SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2poy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 2poy PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Cryptosporidium
parvum) 		3 / 3 TYR A  71
GLY A  73
PHE A  90
 None
 0.67A 2m2pB-2poyA:
undetectable		 2m2pB-2poyA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_2
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 2poy PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Cryptosporidium
parvum) 		4 / 6 ILE A  80
PRO A  81
ILE A  28
VAL A 179
 None
 0.97A 4zj8A-2poyA:
undetectable		 4zj8A-2poyA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 2poy PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Cryptosporidium
parvum) 		5 / 12 GLY A 132
ILE A 101
ASN A 125
PHE A  52
LEU A 121
 None
 0.98A 5fa8A-2poyA:
undetectable		 5fa8A-2poyA:
20.40