SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2poi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 2poi BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 4
(Homo
sapiens) 		3 / 3 ALA A  68
VAL A  61
TRP A  73
 None
 0.89A 1nt6A-2poiA:
undetectable		 1nt6A-2poiA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 2poi BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 4
(Homo
sapiens) 		3 / 3 ALA A  68
VAL A  61
TRP A  73
 None
 0.89A 1nt6B-2poiA:
undetectable		 1nt6B-2poiA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 2poi BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 4
(Homo
sapiens) 		3 / 3 TRP A  73
ALA A  44
VAL A  42
 None
 0.85A 2izqA-2poiA:
undetectable
2izqB-2poiA:
undetectable		 2izqA-2poiA:
8.05
2izqB-2poiA:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 2poi BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 4
(Homo
sapiens) 		4 / 7 GLY A  58
THR A  60
TRP A  73
SER A  40
 None
 1.20A 2o5yH-2poiA:
undetectable
2o5yL-2poiA:
undetectable		 2o5yH-2poiA:
18.84
2o5yL-2poiA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 2poi BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 4
(Homo
sapiens) 		3 / 3 PRO A  37
GLY A  58
TYR A  54
 None
 0.72A 2vouA-2poiA:
undetectable		 2vouA-2poiA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 2poi BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 4
(Homo
sapiens) 		3 / 3 PRO A  37
GLY A  58
TYR A  54
 None
 0.70A 2vouB-2poiA:
undetectable		 2vouB-2poiA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 2poi BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 4
(Homo
sapiens) 		3 / 3 PRO A  37
GLY A  58
TYR A  54
 None
 0.70A 2vouC-2poiA:
undetectable		 2vouC-2poiA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_2
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 2poi BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 4
(Homo
sapiens) 		4 / 4 VAL A  61
ARG A  49
ILE A  93
THR A  32
 None
 1.19A 3cl9A-2poiA:
undetectable		 3cl9A-2poiA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 2poi BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 4
(Homo
sapiens) 		3 / 3 ARG A  72
ASP A  77
ASP A  71
 None
 0.72A 3jayA-2poiA:
undetectable		 3jayA-2poiA:
6.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 2poi BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 4
(Homo
sapiens) 		3 / 3 ARG A  72
ASP A  77
ASP A  71
 None
 0.79A 3jb2A-2poiA:
undetectable		 3jb2A-2poiA:
6.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 2poi BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 4
(Homo
sapiens) 		3 / 3 ARG A  82
ASP A  59
ASP A  77
 None
 0.92A 3jb2A-2poiA:
undetectable		 3jb2A-2poiA:
6.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 2poi BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 4
(Homo
sapiens) 		3 / 3 ARG A  72
ASP A  77
ASP A  71
 None
 0.86A 3jb3A-2poiA:
undetectable		 3jb3A-2poiA:
6.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 2poi BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 4
(Homo
sapiens) 		3 / 3 ALA A  44
VAL A  42
TRP A  73
 None
 0.81A 3l8lA-2poiA:
undetectable
3l8lB-2poiA:
undetectable		 3l8lA-2poiA:
8.05
3l8lB-2poiA:
8.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 2poi BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 4
(Homo
sapiens) 		3 / 3 ALA A  44
VAL A  42
TRP A  73
 None
 0.85A 3l8lC-2poiA:
undetectable
3l8lD-2poiA:
undetectable		 3l8lC-2poiA:
8.05
3l8lD-2poiA:
8.24