SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2por'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		 2por PORIN
(Rhodobacter
capsulatus) 		4 / 7 ASP A  93
ASP A  95
TYR A  87
TYR A 248
 CA  A 303 (-2.1A)
CA  A 303 (-2.2A)
None
None
 1.44A 1cebB-2porA:
undetectable		 1cebB-2porA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 2por PORIN
(Rhodobacter
capsulatus) 		4 / 4 GLY A  90
GLY A 280
GLY A 266
GLY A 279
 None
C8E  A 546 (-3.9A)
C8E  A 546 ( 4.4A)
C8E  A 546 ( 4.3A)
 0.65A 3bogD-2porA:
undetectable		 3bogD-2porA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 2por PORIN
(Rhodobacter
capsulatus) 		5 / 12 GLY A  77
GLY A 107
ALA A 132
ALA A 131
LEU A 120
 None
 0.95A 3p2kD-2porA:
undetectable		 3p2kD-2porA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_1
(HIV-1 PROTEASE)		 2por PORIN
(Rhodobacter
capsulatus) 		5 / 11 GLY A 247
VAL A 278
GLY A 279
GLY A 280
ILE A 281
 None
None
C8E  A 546 ( 4.3A)
C8E  A 546 (-3.9A)
C8E  A 546 ( 4.9A)
 0.89A 3ufnA-2porA:
undetectable		 3ufnA-2porA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 2por PORIN
(Rhodobacter
capsulatus) 		3 / 3 ASP A 136
GLU A 141
GLY A 140
 CA  A 304 (-2.1A)
None
CA  A 304 (-4.3A)
 0.69A 3w9tA-2porA:
undetectable		 3w9tA-2porA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BB2_B_STRB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2por PORIN
(Rhodobacter
capsulatus) 		5 / 11 ALA A 132
SER A 133
PHE A  67
ILE A  70
SER A  64
 None
 1.41A 4bb2A-2porA:
undetectable
4bb2B-2porA:
undetectable		 4bb2A-2porA:
23.63
4bb2B-2porA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2por PORIN
(Rhodobacter
capsulatus) 		4 / 8 ASP A  85
ASP A  74
ASP A  58
ASP A 108
 CA  A 302 ( 4.3A)
None
None
CA  A 302 (-3.3A)
 0.96A 4feuD-2porA:
undetectable		 4feuD-2porA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2por PORIN
(Rhodobacter
capsulatus) 		4 / 6 ASP A 108
ASP A  93
ASP A 101
GLU A  80
 CA  A 302 (-3.3A)
CA  A 303 (-2.1A)
CA  A 303 (-2.9A)
CA  A 302 (-2.2A)
 1.27A 4gkhJ-2porA:
undetectable		 4gkhJ-2porA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2por PORIN
(Rhodobacter
capsulatus) 		4 / 8 ASP A  74
ASP A 108
ASP A  93
ASP A 101
 None
CA  A 302 (-3.3A)
CA  A 303 (-2.1A)
CA  A 303 (-2.9A)
 1.06A 4gkhC-2porA:
undetectable
4gkhK-2porA:
undetectable		 4gkhC-2porA:
23.48
4gkhK-2porA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2por PORIN
(Rhodobacter
capsulatus) 		4 / 8 ASP A  74
ASP A 108
ASP A  93
ASP A 101
 None
CA  A 302 (-3.3A)
CA  A 303 (-2.1A)
CA  A 303 (-2.9A)
 1.02A 4gkiE-2porA:
undetectable
4gkiG-2porA:
undetectable		 4gkiE-2porA:
23.48
4gkiG-2porA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 2por PORIN
(Rhodobacter
capsulatus) 		5 / 9 ASP A  93
VAL A 292
ALA A 293
GLY A  99
GLY A 280
 CA  A 303 (-2.1A)
None
C8E  A 546 ( 4.2A)
None
C8E  A 546 (-3.9A)
 1.36A 4mmfA-2porA:
undetectable		 4mmfA-2porA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 2por PORIN
(Rhodobacter
capsulatus) 		5 / 9 ASP A  93
VAL A 292
ALA A 293
GLY A  99
GLY A 280
 CA  A 303 (-2.1A)
None
C8E  A 546 ( 4.2A)
None
C8E  A 546 (-3.9A)
 1.36A 4mmfB-2porA:
undetectable		 4mmfB-2porA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 2por PORIN
(Rhodobacter
capsulatus) 		4 / 6 SER A  32
GLU A   1
GLY A  73
GLY A  59
 None
 0.86A 5cdnC-2porA:
undetectable
5cdnD-2porA:
undetectable		 5cdnC-2porA:
20.30
5cdnD-2porA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 2por PORIN
(Rhodobacter
capsulatus) 		4 / 6 SER A  32
GLU A   1
GLY A  73
GLY A  59
 None
 0.90A 5cdnT-2porA:
undetectable
5cdnU-2porA:
undetectable		 5cdnT-2porA:
20.30
5cdnU-2porA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2por PORIN
(Rhodobacter
capsulatus) 		3 / 3 GLY A 233
THR A 106
PRO A 103
 C8E  A 548 ( 4.4A)
None
None
 0.61A 5v5zA-2porA:
undetectable		 5v5zA-2porA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_1
(MRNA CAPPING ENZYME
P5)		 2por PORIN
(Rhodobacter
capsulatus) 		3 / 3 TYR A 232
ASP A 203
ASP A 253
 C8E  A 548 (-4.8A)
None
None
 0.69A 5x6yA-2porA:
undetectable		 5x6yA-2porA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC607_0
(ALPHA-AMYLASE)		 2por PORIN
(Rhodobacter
capsulatus) 		4 / 6 GLY A  52
ASP A 115
GLY A  59
GLY A  73
 None
 0.69A 6ag0C-2porA:
undetectable		 6ag0C-2porA:
14.88