SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pqd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.41A 1c9sD-2pqdA:
undetectable
1c9sE-2pqdA:
undetectable
1c9sD-2pqdA:
10.20
1c9sE-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CRB_A_RTLA200_0
(CELLULAR RETINOL
BINDING PROTEIN)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 LEU A 257
LEU A 311
ALA A 334
LEU A 331
ILE A  24
None
0.92A 1crbA-2pqdA:
undetectable
1crbA-2pqdA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 8 THR A  59
GLY A  38
PHE A  35
ARG A  33
None
None
None
GG9  A 501 (-2.8A)
0.74A 1d0vA-2pqdA:
undetectable
1d0vA-2pqdA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 8 ALA A 445
LEU A  18
LEU A 415
ALA A 254
None
0.55A 1e7cA-2pqdA:
undetectable
1e7cA-2pqdA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.44A 1gtfI-2pqdA:
undetectable
1gtfJ-2pqdA:
undetectable
1gtfI-2pqdA:
10.20
1gtfJ-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.36A 1gtfM-2pqdA:
0.0
1gtfN-2pqdA:
0.0
1gtfM-2pqdA:
10.20
1gtfN-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 1gtfP-2pqdA:
undetectable
1gtfQ-2pqdA:
undetectable
1gtfP-2pqdA:
10.20
1gtfQ-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.32A 1gtfT-2pqdA:
undetectable
1gtfU-2pqdA:
undetectable
1gtfT-2pqdA:
10.20
1gtfU-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 11 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.34A 1gtfU-2pqdA:
undetectable
1gtfV-2pqdA:
undetectable
1gtfU-2pqdA:
10.20
1gtfV-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.33A 1gtfL-2pqdA:
undetectable
1gtfV-2pqdA:
undetectable
1gtfL-2pqdA:
10.20
1gtfV-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 1gtnN-2pqdA:
undetectable
1gtnO-2pqdA:
undetectable
1gtnN-2pqdA:
10.20
1gtnO-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.31A 1gtnO-2pqdA:
undetectable
1gtnP-2pqdA:
undetectable
1gtnO-2pqdA:
10.20
1gtnP-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 11 VAL A  82
GLY A  86
LEU A  88
TYR A 113
GLY A  39
None
1.28A 1iolA-2pqdA:
undetectable
1iolA-2pqdA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 8 THR A  59
GLY A  38
PHE A  35
ARG A  33
None
None
None
GG9  A 501 (-2.8A)
0.70A 1jhaA-2pqdA:
undetectable
1jhaA-2pqdA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 GLY A 209
GLY A  38
PHE A  37
LEU A 234
GLY A 236
None
1.19A 1jhoA-2pqdA:
undetectable
1jhoA-2pqdA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHQ_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 8 GLY A 209
GLY A  38
PHE A  37
LEU A 234
GLY A 236
None
1.17A 1jhqA-2pqdA:
undetectable
1jhqA-2pqdA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHQ_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 8 THR A  59
GLY A  38
PHE A  35
ARG A  33
None
None
None
GG9  A 501 (-2.8A)
0.73A 1jhqA-2pqdA:
undetectable
1jhqA-2pqdA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 GLY A 209
GLY A  38
PHE A  37
LEU A 234
GLY A 236
None
1.16A 1jhrA-2pqdA:
undetectable
1jhrA-2pqdA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHV_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 8 THR A  59
GLY A  38
PHE A  35
ARG A  33
None
None
None
GG9  A 501 (-2.8A)
0.72A 1jhvA-2pqdA:
undetectable
1jhvA-2pqdA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 GLY A 209
GLY A  38
PHE A  37
LEU A 234
GLY A 236
None
1.19A 1l5kA-2pqdA:
undetectable
1l5kA-2pqdA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 GLY A 209
GLY A  38
PHE A  37
LEU A 234
GLY A 236
None
1.20A 1l5lA-2pqdA:
undetectable
1l5lA-2pqdA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 GLY A 209
GLY A  38
PHE A  37
LEU A 234
GLY A 236
None
1.21A 1l5mA-2pqdA:
undetectable
1l5mA-2pqdA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.38A 1utdN-2pqdA:
undetectable
1utdO-2pqdA:
undetectable
1utdN-2pqdA:
10.20
1utdO-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.31A 1utdQ-2pqdA:
undetectable
1utdR-2pqdA:
undetectable
1utdQ-2pqdA:
10.20
1utdR-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 1utdR-2pqdA:
undetectable
1utdS-2pqdA:
undetectable
1utdR-2pqdA:
10.20
1utdS-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 5 ILE A  79
