SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pr7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VQ1_B_SAMB301_0 (N5-GLUTAMINE METHYLTRANSFERASE, HEMK)	2pr7	HALOACID DEHALOGENASE/EPOXIDE HYDROLASE FAMILY (Corynebacterium glutamicum)	5 / 12	GLY A 35 GLY A 3 VAL A 37 GLU A 55 ALA A 83	None	1.02A	1vq1B-2pr7A: undetectable	1vq1B-2pr7A: 22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_C_DVAC59_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	2pr7	HALOACID DEHALOGENASE/EPOXIDE HYDROLASE FAMILY (Corynebacterium glutamicum)	3 / 3	GLY A 3 GLY A 33 GLY A 35	None	0.30A	3bogC-2pr7A: undetectable	3bogC-2pr7A: 19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MGH_A_ACTA1320_0 (PHOSPHORIBOSYLFORMYL GLYCINAMIDINE SYNTHASE)	2pr7	HALOACID DEHALOGENASE/EPOXIDE HYDROLASE FAMILY (Corynebacterium glutamicum)	5 / 5	VAL A 63 LEU A 65 ILE A 51 LEU A 54 ARG A 52	None None None EDO A 138 ( 4.8A) None	1.31A	4mghA-2pr7A: undetectable	4mghA-2pr7A: 8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X1Y_B_LOCB502_1 (TUBULIN BETA CHAIN)	2pr7	HALOACID DEHALOGENASE/EPOXIDE HYDROLASE FAMILY (Corynebacterium glutamicum)	5 / 12	LEU A 26 LEU A 132 ALA A 29 LEU A 4 VAL A 123	None	1.11A	4x1yB-2pr7A: undetectable	4x1yB-2pr7A: 15.67

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1VQ1_B_SAMB301_0","N5-GLUTAMINE METHYLTRANSFERASE, HEMK","2pr7","HALOACID DEHALOGENASE\/EPOXIDE HYDROLASE FAMILY","Corynebacterium glutamicum",5,"GLY A  35;GLY A   3;VAL A  37;GLU A  55;ALA A  83","None","1.02A","1vq1B-2pr7A:undetectable","1vq1B-2pr7A:22.95"],["3BOG_C_DVAC59_0","6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN","2pr7","HALOACID DEHALOGENASE\/EPOXIDE HYDROLASE FAMILY","Corynebacterium glutamicum",3,"GLY A   3;GLY A  33;GLY A  35","None","0.30A","3bogC-2pr7A:undetectable","3bogC-2pr7A:19.57"],["4MGH_A_ACTA1320_0","PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE","2pr7","HALOACID DEHALOGENASE\/EPOXIDE HYDROLASE FAMILY","Corynebacterium glutamicum",5,"VAL A  63;LEU A  65;ILE A  51;LEU A  54;ARG A  52","None;None;None;EDO A 138 ( 4.8A);None","1.31A","4mghA-2pr7A:undetectable","4mghA-2pr7A:8.19"],["4X1Y_B_LOCB502_1","TUBULIN BETA CHAIN","2pr7","HALOACID DEHALOGENASE\/EPOXIDE HYDROLASE FAMILY","Corynebacterium glutamicum",5,"LEU A  26;LEU A 132;ALA A  29;LEU A   4;VAL A 123","None","1.11A","4x1yB-2pr7A:undetectable","4x1yB-2pr7A:15.67"]]