 		5 / 12 LEU A  18
LEU A  23
LEU A  76
ASN A  59
LEU A  57
 None
 1.08A 2bdmA-2pmtA:
3.2		 2bdmA-2pmtA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_2
(ADENOSYLHOMOCYSTEINA
SE)		 2pmt GLUTATHIONE
TRANSFERASE
(Proteus
mirabilis) 		4 / 5 GLN A 163
THR A 160
GLU A 198
THR A 197
 None
 1.30A 3glqA-2pmtA:
undetectable		 3glqA-2pmtA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_2
(ADENOSYLHOMOCYSTEINA
SE)		 2pmt GLUTATHIONE
TRANSFERASE
(Proteus
mirabilis) 		4 / 5 GLN A 163
THR A 160
GLU A 198
THR A 197
 None
 1.31A 3glqB-2pmtA:
undetectable		 3glqB-2pmtA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2pmt GLUTATHIONE
TRANSFERASE
(Proteus
mirabilis) 		4 / 5 GLN A 163
THR A 160
GLU A 198
THR A 197
 None
 1.37A 3n58A-2pmtA:
undetectable		 3n58A-2pmtA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 2pmt GLUTATHIONE
TRANSFERASE
(Proteus
mirabilis) 		5 / 12 ILE A  27
THR A  21
ARG A  19
VAL A 153
LEU A  55
 None
 1.28A 4qzuA-2pmtA:
undetectable		 4qzuA-2pmtA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 2pmt GLUTATHIONE
TRANSFERASE
(Proteus
mirabilis) 		4 / 7 ILE A  69
LEU A  55
MET A   1
LEU A  57
 None
 0.90A 5u4sA-2pmtA:
undetectable		 5u4sA-2pmtA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2pmt GLUTATHIONE
TRANSFERASE
(Proteus
mirabilis) 		5 / 7 ILE A  46
GLN A  56
VAL A  54
ILE A  30
THR A   6
 None
 1.41A 6cduF-2pmtA:
3.9
6cduG-2pmtA:
2.1		 6cduF-2pmtA:
21.23
6cduG-2pmtA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 2pmt GLUTATHIONE
TRANSFERASE
(Proteus
mirabilis) 		5 / 12 ILE A  16
PHE A  25
THR A 197
THR A 160
LEU A 161
 None
 1.37A 6djzB-2pmtA:
undetectable		 6djzB-2pmtA:
20.92