PHE A 210
PHE A  37
ILE A 239
None
1.02A 2hjhA-2pqdA:
undetectable
2hjhA-2pqdA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_C_MTXC613_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 VAL A  56
LEU A 125
SER A  29
ARG A  33
THR A 431
None
None
GG9  A 501 (-2.6A)
GG9  A 501 (-2.8A)
None
1.13A 2oipC-2pqdA:
2.0
2oipC-2pqdA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_H_CPFH1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
3 / 3 ARG A  13
GLU A 448
SER A 261
None
0.90A 2xctD-2pqdA:
undetectable
2xctD-2pqdA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 11 LEU A 228
LEU A 207
SER A  42
LEU A 234
LEU A 182
None
1.10A 2xn5A-2pqdA:
undetectable
2xn5A-2pqdA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_1
(ADENOSYLHOMOCYSTEINA
SE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 LEU A 269
THR A 275
GLU A 299
LYS A 205
ASP A 201
None
1.48A 2zj0A-2pqdA:
undetectable
2zj0A-2pqdA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_1
(ADENOSYLHOMOCYSTEINA
SE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.19A 2zj0A-2pqdA:
undetectable
2zj0A-2pqdA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_1
(ADENOSYLHOMOCYSTEINA
SE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.14A 2zj0B-2pqdA:
undetectable
2zj0B-2pqdA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_1
(ADENOSYLHOMOCYSTEINA
SE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.16A 2zj0C-2pqdA:
undetectable
2zj0C-2pqdA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_D_2FAD500_1
(ADENOSYLHOMOCYSTEINA
SE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.17A 2zj0D-2pqdA:
undetectable
2zj0D-2pqdA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 LEU A 269
THR A 275
GLU A 299
LYS A 205
ASP A 201
None
1.46A 3ce6A-2pqdA:
undetectable
3ce6A-2pqdA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.23A 3ce6A-2pqdA:
undetectable
3ce6A-2pqdA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_1
(ADENOSYLHOMOCYSTEINA
SE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.20A 3ce6B-2pqdA:
undetectable
3ce6B-2pqdA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 LEU A 269
THR A 275
GLU A 299
LYS A 205
ASP A 201
None
1.41A 3ce6C-2pqdA:
undetectable
3ce6C-2pqdA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.19A 3ce6C-2pqdA:
undetectable
3ce6C-2pqdA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.20A 3ce6D-2pqdA:
undetectable
3ce6D-2pqdA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 ALA A 183
GLY A 108
LEU A 185
LEU A 181
SER A 178
None
None
None
None
GG9  A 501 ( 4.8A)
1.10A 3g2oA-2pqdA:
undetectable
3g2oA-2pqdA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 6 MET A 270
VAL A 268
LEU A  50
ILE A 278
ILE A 265
None
1.27A 3gcsA-2pqdA:
undetectable
3gcsA-2pqdA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 6 SER A  34
LEU A  87
ILE A  79
LEU A 105
None
0.94A 3kk6A-2pqdA:
undetectable
3kk6A-2pqdA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_B_EAAB222_1
(GLUTATHIONE
S-TRANSFERASE P)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 PHE A 410
VAL A 421
VAL A 333
ASN A 392
GLY A 391
None
1.47A 3km6B-2pqdA:
undetectable
3km6B-2pqdA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_1
(ADENOSYLHOMOCYSTEINA
SE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.38A 3ondA-2pqdA:
undetectable
3ondA-2pqdA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_1
(ADENOSYLHOMOCYSTEINA
SE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.36A 3ondB-2pqdA:
undetectable
3ondB-2pqdA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_1
(HIV-1 PROTEASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 11 ARG A 357
LEU A 350
ALA A 321
ASP A 319
ILE A 197
GG9  A 501 (-2.6A)
None
None
None
None
1.14A 3spkA-2pqdA:
undetectable
3spkA-2pqdA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
3 / 3 TYR A 328
LEU A 367
LYS A 366
None
0.71A 3sueD-2pqdA:
undetectable
3sueD-2pqdA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
3 / 3 TYR A 328
LEU A 402
ARG A 405
None
None
GG9  A 501 (-3.9A)
0.75A 3sufB-2pqdA:
undetectable
3sufB-2pqdA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 8 PRO A 329
