SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pnd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RK3_A_VDXA500_2 (VITAMIN D3 RECEPTOR)	2pnd	V-SET AND IMMUNOGLOBULIN DOMAIN CONTAINING 4 (Mus musculus)	4 / 4	LEU A 84 ILE A 58 ARG A 64 TYR A 92	None	1.29A	1rk3A-2pndA: undetectable	1rk3A-2pndA: 17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HC4_A_VDXA525_2 (VITAMIN D RECEPTOR)	2pnd	V-SET AND IMMUNOGLOBULIN DOMAIN CONTAINING 4 (Mus musculus)	4 / 7	LEU A 84 ILE A 58 ARG A 64 TYR A 92	None	1.22A	2hc4A-2pndA: undetectable	2hc4A-2pndA: 15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZLC_A_VDXA500_2 (VITAMIN D3 RECEPTOR)	2pnd	V-SET AND IMMUNOGLOBULIN DOMAIN CONTAINING 4 (Mus musculus)	4 / 5	LEU A 84 ILE A 58 ARG A 64 TYR A 92	None	1.30A	2zlcA-2pndA: undetectable	2zlcA-2pndA: 18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6J20_A_GBQA1201_1 (SUBSTANCE-P RECEPTOR,ENDOLYSIN)	2pnd	V-SET AND IMMUNOGLOBULIN DOMAIN CONTAINING 4 (Mus musculus)	4 / 7	ILE A 48 GLN A 60 HIS A 41 VAL A 39	None	1.19A	6j20A-2pndA: undetectable	6j20A-2pndA: 13.48

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RK3_A_VDXA500_2","VITAMIN D3 RECEPTOR","2pnd","V-SET AND IMMUNOGLOBULIN DOMAIN CONTAINING 4","Mus musculus",4,"LEU A  84;ILE A  58;ARG A  64;TYR A  92","None","1.29A","1rk3A-2pndA:undetectable","1rk3A-2pndA:17.73"],["2HC4_A_VDXA525_2","VITAMIN D RECEPTOR","2pnd","V-SET AND IMMUNOGLOBULIN DOMAIN CONTAINING 4","Mus musculus",4,"LEU A  84;ILE A  58;ARG A  64;TYR A  92","None","1.22A","2hc4A-2pndA:undetectable","2hc4A-2pndA:15.58"],["2ZLC_A_VDXA500_2","VITAMIN D3 RECEPTOR","2pnd","V-SET AND IMMUNOGLOBULIN DOMAIN CONTAINING 4","Mus musculus",4,"LEU A  84;ILE A  58;ARG A  64;TYR A  92","None","1.30A","2zlcA-2pndA:undetectable","2zlcA-2pndA:18.01"],["6J20_A_GBQA1201_1","SUBSTANCE-P RECEPTOR,ENDOLYSIN","2pnd","V-SET AND IMMUNOGLOBULIN DOMAIN CONTAINING 4","Mus musculus",4,"ILE A  48;GLN A  60;HIS A  41;VAL A  39","None","1.19A","6j20A-2pndA:undetectable","6j20A-2pndA:13.48"]]