SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ppt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)		 2ppt THIOREDOXIN-2
(Rhodobacter
capsulatus) 		4 / 8 ALA A  57
LEU A  15
LEU A  64
ALA A  97
 None
 0.74A 1e7cA-2pptA:
undetectable		 1e7cA-2pptA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 2ppt THIOREDOXIN-2
(Rhodobacter
capsulatus) 		5 / 9 LEU A  28
ILE A  42
GLY A  31
LEU A  10
SER A   9
 None
 1.13A 3ai9X-2pptA:
undetectable		 3ai9X-2pptA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 2ppt THIOREDOXIN-2
(Rhodobacter
capsulatus) 		4 / 8 PHE A 122
VAL A  94
LEU A 148
PRO A  63
 None
 1.10A 3bgdB-2pptA:
undetectable		 3bgdB-2pptA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2J_C_NIOC311_1
(ALPHA/BETA-HYDROLASE
-LIKE PROTEIN)		 2ppt THIOREDOXIN-2
(Rhodobacter
capsulatus) 		5 / 12 PHE A 119
LEU A 140
ASP A  67
ALA A 134
CYH A  76
 None
 1.49A 3r2jC-2pptA:
undetectable		 3r2jC-2pptA:
24.41