VAL A 333
LEU A 365
ILE A 406
None
0.90A 3u5kA-2pqdA:
undetectable
3u5kA-2pqdA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_B_08JB2_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 7 PRO A 329
VAL A 333
LEU A 365
ILE A 406
None
0.92A 3u5kB-2pqdA:
undetectable
3u5kB-2pqdA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 8 PRO A 329
VAL A 333
LEU A 365
ILE A 406
None
0.90A 3u5kC-2pqdA:
undetectable
3u5kC-2pqdA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 8 PRO A 329
VAL A 333
LEU A 365
ILE A 406
None
0.81A 3u5kD-2pqdA:
undetectable
3u5kD-2pqdA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_D_T1CD401_1
(TETX2 PROTEIN)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 ASP A 244
MET A 206
ASN A 271
GLY A 298
GLY A  26
None
1.39A 3v3oD-2pqdA:
0.5
3v3oD-2pqdA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 ARG A 138
GLY A 158
MET A 107
GLY A 108
THR A 187
None
1.30A 3wg7G-2pqdA:
0.0
3wg7N-2pqdA:
0.0
3wg7O-2pqdA:
0.0
3wg7G-2pqdA:
11.01
3wg7N-2pqdA:
22.22
3wg7O-2pqdA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 11 MET A 107
GLY A 108
THR A 187
ARG A 138
GLY A 158
None
1.34A 3x2qA-2pqdA:
0.0
3x2qB-2pqdA:
0.0
3x2qT-2pqdA:
0.0
3x2qA-2pqdA:
22.22
3x2qB-2pqdA:
18.30
3x2qT-2pqdA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFU_A_KANA401_1
(APH(2')-ID)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 SER A  29
ASP A  27
ASP A 326
GLU A 299
GLU A 204
GG9  A 501 (-2.6A)
None
GG9  A 501 (-2.6A)
None
None
1.46A 4dfuA-2pqdA:
0.1
4dfuA-2pqdA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_A_REAA501_1
(RETINOIC ACID
RECEPTOR BETA)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 11 LEU A 252
ILE A 265
SER A 309
LEU A 439
ILE A 330
None
1.08A 4dm8A-2pqdA:
undetectable
4dm8A-2pqdA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 VAL A  56
SER A  29
LEU A 105
ARG A  33
THR A 431
None
GG9  A 501 (-2.6A)
None
GG9  A 501 (-2.8A)
None
1.46A 4eilB-2pqdA:
undetectable
4eilB-2pqdA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 7 PHE A 210
GLY A  39
THR A  45
ILE A 239
None
0.92A 4ejjA-2pqdA:
undetectable
4ejjA-2pqdA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 GLY A 209
GLY A  38
PHE A  37
LEU A 234
GLY A 236
None
1.19A 4kqiA-2pqdA:
undetectable
4kqiA-2pqdA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 LEU A 269
THR A 275
GLU A 299
LYS A 205
ASP A 201
None
1.49A 4lvcA-2pqdA:
undetectable
4lvcA-2pqdA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.32A 4lvcA-2pqdA:
undetectable
4lvcA-2pqdA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.38A 4lvcB-2pqdA:
undetectable
4lvcB-2pqdA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.37A 4lvcC-2pqdA:
undetectable
4lvcC-2pqdA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 LEU A 281
ILE A 330
VAL A 412
LEU A 415
LEU A 252
None
0.95A 4m11A-2pqdA:
undetectable
4m11A-2pqdA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 ILE A 330
VAL A 412
LEU A 415
ALA A 255
LEU A 252
None
1.03A 4m11B-2pqdA:
undetectable
4m11B-2pqdA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 LEU A 281
ILE A 330
VAL A 412
ALA A 255
LEU A 252
None
1.10A 4o1zB-2pqdA:
undetectable
4o1zB-2pqdA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.39A 4pfjA-2pqdA:
undetectable
4pfjA-2pqdA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 LEU A 228
LEU A 207
SER A  42
LEU A 234
LEU A 182
None
1.14A 4yiaA-2pqdA:
undetectable
4yiaA-2pqdA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 SER A 261
LEU A 277
LEU A 281
SER A 308
LEU A 256
None
1.20A 4yiaA-2pqdA:
undetectable
4yiaA-2pqdA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.36A 5axaA-2pqdA:
undetectable
5axaA-2pqdA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.38A 5axaC-2pqdA:
undetectable
5axaC-2pqdA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_1
(ADENOSYLHOMOCYSTEINA
SE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.38A 5axdA-2pqdA:
undetectable
5axdA-2pqdA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_1
(ADENOSYLHOMOCYSTEINA
SE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.38A 5axdC-2pqdA:
undetectable
