SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pn1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DTL_A_BEPA205_1 (CARDIAC TROPONIN C)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	5 / 12	LEU A 264 PHE A 253 LEU A 251 LEU A 247 MET A 117	None	1.18A	1dtlA-2pn1A: undetectable	1dtlA-2pn1A: 17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IBG_H_OBNH1_1 (IGG2B-KAPPA 40-50 FAB (HEAVY CHAIN))	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 6	LEU A 6 PHE A 21 TYR A 199 VAL A 18	None	1.15A	1ibgH-2pn1A: undetectable	1ibgH-2pn1A: 19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MZ9_A_VDYA1002_3 (CARTILAGE OLIGOMERIC MATRIX PROTEIN)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 5	ILE A 8 LEU A 76 ALA A 107 CYH A 108	None	0.87A	1mz9C-2pn1A: undetectable	1mz9C-2pn1A: 10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T86_A_CAMA1422_0 (CYTOCHROME P450-CAM)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 8	THR A 9 THR A 90 VAL A 102 VAL A 98	None	0.91A	1t86A-2pn1A: undetectable	1t86A-2pn1A: 21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V54_C_CHDC3271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE III CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 8	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.83A	1v54C-2pn1A: undetectable 1v54J-2pn1A: undetectable	1v54C-2pn1A: 20.12 1v54J-2pn1A: 9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V54_P_CHDP4271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE III CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 8	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.83A	1v54P-2pn1A: undetectable 1v54W-2pn1A: undetectable	1v54P-2pn1A: 20.12 1v54W-2pn1A: 9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYR_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 8	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.84A	2dyrC-2pn1A: undetectable 2dyrJ-2pn1A: undetectable	2dyrC-2pn1A: 20.12 2dyrJ-2pn1A: 9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYR_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 8	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.82A	2dyrP-2pn1A: undetectable 2dyrW-2pn1A: undetectable	2dyrP-2pn1A: 20.12 2dyrW-2pn1A: 9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIK_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 7	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.82A	2eikC-2pn1A: undetectable 2eikJ-2pn1A: undetectable	2eikC-2pn1A: 20.12 2eikJ-2pn1A: 9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIK_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 8	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.81A	2eikP-2pn1A: undetectable 2eikW-2pn1A: undetectable	2eikP-2pn1A: 20.12 2eikW-2pn1A: 9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIL_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 8	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.83A	2eilC-2pn1A: undetectable 2eilJ-2pn1A: undetectable	2eilC-2pn1A: 20.12 2eilJ-2pn1A: 9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIL_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 8	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.82A	2eilP-2pn1A: undetectable 2eilW-2pn1A: undetectable	2eilP-2pn1A: 20.12 2eilW-2pn1A: 9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG2_C_CHDC271_0 (CYTOCHROME C OXIDASE SUBUNIT 3)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 7	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.81A	3ag2C-2pn1A: undetectable	3ag2C-2pn1A: 20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG2_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 7	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.84A	3ag2P-2pn1A: undetectable 3ag2W-2pn1A: undetectable	3ag2P-2pn1A: 20.12 3ag2W-2pn1A: 9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG4_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 7	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.83A	3ag4P-2pn1A: undetectable 3ag4W-2pn1A: undetectable	3ag4P-2pn1A: 20.12 3ag4W-2pn1A: 9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASN_C_CHDC271_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 7	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.82A	3asnC-2pn1A: undetectable 3asnJ-2pn1A: undetectable	3asnC-2pn1A: 20.12 3asnJ-2pn1A: 9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASO_C_CHDC271_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 