SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pr1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DRD_A_MIYA2001_1 (ACRB)	2pr1	UNCHARACTERIZED N-ACETYLTRANSFERASE YLBP (Bacillus subtilis)	5 / 9	GLY A 97 GLU A 102 ALA A 58 VAL A 57 PHE A 52	COA A 206 (-2.6A) None None None None	1.12A	2drdA-2pr1A: undetectable	2drdA-2pr1A: 10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DRD_A_MIYA2001_1 (ACRB)	2pr1	UNCHARACTERIZED N-ACETYLTRANSFERASE YLBP (Bacillus subtilis)	5 / 9	GLY A 97 ILE A 50 ALA A 58 VAL A 57 PHE A 52	COA A 206 (-2.6A) None None None None	1.13A	2drdA-2pr1A: undetectable	2drdA-2pr1A: 10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L1F_D_6ZPD902_1 (GLUTAMATE RECEPTOR 2)	2pr1	UNCHARACTERIZED N-ACETYLTRANSFERASE YLBP (Bacillus subtilis)	5 / 10	SER A 119 PHE A 122 PRO A 115 ASN A 114 LEU A 144	COA A 206 (-4.0A) COA A 206 (-3.9A) None None None	1.46A	5l1fD-2pr1A: undetectable	5l1fD-2pr1A: 13.48