5axdC-2pqdA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 ALA A  12
PRO A 420
GLY A 414
GLY A 391
ALA A 254
None
1.20A 5c0oE-2pqdA:
undetectable
5c0oE-2pqdA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_1
(UNCHARACTERIZED
PROTEIN MJ0489)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 4 LYS A 177
ASP A  27
GLU A 204
THR A 199
None
0.98A 5d4uA-2pqdA:
0.3
5d4uA-2pqdA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_1
(UNCHARACTERIZED
PROTEIN MJ0489)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 4 LYS A 177
ASP A  27
GLU A 204
THR A 199
None
1.00A 5d4uB-2pqdA:
0.0
5d4uB-2pqdA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_1
(UNCHARACTERIZED
PROTEIN MJ0489)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 4 LYS A 177
ASP A  27
GLU A 204
THR A 199
None
1.05A 5d4uC-2pqdA:
0.5
5d4uC-2pqdA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN MJ0489)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 4 LYS A 177
ASP A  27
GLU A 204
THR A 199
None
0.97A 5d4uD-2pqdA:
0.5
5d4uD-2pqdA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.42A 5eeuE-2pqdA:
undetectable
5eeuF-2pqdA:
undetectable
5eeuE-2pqdA:
10.20
5eeuF-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.34A 5eeuL-2pqdA:
0.0
5eeuM-2pqdA:
0.0
5eeuL-2pqdA:
10.20
5eeuM-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.35A 5eeuM-2pqdA:
0.0
5eeuN-2pqdA:
0.0
5eeuM-2pqdA:
10.20
5eeuN-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.31A 5eeuN-2pqdA:
undetectable
5eeuO-2pqdA:
undetectable
5eeuN-2pqdA:
10.20
5eeuO-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 5eeuP-2pqdA:
undetectable
5eeuQ-2pqdA:
undetectable
5eeuP-2pqdA:
10.20
5eeuQ-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 5eeuR-2pqdA:
undetectable
5eeuS-2pqdA:
undetectable
5eeuR-2pqdA:
10.20
5eeuS-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 5eeuS-2pqdA:
undetectable
5eeuT-2pqdA:
undetectable
5eeuS-2pqdA:
10.20
5eeuT-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.36A 5eeuT-2pqdA:
undetectable
5eeuU-2pqdA:
undetectable
5eeuT-2pqdA:
10.20
5eeuU-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 5eeuU-2pqdA:
undetectable
5eeuV-2pqdA:
undetectable
5eeuU-2pqdA:
10.20
5eeuV-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.41A 5eevE-2pqdA:
undetectable
5eevF-2pqdA:
undetectable
5eevE-2pqdA:
10.20
5eevF-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.35A 5eevL-2pqdA:
0.0
5eevM-2pqdA:
0.0
5eevL-2pqdA:
10.20
5eevM-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.35A 5eevM-2pqdA:
0.0
5eevN-2pqdA:
0.0
5eevM-2pqdA:
10.20
5eevN-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.31A 5eevN-2pqdA:
undetectable
5eevO-2pqdA:
undetectable
5eevN-2pqdA:
10.20
5eevO-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.32A 5eevP-2pqdA:
undetectable
5eevQ-2pqdA:
undetectable
5eevP-2pqdA:
10.20
5eevQ-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 5eevR-2pqdA:
undetectable
5eevS-2pqdA:
undetectable
5eevR-2pqdA:
10.20
5eevS-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 5eevS-2pqdA:
undetectable
5eevT-2pqdA:
undetectable
5eevS-2pqdA:
10.20
5eevT-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.36A 5eevT-2pqdA:
undetectable
5eevU-2pqdA:
undetectable
5eevT-2pqdA:
10.20
5eevU-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 5eevU-2pqdA:
undetectable
5eevV-2pqdA:
undetectable
5eevU-2pqdA:
10.20
5eevV-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.41A 5eewE-2pqdA:
undetectable
5eewF-2pqdA:
undetectable
5eewE-2pqdA:
10.20
5eewF-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.34A 5eewL-2pqdA:
0.0
5eewM-2pqdA:
0.0
5eewL-2pqdA:
10.20
5eewM-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.35A 5eewM-2pqdA:
0.0
5eewN-2pqdA:
0.0
5eewM-2pqdA:
10.20
5eewN-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.31A 5eewN-2pqdA:
undetectable
5eewO-2pqdA:
undetectable
5eewN-2pqdA:
10.20
5eewO-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.32A 5eewP-2pqdA:
undetectable
5eewQ-2pqdA:
undetectable
5eewP-2pqdA:
10.20
5eewQ-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 5eewR-2pqdA:
undetectable
5eewS-2pqdA:
undetectable
5eewR-2pqdA:
10.20
5eewS-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 5eewS-2pqdA:
undetectable
5eewT-2pqdA:
undetectable
5eewS-2pqdA:
10.20
5eewT-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.36A 5eewT-2pqdA:
undetectable
5eewU-2pqdA:
undetectable
5eewT-2pqdA:
10.20
5eewU-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 5eewU-2pqdA:
undetectable
5eewV-2pqdA:
undetectable
5eewU-2pqdA:
10.20
5eewV-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.41A 5eexE-2pqdA:
undetectable
5eexF-2pqdA:
undetectable
5eexE-2pqdA:
10.20
5eexF-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.34A 5eexL-2pqdA:
0.0
5eexM-2pqdA:
0.0
5eexL-2pqdA:
10.20
5eexM-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.35A 5eexM-2pqdA:
0.0
5eexN-2pqdA:
0.0
5eexM-2pqdA:
10.20
5eexN-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.31A 5eexN-2pqdA:
undetectable
5eexO-2pqdA:
undetectable
5eexN-2pqdA:
10.20
5eexO-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.32A 5eexP-2pqdA:
undetectable
5eexQ-2pqdA:
undetectable
5eexP-2pqdA:
10.20
5eexQ-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.31A 5eexQ-2pqdA:
undetectable
5eexR-2pqdA:
undetectable
5eexQ-2pqdA:
10.20
5eexR-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.32A 5eexR-2pqdA:
undetectable
5eexS-2pqdA:
undetectable
5eexR-2pqdA:
10.20
5eexS-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 5eexS-2pqdA:
undetectable
5eexT-2pqdA:
undetectable
5eexS-2pqdA:
10.20
5eexT-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.36A 5eexT-2pqdA:
undetectable
5eexU-2pqdA:
undetectable
5eexT-2pqdA:
10.20
5eexU-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 5eexU-2pqdA:
undetectable
5eexV-2pqdA:
undetectable
5eexU-2pqdA:
10.20
5eexV-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.41A 5eeyE-2pqdA:
undetectable
5eeyF-2pqdA:
undetectable
5eeyE-2pqdA:
10.20
5eeyF-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.34A 5eeyL-2pqdA:
0.0
5eeyM-2pqdA:
0.0
5eeyL-2pqdA:
10.20
5eeyM-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.34A 5eeyM-2pqdA:
0.0
5eeyN-2pqdA:
0.0
5eeyM-2pqdA:
10.20
5eeyN-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.31A 5eeyN-2pqdA:
undetectable
5eeyO-2pqdA:
undetectable
5eeyN-2pqdA:
10.20
5eeyO-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.32A 5eeyP-2pqdA:
undetectable
5eeyQ-2pqdA:
undetectable
5eeyP-2pqdA:
10.20
5eeyQ-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.31A 5eeyQ-2pqdA:
undetectable
5eeyR-2pqdA:
undetectable
5eeyQ-2pqdA:
10.20
5eeyR-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.32A 5eeyR-2pqdA:
undetectable
5eeyS-2pqdA:
undetectable
5eeyR-2pqdA:
10.20
5eeyS-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 5eeyS-2pqdA:
undetectable
5eeyT-2pqdA:
undetectable
5eeyS-2pqdA:
10.20
5eeyT-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.36A 5eeyT-2pqdA:
undetectable
5eeyU-2pqdA:
undetectable
5eeyT-2pqdA:
10.20
5eeyU-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 5eeyU-2pqdA:
undetectable
5eeyV-2pqdA:
undetectable
5eeyU-2pqdA:
10.20
5eeyV-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.41A 5eezE-2pqdA:
undetectable
5eezF-2pqdA:
undetectable
5eezE-2pqdA:
10.20
5eezF-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.44A 5eezJ-2pqdA:
undetectable
5eezK-2pqdA:
undetectable
5eezJ-2pqdA:
10.20
5eezK-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.34A 5eezL-2pqdA:
0.0
5eezM-2pqdA:
0.0
5eezL-2pqdA:
10.20
5eezM-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.34A 5eezM-2pqdA:
0.0
5eezN-2pqdA:
0.0
5eezM-2pqdA:
10.20
5eezN-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.31A 5eezN-2pqdA:
undetectable
5eezO-2pqdA:
undetectable
5eezN-2pqdA:
10.20
5eezO-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.32A 5eezP-2pqdA:
undetectable
5eezQ-2pqdA:
undetectable
5eezP-2pqdA:
10.20
5eezQ-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.31A 5eezQ-2pqdA:
undetectable
5eezR-2pqdA:
undetectable
5eezQ-2pqdA:
10.20
5eezR-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.32A 5eezR-2pqdA:
undetectable
5eezS-2pqdA:
undetectable
5eezR-2pqdA:
10.20
5eezS-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 5eezS-2pqdA:
undetectable
5eezT-2pqdA:
undetectable
5eezS-2pqdA:
10.20
5eezT-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.36A 5eezT-2pqdA:
undetectable
5eezU-2pqdA:
undetectable
5eezT-2pqdA:
10.20
5eezU-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 5eezU-2pqdA:
undetectable
5eezV-2pqdA:
undetectable
5eezU-2pqdA:
10.20
5eezV-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.41A 5ef0E-2pqdA:
undetectable
5ef0F-2pqdA:
undetectable
5ef0E-2pqdA:
10.20
5ef0F-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.34A 5ef0G-2pqdA:
undetectable
5ef0H-2pqdA:
undetectable
5ef0G-2pqdA:
10.20
5ef0H-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.44A 5ef0J-2pqdA:
undetectable
5ef0K-2pqdA:
undetectable
5ef0J-2pqdA:
10.20
5ef0K-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.34A 5ef0L-2pqdA:
0.0
5ef0M-2pqdA:
0.0
5ef0L-2pqdA:
10.20
5ef0M-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.34A 5ef0M-2pqdA:
0.0
5ef0N-2pqdA:
undetectable
5ef0M-2pqdA:
10.20
5ef0N-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.31A 5ef0N-2pqdA:
undetectable
5ef0O-2pqdA:
undetectable
5ef0N-2pqdA:
10.20
5ef0O-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.32A 5ef0P-2pqdA:
undetectable
5ef0Q-2pqdA:
undetectable
5ef0P-2pqdA:
10.20
5ef0Q-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.31A 5ef0Q-2pqdA:
undetectable
5ef0R-2pqdA:
undetectable
5ef0Q-2pqdA:
10.20
5ef0R-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.32A 5ef0R-2pqdA:
undetectable
5ef0S-2pqdA:
undetectable
5ef0R-2pqdA:
10.20
5ef0S-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 5ef0S-2pqdA:
undetectable
5ef0T-2pqdA:
undetectable
5ef0S-2pqdA:
10.20
5ef0T-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.36A 5ef0T-2pqdA:
undetectable
5ef0U-2pqdA:
undetectable
5ef0T-2pqdA:
10.20
5ef0U-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 5ef0U-2pqdA:
undetectable
5ef0V-2pqdA:
undetectable
5ef0U-2pqdA:
10.20
5ef0V-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.40A 5ef1E-2pqdA:
undetectable
5ef1F-2pqdA:
undetectable
5ef1E-2pqdA:
10.20
5ef1F-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.34A 5ef1G-2pqdA:
undetectable
5ef1H-2pqdA:
undetectable
5ef1G-2pqdA:
10.20
5ef1H-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.44A 5ef1J-2pqdA:
undetectable
5ef1K-2pqdA:
undetectable
5ef1J-2pqdA:
10.20
5ef1K-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.34A 5ef1L-2pqdA:
0.0
5ef1M-2pqdA:
0.0
5ef1L-2pqdA:
10.20
5ef1M-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.34A 5ef1M-2pqdA:
undetectable
5ef1N-2pqdA:
0.0
5ef1M-2pqdA:
10.20
5ef1N-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.31A 5ef1N-2pqdA:
undetectable
5ef1O-2pqdA:
undetectable
5ef1N-2pqdA:
10.20
5ef1O-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.32A 5ef1P-2pqdA:
undetectable
5ef1Q-2pqdA:
undetectable
5ef1P-2pqdA:
10.20
5ef1Q-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.31A 5ef1Q-2pqdA:
undetectable
5ef1R-2pqdA:
undetectable
5ef1Q-2pqdA:
10.20
5ef1R-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.32A 5ef1R-2pqdA:
undetectable
5ef1S-2pqdA:
undetectable
5ef1R-2pqdA:
10.20
5ef1S-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 5ef1S-2pqdA:
undetectable
5ef1T-2pqdA:
undetectable
5ef1S-2pqdA:
10.20
5ef1T-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.36A 5ef1T-2pqdA:
undetectable
5ef1U-2pqdA:
undetectable
5ef1T-2pqdA:
10.20
5ef1U-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 5ef1U-2pqdA:
undetectable
5ef1V-2pqdA:
undetectable
5ef1U-2pqdA:
10.20
5ef1V-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.40A 5ef2E-2pqdA:
undetectable
5ef2F-2pqdA:
undetectable
5ef2E-2pqdA:
10.20
5ef2F-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.34A 5ef2G-2pqdA:
undetectable
5ef2H-2pqdA:
undetectable
5ef2G-2pqdA:
10.20
5ef2H-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.42A 5ef2H-2pqdA:
undetectable
5ef2I-2pqdA:
undetectable
5ef2H-2pqdA:
10.20
5ef2I-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.44A 5ef2J-2pqdA:
undetectable
5ef2K-2pqdA:
undetectable
5ef2J-2pqdA:
10.20
