SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pnc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 ALA A 427
VAL A 464
TRP A 474
 None
 0.95A 1av2A-2pncA:
undetectable
1av2B-2pncA:
undetectable		 1av2A-2pncA:
3.08
1av2B-2pncA:
3.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 6 PHE A 414
ALA A 342
GLY A 391
TYR A 392
 None
 0.97A 1gfzA-2pncA:
undetectable		 1gfzA-2pncA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IVV_A_DAHA382_1
(AMINE OXIDASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		7 / 10 TYR A 371
THR A 466
ASP A 471
TYR A 472
HIS A 519
HIS A 521
HIS A 683
 None
TPQ  A 470 ( 4.0A)
TPQ  A 470 (-3.6A)
CLU  A 808 (-3.4A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
CU  A 804 (-3.2A)
 0.65A 1ivvA-2pncA:
35.8		 1ivvA-2pncA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IVV_B_DAHB382_1
(AMINE OXIDASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		7 / 10 TYR A 371
THR A 466
ASP A 471
TYR A 472
HIS A 519
HIS A 521
HIS A 683
 None
TPQ  A 470 ( 4.0A)
TPQ  A 470 (-3.6A)
CLU  A 808 (-3.4A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
CU  A 804 (-3.2A)
 0.68A 1ivvB-2pncA:
36.8		 1ivvB-2pncA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 ASN A 286
PHE A 498
VAL A 288
 None
 0.86A 1kijA-2pncA:
undetectable		 1kijA-2pncA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 6 PHE A 414
ALA A 342
GLY A 391
TYR A 392
 None
 0.99A 1l5qB-2pncA:
undetectable		 1l5qB-2pncA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 6 PHE A 414
ALA A 342
GLY A 391
TYR A 392
 None
 1.01A 1l7xA-2pncA:
undetectable		 1l7xA-2pncA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 6 PHE A 414
ALA A 342
GLY A 391
TYR A 392
 None
 0.98A 1l7xB-2pncA:
undetectable		 1l7xB-2pncA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MSK_A_ACTA1302_0
(COBALAMIN-DEPENDENT
METHIONINE SYNTHASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 4 GLN A 279
VAL A 285
ARG A 268
TYR A 270
 None
 1.44A 1mskA-2pncA:
0.0		 1mskA-2pncA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA443_1
(ALPHA AMYLASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 8 SER A 344
ASP A  61
GLU A  66
TRP A 412
 None
 1.14A 1mxgA-2pncA:
undetectable		 1mxgA-2pncA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RI4_A_SAMA299_0
(MRNA CAPPING ENZYME)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		5 / 12 GLY A 368
ALA A 523
SER A 643
PHE A 388
SER A 386
 None
 1.21A 1ri4A-2pncA:
undetectable		 1ri4A-2pncA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 519
HIS A 521
HIS A 683
 CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
CU  A 804 (-3.2A)
 0.22A 1rjoA-2pncA:
35.8		 1rjoA-2pncA:
25.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 519
HIS A 521
HIS A 683
 CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
CU  A 804 (-3.2A)
 0.20A 1rkyA-2pncA:
40.5		 1rkyA-2pncA:
28.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 6 PRO A 241
GLY A 243
GLY A 227
TYR A 229
 None
 0.69A 1usqB-2pncA:
undetectable		 1usqB-2pncA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 6 PRO A 241
GLY A 243
GLY A 227
TYR A 229
 None
 0.67A 1usqC-2pncA:
undetectable		 1usqC-2pncA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 6 PRO A 241
GLY A 243
GLY A 227
TYR A 229
 None
 0.68A 1usqD-2pncA:
undetectable		 1usqD-2pncA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 6 PRO A 241
GLY A 243
GLY A 227
TYR A 229
 None
 0.68A 1usqE-2pncA:
undetectable		 1usqE-2pncA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 7 PRO A 241
GLY A 243
GLY A 227
TYR A 229
 None
 0.68A 1usqF-2pncA:
undetectable		 1usqF-2pncA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.59A 1v54A-2pncA:
undetectable		 1v54A-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.60A 1v54N-2pncA:
undetectable		 1v54N-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.60A 1v55A-2pncA:
undetectable		 1v55A-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.61A 1v55N-2pncA:
undetectable		 1v55N-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 519
HIS A 521
HIS A 683
 CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
CU  A 804 (-3.2A)
 0.25A 1w2zA-2pncA:
40.0		 1w2zA-2pncA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 519
HIS A 521
HIS A 683
 CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
CU  A 804 (-3.2A)
 0.19A 1w2zB-2pncA:
39.3		 1w2zB-2pncA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 519
HIS A 521
HIS A 683
 CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
CU  A 804 (-3.2A)
 0.21A 1w2zC-2pncA:
40.0		 1w2zC-2pncA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 519
HIS A 521
HIS A 683
 CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
CU  A 804 (-3.2A)
 0.18A 1w2zD-2pncA:
39.8		 1w2zD-2pncA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		5 / 12 TYR A 371
THR A 381
SER A 522
ILE A 494
TYR A 472
 None
None
None
TPQ  A 470 ( 4.8A)
CLU  A 808 (-3.4A)
 1.48A 1xvaA-2pncA:
undetectable		 1xvaA-2pncA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_A_SAMA500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		5 / 11 THR A 656
GLU A 139
ALA A 342
PRO A 169
PHE A 128
 None
 1.26A 2admA-2pncA:
undetectable		 2admA-2pncA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_B_SAMB500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		5 / 11 THR A 656
GLU A 139
ALA A 342
PRO A 169
PHE A 128
 None
 1.26A 2admB-2pncA:
undetectable		 2admB-2pncA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.57A 2dyrA-2pncA:
undetectable		 2dyrA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.60A 2dyrN-2pncA:
undetectable		 2dyrN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.56A 2dysA-2pncA:
undetectable		 2dysA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.54A 2dysN-2pncA:
undetectable		 2dysN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.57A 2eijA-2pncA:
undetectable		 2eijA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.60A 2eijN-2pncA:
undetectable		 2eijN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.56A 2eikA-2pncA:
undetectable		 2eikA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.61A 2eikN-2pncA:
undetectable		 2eikN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.55A 2eilA-2pncA:
undetectable		 2eilA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.60A 2eilN-2pncA:
undetectable		 2eilN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.62A 2eimA-2pncA:
undetectable		 2eimA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.59A 2eimN-2pncA:
undetectable		 2eimN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.52A 2einA-2pncA:
undetectable		 2einA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.59A 2einN-2pncA:
undetectable		 2einN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_A_TPFA2472_1
(CYTOCHROME P450 121)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		5 / 11 THR A 155
VAL A 154
ALA A 125
SER A  97
PHE A 343
 None
 1.40A 2ij7A-2pncA:
0.0		 2ij7A-2pncA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_D_TPFD2473_1
(CYTOCHROME P450 121)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		5 / 10 THR A 155
VAL A 154
ALA A 125
SER A  97
PHE A 343
 None
 1.37A 2ij7D-2pncA:
0.0		 2ij7D-2pncA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 6 PRO A 241
GLY A 243
GLY A 227
TYR A 229
 None
 0.72A 2jkjA-2pncA:
undetectable		 2jkjA-2pncA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 6 PRO A 241
GLY A 243
GLY A 227
TYR A 229
 None
 0.73A 2jkjB-2pncA:
undetectable		 2jkjB-2pncA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 6 PRO A 241
GLY A 243
GLY A 227
TYR A 229
 None
 0.72A 2jkjC-2pncA:
undetectable		 2jkjC-2pncA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 7 PRO A 241
GLY A 243
GLY A 227
TYR A 229
 None
 0.72A 2jkjE-2pncA:
undetectable		 2jkjE-2pncA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 6 PRO A 241
GLY A 243
GLY A 227
TYR A 229
 None
 0.67A 2jklB-2pncA:
undetectable		 2jklB-2pncA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 7 PRO A 241
GLY A 243
GLY A 227
TYR A 229
 None
 0.67A 2jklE-2pncA:
undetectable		 2jklE-2pncA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 519
HIS A 521
HIS A 683
 CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
CU  A 804 (-3.2A)
 0.18A 2oqeA-2pncA:
36.9		 2oqeA-2pncA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 519
HIS A 521
HIS A 683
 CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
CU  A 804 (-3.2A)
 0.18A 2oqeB-2pncA:
36.8		 2oqeB-2pncA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 519
HIS A 521
HIS A 683
 CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
CU  A 804 (-3.2A)
 0.18A 2oqeC-2pncA:
37.0		 2oqeC-2pncA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 519
HIS A 521
HIS A 683
 CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
CU  A 804 (-3.2A)
 0.18A 2oqeD-2pncA:
36.9		 2oqeD-2pncA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 519
HIS A 521