8	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.82A	3asoC-2pn1A: undetectable 3asoJ-2pn1A: undetectable	3asoC-2pn1A: 20.12 3asoJ-2pn1A: 9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BRF_A_SORA1_0 (LIN-12 AND GLP-1 PHENOTYPE PROTEIN 1, ISOFORM A)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	3 / 3	GLY A 12 ASP A 34 SER A 36	None	0.63A	3brfA-2pn1A: undetectable	3brfA-2pn1A: 22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IJD_A_C2FA314_0 (UNCHARACTERIZED PROTEIN)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	5 / 12	THR A 9 LEU A 63 VAL A 98 GLY A 97 LEU A 86	None	1.01A	3ijdA-2pn1A: undetectable	3ijdA-2pn1A: 21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_S_TFPS202_2 (PROTEIN S100-A4)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	3 / 3	GLU A 239 LEU A 242 ASP A 243	None	0.43A	3ko0T-2pn1A: undetectable	3ko0T-2pn1A: 16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_C_CELC682_2 (PROSTAGLANDIN G/H SYNTHASE 2)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 7	SER A 36 LEU A 7 ARG A 330 ILE A 328	None	1.04A	3ln1C-2pn1A: undetectable	3ln1C-2pn1A: 21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3X2Q_C_CHDC304_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 7	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.83A	3x2qC-2pn1A: undetectable 3x2qJ-2pn1A: undetectable	3x2qC-2pn1A: 20.12 3x2qJ-2pn1A: 9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3X2Q_P_CHDP307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 7	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.81A	3x2qP-2pn1A: undetectable 3x2qW-2pn1A: undetectable	3x2qP-2pn1A: 20.12 3x2qW-2pn1A: 9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L4A_A_CAMA502_0 (CAMPHOR 5-MONOOXYGENASE)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 8	THR A 9 THR A 90 VAL A 102 VAL A 98	None	0.94A	4l4aA-2pn1A: undetectable	4l4aA-2pn1A: 21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QZU_A_RTLA201_0 (RETINOL-BINDING PROTEIN 2)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	5 / 12	PHE A 25 ILE A 8 VAL A 248 LEU A 76 LEU A 293	None	1.36A	4qzuA-2pn1A: undetectable	4qzuA-2pn1A: 16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1A_C_CHDC304_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 7	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.88A	5b1aC-2pn1A: undetectable 5b1aJ-2pn1A: undetectable	5b1aC-2pn1A: 20.12 5b1aJ-2pn1A: 9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1A_P_CHDP305_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 7	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.85A	5b1aP-2pn1A: undetectable 5b1aW-2pn1A: undetectable	5b1aP-2pn1A: 20.12 5b1aW-2pn1A: 9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1B_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 7	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.87A	5b1bP-2pn1A: undetectable 5b1bW-2pn1A: undetectable	5b1bP-2pn1A: 20.12 5b1bW-2pn1A: 9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B3S_C_CHDC307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 7	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.83A	5b3sC-2pn1A: undetectable 5b3sJ-2pn1A: undetectable	5b3sC-2pn1A: 20.12 5b3sJ-2pn1A: 9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B3S_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 3)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 7	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.84A	5b3sP-2pn1A: undetectable	5b3sP-2pn1A: 20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IY5_C_CHDC307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 7	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.76A	5iy5C-2pn1A: undetectable 5iy5J-2pn1A: undetectable	5iy5C-2pn1A: 20.71 5iy5J-2pn1A: 10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z84_C_CHDC307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 7	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.84A	5z84C-2pn1A: undetectable 5z84J-2pn1A: undetectable	5z84C-2pn1A: 20.12 5z84J-2pn1A: 9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z85_C_CHDC306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	4 / 7	LEU A 289 GLN A 288 PHE A 21 LEU A 76	None	0.87A	5z85C-2pn1A: undetectable 5z85J-2pn1A: undetectable	5z85C-2pn1A: 20.12 5z85J-2pn1A: 9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B0C_D_TA1D502_1 (TUBULIN BETA CHAIN)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	5 / 12	VAL A 72 LEU A 76 ALA A 74 LEU A 289 GLY A 28	None	1.00A	6b0cD-2pn1A: undetectable	6b0cD-2pn1A: 16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CZM_E_HISE402_0 (ATP PHOSPHORIBOSYLTRANSF ERASE CATALYTIC SUBUNIT)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	5 / 9	VAL A 248 VAL A 100 GLY A 84 LEU A 83 CYH A 108	None	1.31A	6czmD-2pn1A: undetectable 6czmE-2pn1A: undetectable	6czmD-2pn1A: 21.47 6czmE-2pn1A: 21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CZM_F_HISF402_0 (ATP PHOSPHORIBOSYLTRANSF ERASE CATALYTIC SUBUNIT)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	5 / 10	VAL A 248 VAL A 100 GLY A 84 LEU A 83 CYH A 108	None	1.30A	6czmE-2pn1A: undetectable 6czmF-2pn1A: undetectable	6czmE-2pn1A: 21.47 6czmF-2pn1A: 21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6G2P_B_TRPB502_0 (FLAVIN-DEPENDENT L-TRYPTOPHAN OXIDASE VIOA)	2pn1	CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT (Exiguobacterium sibiricum)	5 / 10	ARG A 227 LEU A 262 LEU A 194 ASP A 257 VAL A 234	None	1.33A	6g2pB-2pn1A: undetectable	6g2pB-2pn1A: 23.64

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DTL_A_BEPA205_1","CARDIAC TROPONIN C","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",5,"LEU A 264;PHE A 253;LEU A 251;LEU A 247;MET A 117","None","1.18A","1dtlA-2pn1A:undetectable","1dtlA-2pn1A:17.96"],["1IBG_H_OBNH1_1","IGG2B-KAPPA 40-50 FAB (HEAVY CHAIN)","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A   6;PHE A  21;TYR A 199;VAL A  18","None","1.15A","1ibgH-2pn1A:undetectable","1ibgH-2pn1A:19.34"],["1MZ9_A_VDYA1002_3","CARTILAGE OLIGOMERIC MATRIX PROTEIN;CARTILAGE OLIGOMERIC MATRIX PROTEIN","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"ILE A   8;LEU A  76;ALA A 107;CYH A 108","None","0.87A","1mz9C-2pn1A:undetectable","1mz9C-2pn1A:10.99"],["1T86_A_CAMA1422_0","CYTOCHROME P450-CAM","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"THR A   9;THR A  90;VAL A 102;VAL A  98","None","0.91A","1t86A-2pn1A:undetectable","1t86A-2pn1A:21.68"],["1V54_C_CHDC3271_0","CYTOCHROME C OXIDASE POLYPEPTIDE III;CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.83A","1v54C-2pn1A:undetectable;1v54J-2pn1A:undetectable","1v54C-2pn1A:20.12;1v54J-2pn1A:9.61"],["1V54_P_CHDP4271_0","CYTOCHROME C OXIDASE POLYPEPTIDE III;CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.83A","1v54P-2pn1A:undetectable;1v54W-2pn1A:undetectable","1v54P-2pn1A:20.12;1v54W-2pn1A:9.61"],["2DYR_C_CHDC271_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 3","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.84A","2dyrC-2pn1A:undetectable;2dyrJ-2pn1A:undetectable","2dyrC-2pn1A:20.12;2dyrJ-2pn1A:9.61"],["2DYR_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 3","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.82A","2dyrP-2pn1A:undetectable;2dyrW-2pn1A:undetectable","2dyrP-2pn1A:20.12;2dyrW-2pn1A:9.61"],["2EIK_C_CHDC271_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 3","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.82A","2eikC-2pn1A:undetectable;2eikJ-2pn1A:undetectable","2eikC-2pn1A:20.12;2eikJ-2pn1A:9.61"],["2EIK_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 3","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.81A","2eikP-2pn1A:undetectable;2eikW-2pn1A:undetectable","2eikP-2pn1A:20.12;2eikW-2pn1A:9.61"],["2EIL_C_CHDC271_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 3","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.83A","2eilC-2pn1A:undetectable;2eilJ-2pn1A:undetectable","2eilC-2pn1A:20.12;2eilJ-2pn1A:9.61"],["2EIL_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 3","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.82A","2eilP-2pn1A:undetectable;2eilW-2pn1A:undetectable","2eilP-2pn1A:20.12;2eilW-2pn1A:9.61"],["3AG2_C_CHDC271_0","CYTOCHROME C OXIDASE SUBUNIT 3","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.81A","3ag2C-2pn1A:undetectable","3ag2C-2pn1A:20.12"],["3AG2_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.84A","3ag2P-2pn1A:undetectable;3ag2W-2pn1A:undetectable","3ag2P-2pn1A:20.12;3ag2W-2pn1A:9.61"],["3AG4_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.83A","3ag4P-2pn1A:undetectable;3ag4W-2pn1A:undetectable","3ag4P-2pn1A:20.12;3ag4W-2pn1A:9.61"],["3ASN_C_CHDC271_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.82A","3asnC-2pn1A:undetectable;3asnJ-2pn1A:undetectable","3asnC-2pn1A:20.12;3asnJ-2pn1A:9.61"],["3ASO_C_CHDC271_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.82A","3asoC-2pn1A:undetectable;3asoJ-2pn1A:undetectable","3asoC-2pn1A:20.12;3asoJ-2pn1A:9.61"],["3BRF_A_SORA1_0","LIN-12 