5ef2K-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.34A 5ef2L-2pqdA:
0.0
5ef2M-2pqdA:
0.0
5ef2L-2pqdA:
10.20
5ef2M-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.34A 5ef2M-2pqdA:
0.0
5ef2N-2pqdA:
0.0
5ef2M-2pqdA:
10.20
5ef2N-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.31A 5ef2N-2pqdA:
undetectable
5ef2O-2pqdA:
undetectable
5ef2N-2pqdA:
10.20
5ef2O-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.32A 5ef2P-2pqdA:
undetectable
5ef2Q-2pqdA:
undetectable
5ef2P-2pqdA:
10.20
5ef2Q-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.30A 5ef2Q-2pqdA:
undetectable
5ef2R-2pqdA:
undetectable
5ef2Q-2pqdA:
10.20
5ef2R-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.32A 5ef2R-2pqdA:
undetectable
5ef2S-2pqdA:
undetectable
5ef2R-2pqdA:
10.20
5ef2S-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 5ef2S-2pqdA:
undetectable
5ef2T-2pqdA:
undetectable
5ef2S-2pqdA:
10.20
5ef2T-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.36A 5ef2T-2pqdA:
undetectable
5ef2U-2pqdA:
undetectable
5ef2T-2pqdA:
10.20
5ef2U-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.32A 5ef2U-2pqdA:
undetectable
5ef2V-2pqdA:
undetectable
5ef2U-2pqdA:
10.20
5ef2V-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.40A 5ef3E-2pqdA:
undetectable
5ef3F-2pqdA:
undetectable
5ef3E-2pqdA:
10.20
5ef3F-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.34A 5ef3G-2pqdA:
undetectable
5ef3H-2pqdA:
undetectable
5ef3G-2pqdA:
10.20
5ef3H-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 THR A 101
SER A 178
HIS A  32
THR A 203
HIS A 202
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
None
None
None
1.43A 5ef3J-2pqdA:
undetectable
5ef3K-2pqdA:
undetectable
5ef3J-2pqdA:
10.20
5ef3K-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.34A 5ef3L-2pqdA:
0.0
5ef3M-2pqdA:
0.0
5ef3L-2pqdA:
10.20
5ef3M-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.34A 5ef3M-2pqdA:
undetectable
5ef3N-2pqdA:
0.0
5ef3M-2pqdA:
10.20
5ef3N-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.31A 5ef3N-2pqdA:
undetectable
5ef3O-2pqdA:
undetectable
5ef3N-2pqdA:
10.20
5ef3O-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.32A 5ef3P-2pqdA:
undetectable
5ef3Q-2pqdA:
undetectable
5ef3P-2pqdA:
10.20
5ef3Q-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 9 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.30A 5ef3Q-2pqdA:
undetectable
5ef3R-2pqdA:
undetectable
5ef3Q-2pqdA:
10.20
5ef3R-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.32A 5ef3R-2pqdA:
undetectable
5ef3S-2pqdA:
undetectable
5ef3R-2pqdA:
10.20
5ef3S-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.33A 5ef3S-2pqdA:
undetectable
5ef3T-2pqdA:
undetectable
5ef3S-2pqdA:
10.20
5ef3T-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.36A 5ef3T-2pqdA:
undetectable
5ef3U-2pqdA:
undetectable
5ef3T-2pqdA:
10.20
5ef3U-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 HIS A  32
THR A 203
HIS A 202
THR A 101
SER A 178
None
None
None
GG9  A 501 (-3.3A)
GG9  A 501 ( 4.8A)
1.32A 5ef3U-2pqdA:
undetectable
5ef3V-2pqdA:
undetectable
5ef3U-2pqdA:
10.20
5ef3V-2pqdA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 GLY A 102
LEU A 207
GLY A 230
THR A 187
THR A 106
None
1.15A 5eskA-2pqdA:
undetectable
5eskA-2pqdA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
3 / 3 VAL A 290
LEU A 311
MET A 284
None
0.83A 5ikrA-2pqdA:
undetectable
5ikrA-2pqdA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.38A 5m5kB-2pqdA:
undetectable
5m5kB-2pqdA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.39A 5m5kC-2pqdA:
undetectable
5m5kC-2pqdA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.42A 5m66B-2pqdA:
undetectable
5m66B-2pqdA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
6 / 9 LEU A 185
GLY A 230
GLY A 189
LEU A 207
LEU A 214
ALA A 212
None
1.36A 5o96A-2pqdA:
undetectable
5o96B-2pqdA:
undetectable
5o96A-2pqdA:
19.91
5o96B-2pqdA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_C_SAMC501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 7 LEU A 185
GLY A 230
GLY A 189
LEU A 214
ALA A 212
None
1.27A 5o96C-2pqdA:
undetectable
5o96C-2pqdA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 8 VAL A 290
