SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pqv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_2
(HMG-COA REDUCTASE)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 8 GLU A  91
LEU A 133
ALA A 136
LEU A 137
 None
 0.78A 1hwiD-2pqvA:
undetectable		 1hwiD-2pqvA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		5 / 12 LEU A 120
LEU A 137
THR A  40
VAL A  31
ALA A  21
 None
 0.91A 1n5xA-2pqvA:
undetectable		 1n5xA-2pqvA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		5 / 12 LEU A 120
LEU A 137
THR A  40
VAL A  31
ALA A  21
 None
 0.91A 1n5xB-2pqvA:
undetectable		 1n5xB-2pqvA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 128
VAL A 131
VAL A  76
 None
 1.01A 1t85A-2pqvA:
undetectable		 1t85A-2pqvA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 128
VAL A 131
VAL A  76
 None
 0.99A 1t87A-2pqvA:
undetectable		 1t87A-2pqvA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 128
VAL A 131
VAL A  76
 None
 0.93A 1t87B-2pqvA:
undetectable		 1t87B-2pqvA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 128
VAL A 131
VAL A  76
 None
 0.98A 1yrcA-2pqvA:
undetectable		 1yrcA-2pqvA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 128
VAL A 131
VAL A  76
 None
 0.98A 1yrdA-2pqvA:
undetectable		 1yrdA-2pqvA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 6 THR A  40
LEU A 128
VAL A 131
VAL A  76
 None
 1.02A 2feuA-2pqvA:
undetectable		 2feuA-2pqvA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 128
VAL A 131
VAL A  76
 None
 1.01A 2feuB-2pqvA:
undetectable		 2feuB-2pqvA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 VAL A  75
PHE A  92
THR A  20
ARG A  18
 None
 1.21A 2kotA-2pqvA:
undetectable		 2kotA-2pqvA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 6 THR A  40
LEU A 128
VAL A 131
VAL A  76
 None
 0.97A 2zuiA-2pqvA:
undetectable		 2zuiA-2pqvA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 128
VAL A 131
VAL A  76
 None
 0.97A 2zwtA-2pqvA:
undetectable		 2zwtA-2pqvA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 128
VAL A 131
VAL A  76
 None
 0.98A 2zwuA-2pqvA:
undetectable		 2zwuA-2pqvA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 128
VAL A 131
VAL A  76
 None
 1.00A 3fwfA-2pqvA:
undetectable		 3fwfA-2pqvA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 128
VAL A 131
VAL A  76
 None
 1.01A 3fwfB-2pqvA:
undetectable		 3fwfB-2pqvA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 128
VAL A 131
VAL A  76
 None
 0.98A 3fwiA-2pqvA:
undetectable		 3fwiA-2pqvA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 128
VAL A 131
VAL A  76
 None
 1.00A 3fwjA-2pqvA:
undetectable		 3fwjA-2pqvA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 128
VAL A 131
VAL A  76
 None
 1.02A 3l63A-2pqvA:
undetectable		 3l63A-2pqvA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 128
VAL A 131
VAL A  76
 None
 1.00A 3wrhA-2pqvA:
undetectable		 3wrhA-2pqvA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 128
VAL A 131
VAL A  76
 None
 0.98A 3wrjA-2pqvA:
undetectable		 3wrjA-2pqvA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 128
VAL A 131
VAL A  76
 None
 1.00A 3wrlA-2pqvA:
undetectable		 3wrlA-2pqvA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 128
VAL A 131
VAL A  76
 None
 1.00A 3wrlE-2pqvA:
undetectable		 3wrlE-2pqvA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 128
VAL A 131
VAL A  76
 None
 1.01A 3wrmA-2pqvA:
undetectable		 3wrmA-2pqvA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 2pqv MUTT/NUDIX FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 128
VAL A 131
VAL A  76
 None
 0.97A 3wrmF-2pqvA:
undetectable		 3wrmF-2pqvA:
17.39