AND GLP-1 PHENOTYPE PROTEIN 1, ISOFORM A","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",3,"GLY A  12;ASP A  34;SER A  36","None","0.63A","3brfA-2pn1A:undetectable","3brfA-2pn1A:22.13"],["3IJD_A_C2FA314_0","UNCHARACTERIZED PROTEIN","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",5,"THR A   9;LEU A  63;VAL A  98;GLY A  97;LEU A  86","None","1.01A","3ijdA-2pn1A:undetectable","3ijdA-2pn1A:21.67"],["3KO0_S_TFPS202_2","PROTEIN S100-A4;PROTEIN S100-A4","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",3,"GLU A 239;LEU A 242;ASP A 243","None","0.43A","3ko0T-2pn1A:undetectable","3ko0T-2pn1A:16.77"],["3LN1_C_CELC682_2","PROSTAGLANDIN G\/H SYNTHASE 2","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"SER A  36;LEU A   7;ARG A 330;ILE A 328","None","1.04A","3ln1C-2pn1A:undetectable","3ln1C-2pn1A:21.12"],["3X2Q_C_CHDC304_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.83A","3x2qC-2pn1A:undetectable;3x2qJ-2pn1A:undetectable","3x2qC-2pn1A:20.12;3x2qJ-2pn1A:9.61"],["3X2Q_P_CHDP307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.81A","3x2qP-2pn1A:undetectable;3x2qW-2pn1A:undetectable","3x2qP-2pn1A:20.12;3x2qW-2pn1A:9.61"],["4L4A_A_CAMA502_0","CAMPHOR 5-MONOOXYGENASE","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"THR A   9;THR A  90;VAL A 102;VAL A  98","None","0.94A","4l4aA-2pn1A:undetectable","4l4aA-2pn1A:21.50"],["4QZU_A_RTLA201_0","RETINOL-BINDING PROTEIN 2","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",5,"PHE A  25;ILE A   8;VAL A 248;LEU A  76;LEU A 293","None","1.36A","4qzuA-2pn1A:undetectable","4qzuA-2pn1A:16.12"],["5B1A_C_CHDC304_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.88A","5b1aC-2pn1A:undetectable;5b1aJ-2pn1A:undetectable","5b1aC-2pn1A:20.12;5b1aJ-2pn1A:9.61"],["5B1A_P_CHDP305_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.85A","5b1aP-2pn1A:undetectable;5b1aW-2pn1A:undetectable","5b1aP-2pn1A:20.12;5b1aW-2pn1A:9.61"],["5B1B_P_CHDP306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.87A","5b1bP-2pn1A:undetectable;5b1bW-2pn1A:undetectable","5b1bP-2pn1A:20.12;5b1bW-2pn1A:9.61"],["5B3S_C_CHDC307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.83A","5b3sC-2pn1A:undetectable;5b3sJ-2pn1A:undetectable","5b3sC-2pn1A:20.12;5b3sJ-2pn1A:9.61"],["5B3S_P_CHDP306_0","CYTOCHROME C OXIDASE SUBUNIT 3","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.84A","5b3sP-2pn1A:undetectable","5b3sP-2pn1A:20.12"],["5IY5_C_CHDC307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.76A","5iy5C-2pn1A:undetectable;5iy5J-2pn1A:undetectable","5iy5C-2pn1A:20.71;5iy5J-2pn1A:10.64"],["5Z84_C_CHDC307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.84A","5z84C-2pn1A:undetectable;5z84J-2pn1A:undetectable","5z84C-2pn1A:20.12;5z84J-2pn1A:9.61"],["5Z85_C_CHDC306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",4,"LEU A 289;GLN A 288;PHE A  21;LEU A  76","None","0.87A","5z85C-2pn1A:undetectable;5z85J-2pn1A:undetectable","5z85C-2pn1A:20.12;5z85J-2pn1A:9.61"],["6B0C_D_TA1D502_1","TUBULIN BETA CHAIN","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",5,"VAL A  72;LEU A  76;ALA A  74;LEU A 289;GLY A  28","None","1.00A","6b0cD-2pn1A:undetectable","6b0cD-2pn1A:16.73"],["6CZM_E_HISE402_0","ATP PHOSPHORIBOSYLTRANSFERASE CATALYTIC SUBUNIT","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",5,"VAL A 248;VAL A 100;GLY A  84;LEU A  83;CYH A 108","None","1.31A","6czmD-2pn1A:undetectable;6czmE-2pn1A:undetectable","6czmD-2pn1A:21.47;6czmE-2pn1A:21.47"],["6CZM_F_HISF402_0","ATP PHOSPHORIBOSYLTRANSFERASE CATALYTIC SUBUNIT","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",5,"VAL A 248;VAL A 100;GLY A  84;LEU A  83;CYH A 108","None","1.30A","6czmE-2pn1A:undetectable;6czmF-2pn1A:undetectable","6czmE-2pn1A:21.47;6czmF-2pn1A:21.47"],["6G2P_B_TRPB502_0","FLAVIN-DEPENDENT L-TRYPTOPHAN OXIDASE VIOA","2pn1","CARBAMOYLPHOSPHATE SYNTHASE LARGE SUBUNIT","Exiguobacterium sibiricum",5,"ARG A 227;LEU A 262;LEU A 194;ASP A 257;VAL A 234","None","1.33A","6g2pB-2pn1A:undetectable","6g2pB-2pn1A:23.64"]]