GLY A 276
GLN A 282
THR A 280
None
1.09A 5sxqB-2pqdA:
undetectable
5sxqB-2pqdA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 8 VAL A 290
GLY A 276
GLN A 282
THR A 280
None
1.10A 5syjA-2pqdA:
undetectable
5syjA-2pqdA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.38A 5v96A-2pqdA:
undetectable
5v96A-2pqdA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.35A 5v96B-2pqdA:
undetectable
5v96B-2pqdA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.37A 5v96C-2pqdA:
undetectable
5v96C-2pqdA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 LEU A 269
THR A 275
GLU A 299
LYS A 205
ASP A 201
None
1.49A 5v96D-2pqdA:
undetectable
5v96D-2pqdA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.37A 5v96D-2pqdA:
undetectable
5v96D-2pqdA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
3 / 3 ARG A 231
PHE A 210
LEU A 228
None
0.79A 5veuA-2pqdA:
undetectable
5veuA-2pqdA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 6 PHE A 119
ASP A 122
LEU A 125
GLY A 121
None
0.89A 5x5qE-2pqdA:
undetectable
5x5qE-2pqdA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 10 PHE A 119
ASP A 122
GLY A  97
PHE A  96
ASN A  58
None
1.47A 5x66D-2pqdA:
undetectable
5x66D-2pqdA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 8 PRO A 329
VAL A 333
LEU A 365
ILE A 406
None
0.87A 5y1yA-2pqdA:
undetectable
5y1yA-2pqdA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.33A 6aphA-2pqdA:
undetectable
6aphA-2pqdA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_2
(RIFAMPIN
MONOOXYGENASE)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 6 VAL A 421
LEU A 379
MET A 284
ARG A 382
None
1.33A 6brdB-2pqdA:
undetectable
6brdB-2pqdA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 LEU A  40
LEU A 182
GLY A 111
GLY A 108
LEU A  87
None
0.97A 6ecxA-2pqdA:
undetectable
6ecxA-2pqdA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_A_ADNA502_1
(-)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.36A 6f3mA-2pqdA:
undetectable
6f3mA-2pqdA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_B_ADNB502_1
(-)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.36A 6f3mB-2pqdA:
undetectable
6f3mB-2pqdA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_C_ADNC502_1
(-)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.36A 6f3mC-2pqdA:
undetectable
6f3mC-2pqdA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_1
(-)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.36A 6f3mD-2pqdA:
undetectable
6f3mD-2pqdA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_A_ADNA505_1
(-)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.38A 6f3nA-2pqdA:
undetectable
6f3nA-2pqdA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_B_ADNB505_1
(-)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.38A 6f3nB-2pqdA:
undetectable
6f3nB-2pqdA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_C_ADNC505_1
(-)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.38A 6f3nC-2pqdA:
undetectable
6f3nC-2pqdA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_D_ADND506_1
(-)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.38A 6f3nD-2pqdA:
undetectable
6f3nD-2pqdA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_1
(-)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.40A 6gbnA-2pqdA:
undetectable
6gbnA-2pqdA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_1
(-)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.39A 6gbnB-2pqdA:
undetectable
6gbnB-2pqdA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_1
(-)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.40A 6gbnC-2pqdA:
undetectable
6gbnC-2pqdA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_1
(-)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
5 / 12 THR A 275
ASP A 300
GLU A 299
LYS A 205
ASP A 201
None
1.39A 6gbnD-2pqdA:
undetectable
6gbnD-2pqdA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 6 GLY A 414
LEU A 415
VAL A 361
PHE A 250
None
0.83A 6h7lA-2pqdA:
undetectable
6h7lA-2pqdA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.)
4 / 6 GLY A 414
LEU A 415
VAL A 361
PHE A 250
None
0.84A 6h7lB-2pqdA:
undetectable
6h7lB-2pqdA:
12.47