HIS A 683
 CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
CU  A 804 (-3.2A)
 0.19A 2oqeF-2pncA:
37.1		 2oqeF-2pncA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 519
HIS A 521
HIS A 683
 CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
CU  A 804 (-3.2A)
 0.26A 2w0qA-2pncA:
37.6		 2w0qA-2pncA:
25.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 519
HIS A 521
HIS A 683
 CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
CU  A 804 (-3.2A)
 0.24A 2w0qB-2pncA:
37.6		 2w0qB-2pncA:
25.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.64A 2y69A-2pncA:
undetectable		 2y69A-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.69A 2y69N-2pncA:
undetectable		 2y69N-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 TYR A 229
GLU A 245
THR A 381
 None
 1.04A 2y7hB-2pncA:
undetectable		 2y7hB-2pncA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.65A 2zxwA-2pncA:
undetectable		 2zxwA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.64A 2zxwN-2pncA:
undetectable		 2zxwN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.63A 3abkA-2pncA:
undetectable		 3abkA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.64A 3abkN-2pncA:
undetectable		 3abkN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.60A 3ablA-2pncA:
undetectable		 3ablA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.61A 3ablN-2pncA:
undetectable		 3ablN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.64A 3abmA-2pncA:
undetectable		 3abmA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.64A 3abmN-2pncA:
undetectable		 3abmN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.65A 3ag1A-2pncA:
undetectable		 3ag1A-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.67A 3ag1N-2pncA:
undetectable		 3ag1N-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.63A 3ag2A-2pncA:
undetectable		 3ag2A-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.63A 3ag2N-2pncA:
undetectable		 3ag2N-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.64A 3ag3A-2pncA:
undetectable		 3ag3A-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.64A 3ag3N-2pncA:
undetectable		 3ag3N-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.69A 3ag4A-2pncA:
undetectable		 3ag4A-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.69A 3ag4N-2pncA:
undetectable		 3ag4N-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.63A 3asnA-2pncA:
undetectable		 3asnA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.65A 3asnN-2pncA:
undetectable		 3asnN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.63A 3asoA-2pncA:
undetectable		 3asoA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.62A 3asoN-2pncA:
undetectable		 3asoN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.76A 3bvdA-2pncA:
undetectable		 3bvdA-2pncA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 8 GLY A 482
ASN A 481
PHE A 703
TYR A 479
 None
CL  A 807 (-3.9A)
None
None
 1.35A 3ccfA-2pncA:
undetectable		 3ccfA-2pncA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 6 PHE A 414
ALA A 342
GLY A 391
TYR A 392
 None
 1.02A 3dd1A-2pncA:
undetectable		 3dd1A-2pncA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 6 PHE A 414
ALA A 342
GLY A 391
TYR A 392
 None
 0.97A 3dd1B-2pncA:
undetectable		 3dd1B-2pncA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 6 PHE A 414
ALA A 342
GLY A 391
TYR A 392
 None
 0.99A 3ddsB-2pncA:
undetectable		 3ddsB-2pncA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 6 PHE A 414
ALA A 342
GLY A 391
TYR A 392
 None
 1.01A 3ddwB-2pncA:
undetectable		 3ddwB-2pncA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.69A 3dtuA-2pncA:
undetectable		 3dtuA-2pncA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.69A 3dtuC-2pncA:
undetectable		 3dtuC-2pncA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 ILE A 290
PHE A 498
HIS A 196
 None
 0.56A 3h0aA-2pncA:
undetectable		 3h0aA-2pncA:
14.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 519
HIS A 521
HIS A 683
 CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
CU  A 804 (-3.2A)
 0.21A 3hiiA-2pncA:
47.2		 3hiiA-2pncA:
40.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 519
HIS A 521
HIS A 683
 CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
CU  A 804 (-3.2A)
 0.21A 3hiiB-2pncA:
46.3		 3hiiB-2pncA:
40.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 TRP A 474
ALA A 427
VAL A 464
 None
 0.95A 3l8lC-2pncA:
undetectable
3l8lD-2pncA:
undetectable		 3l8lC-2pncA:
3.08
3l8lD-2pncA:
2.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 5 ILE A 290
MET A 210
ASN A 211
PHE A 498
 None
 1.22A 3octA-2pncA:
undetectable		 3octA-2pncA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S33_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.71A 3s33A-2pncA:
undetectable		 3s33A-2pncA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.72A 3s38A-2pncA:
undetectable		 3s38A-2pncA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S39_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.67A 3s39A-2pncA:
undetectable		 3s39A-2pncA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.77A 3s3aA-2pncA:
undetectable		 3s3aA-2pncA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3B_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.71A 3s3bA-2pncA:
undetectable		 3s3bA-2pncA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3C_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.72A 3s3cA-2pncA:
undetectable		 3s3cA-2pncA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3D_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.65A 3s3dA-2pncA:
undetectable		 3s3dA-2pncA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		5 / 12 GLY A 387
ARG A 622
GLY A 368
ALA A 623
SER A 618
 None
 1.05A 3sudA-2pncA:
undetectable		 3sudA-2pncA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		5 / 12 VAL A 351
ASP A 350
GLY A 115
ALA A 108
ALA A 107
 None
 0.97A 3sudD-2pncA:
undetectable		 3sudD-2pncA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		5 / 12 VAL A 351
ASP A 350
GLY A 115
ALA A 108
ALA A 107
 None
 0.97A 3sueC-2pncA:
undetectable		 3sueC-2pncA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		5 / 12 GLY A 387
ARG A 622
GLY A 368
ALA A 623
SER A 618
 None
 1.15A 3sueD-2pncA:
undetectable		 3sueD-2pncA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		5 / 12 VAL A 351
ASP A 350
GLY A 115
ALA A 108
ALA A 107
 None
 1.00A 3sufD-2pncA:
undetectable		 3sufD-2pncA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TF1_A_ACTA191_0
(METHYL-ACCEPTING
CHEMOTAXIS PROTEIN)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 5 THR A 209
ILE A 228
PHE A 183
LEU A 246
 None
 1.25A 3tf1A-2pncA:
0.5		 3tf1A-2pncA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 ASN A 211
ALA A 213
ARG A 215
 None
 0.75A 3tj7C-2pncA:
undetectable
3tj7D-2pncA:
undetectable		 3tj7C-2pncA:
14.27
3tj7D-2pncA:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 8 ILE A 182
LEU A 187
VAL A 242
GLY A 243
 None
 0.75A 3w1wA-2pncA:
undetectable		 3w1wA-2pncA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		5 / 12 PHE A 609
ILE A 494
ASP A 689
PHE A 681
HIS A 521
 None
TPQ  A 470 ( 4.8A)
None
None
CU  A 804 ( 3.3A)
 1.43A 3welA-2pncA:
2.9		 3welA-2pncA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.61A 3wg7A-2pncA:
undetectable		 3wg7A-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.62A 3wg7N-2pncA:
undetectable		 3wg7N-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.61A 3x2qA-2pncA:
undetectable		 3x2qA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.65A 3x2qN-2pncA:
undetectable		 3x2qN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 GLY A 220
SER A 219
TRP A 653
 None
 0.80A 4e7cD-2pncA:
undetectable		 4e7cD-2pncA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 4 ILE A 362
SER A 363
ASP A 530
ASP A 113
 None
None
CA  A 805 (-3.5A)
None
 1.46A 4krhB-2pncA:
undetectable		 4krhB-2pncA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 6 GLN A 101
VAL A 154
THR A 155
ARG A 158
 None
 0.97A 4lnxA-2pncA:
undetectable		 4lnxA-2pncA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 6 GLU A  99
VAL A 154
THR A 155
ARG A 158
 None
 1.36A 4lnxA-2pncA:
undetectable		 4lnxA-2pncA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		5 / 12 ASP A 385
TRP A 626
THR A 678
ALA A 679
TRP A 474
 CLU  A 808 (-3.1A)
None
None
None
None
 1.40A 4u15A-2pncA:
undetectable		 4u15A-2pncA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 SER A 386
GLU A 361
GLU A 638
 None
 0.80A 4ymgB-2pncA:
undetectable		 4ymgB-2pncA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.60A 5b1aA-2pncA:
undetectable		 5b1aA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.62A 5b1aN-2pncA:
undetectable		 5b1aN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.62A 5b1bA-2pncA:
undetectable		 5b1bA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.62A 5b1bN-2pncA:
undetectable		 5b1bN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.61A 5b3sA-2pncA:
undetectable		 5b3sA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.62A 5b3sN-2pncA:
undetectable		 5b3sN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		4 / 6 LYS A 471
TYR A 472
TYR A 525
LEU A 364
 CLU  A 808 (-3.7A)
CLU  A 808 (-3.4A)
None
None
 1.27A 5bmvB-2pncA:
undetectable		 5bmvB-2pncA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.63A 5iy5A-2pncA:
undetectable		 5iy5A-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.62A 5iy5N-2pncA:
undetectable		 5iy5N-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		5 / 12 GLY A 143
ASP A 153
VAL A 154
THR A 155
LEU A 124
 None
 0.76A 5kocA-2pncA:
undetectable		 5kocA-2pncA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.69A 5w97a-2pncA:
undetectable		 5w97a-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.67A 5waua-2pncA:
undetectable		 5waua-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.64A 5x19A-2pncA:
undetectable		 5x19A-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.65A 5x19N-2pncA:
undetectable		 5x19N-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.67A 5x1bA-2pncA:
undetectable		 5x1bA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.65A 5x1bN-2pncA:
undetectable		 5x1bN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.68A 5x1fA-2pncA:
undetectable		 5x1fA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.66A 5x1fN-2pncA:
undetectable		 5x1fN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.65A 5xdqA-2pncA:
undetectable		 5xdqA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.66A 5xdqN-2pncA:
undetectable		 5xdqN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.65A 5xdxA-2pncA:
undetectable		 5xdxA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.66A 5xdxN-2pncA:
undetectable		 5xdxN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.60A 5z84A-2pncA:
undetectable		 5z84A-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.63A 5z84N-2pncA:
undetectable		 5z84N-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.63A 5z85A-2pncA:
undetectable		 5z85A-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.62A 5z85N-2pncA:
undetectable		 5z85N-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.63A 5z86A-2pncA:
undetectable		 5z86A-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.68A 5z86N-2pncA:
undetectable		 5z86N-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.62A 5zcoA-2pncA:
undetectable		 5zcoA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.59A 5zcoN-2pncA:
undetectable		 5zcoN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.60A 5zcpA-2pncA:
undetectable		 5zcpA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.63A 5zcpN-2pncA:
undetectable		 5zcpN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.60A 5zcqA-2pncA:
undetectable		 5zcqA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.60A 5zcqN-2pncA:
undetectable		 5zcqN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_1
(ALPHA-AMYLASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 TYR A 150
ALA A 125
LEU A 124
 None
 0.64A 6ag0C-2pncA:
undetectable		 6ag0C-2pncA:
8.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		5 / 12 VAL A 351
ASP A 350
GLY A 115
ALA A 108
ALA A 107
 None
 0.95A 6c2mC-2pncA:
undetectable		 6c2mC-2pncA:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.74A 6hu9a-2pncA:
undetectable		 6hu9a-2pncA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_H_PCFH604_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		5 / 8 PHE A 624
HIS A 524
GLY A 680
SER A 522
ALA A 369
 None
None
None
None
CLU  A 808 (-3.4A)
 1.14A 6hu9H-2pncA:
undetectable
6hu9e-2pncA:
undetectable		 6hu9H-2pncA:
9.17
6hu9e-2pncA:
12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.73A 6hu9m-2pncA:
undetectable		 6hu9m-2pncA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.63A 6nknA-2pncA:
undetectable		 6nknA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.63A 6nknN-2pncA:
undetectable		 6nknN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.65A 6nmfA-2pncA:
undetectable		 6nmfA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.70A 6nmfN-2pncA:
undetectable		 6nmfN-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.71A 6nmpA-2pncA:
undetectable		 6nmpA-2pncA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME
(Bos
taurus) 		3 / 3 HIS A 683
HIS A 519
HIS A 521
 CU  A 804 (-3.2A)
CU  A 804 (-3.3A)
CU  A 804 ( 3.3A)
 0.68A 6nmpN-2pncA:
undetectable		 6nmpN-2pncA:
20.73