SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2prr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5R_A_RBFA859_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2prr ALKYLHYDROPEROXIDASE
AHPD CORE:
UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Cupriavidus
pinatubonensis) 		5 / 11 LEU A  68
GLU A  72
ALA A  79
ARG A 122
PHE A 153
 None
 1.43A 1l5rA-2prrA:
undetectable		 1l5rA-2prrA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 2prr ALKYLHYDROPEROXIDASE
AHPD CORE:
UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 6 ASP A 160
ILE A 161
LEU A 148
GLU A  72
 None
 0.98A 2ya7A-2prrA:
undetectable		 2ya7A-2prrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 2prr ALKYLHYDROPEROXIDASE
AHPD CORE:
UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 6 ASP A 160
ILE A 161
LEU A 148
GLU A  72
 None
 1.00A 2ya7B-2prrA:
undetectable		 2ya7B-2prrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 2prr ALKYLHYDROPEROXIDASE
AHPD CORE:
UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 6 ASP A 160
ILE A 161
LEU A 148
GLU A  72
 None
 0.99A 2ya7D-2prrA:
undetectable		 2ya7D-2prrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 2prr ALKYLHYDROPEROXIDASE
AHPD CORE:
UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Cupriavidus
pinatubonensis) 		5 / 12 LEU A  42
ILE A  27
PHE A  55
PHE A  54
SER A 171
 None
None
None
None
PEG  A 199 (-2.9A)
 1.02A 3ko0G-2prrA:
1.6
3ko0H-2prrA:
1.8
3ko0I-2prrA:
1.8
3ko0J-2prrA:
1.8		 3ko0G-2prrA:
20.90
3ko0H-2prrA:
20.90
3ko0I-2prrA:
20.90
3ko0J-2prrA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 2prr ALKYLHYDROPEROXIDASE
AHPD CORE:
UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Cupriavidus
pinatubonensis) 		5 / 9 VAL A 140
ILE A 161
ALA A 162
THR A 165
THR A  80
 None
 1.20A 3mdtA-2prrA:
undetectable		 3mdtA-2prrA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 2prr ALKYLHYDROPEROXIDASE
AHPD CORE:
UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 5 PHE A 129
ALA A 130
THR A 165
LEU A  68
 None
 1.11A 3t3zC-2prrA:
undetectable		 3t3zC-2prrA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 2prr ALKYLHYDROPEROXIDASE
AHPD CORE:
UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 7 PHE A 129
ALA A 130
THR A 165
LEU A  68
 None
 0.97A 4ejgA-2prrA:
undetectable		 4ejgA-2prrA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 2prr ALKYLHYDROPEROXIDASE
AHPD CORE:
UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Cupriavidus
pinatubonensis) 		3 / 3 GLU A 185
ILE A   8
ALA A  92
 None
 0.61A 4wnwB-2prrA:
undetectable		 4wnwB-2prrA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 2prr ALKYLHYDROPEROXIDASE
AHPD CORE:
UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 4 VAL A  13
ILE A  27
ASN A 183
VAL A  40
 None
None
None
PEG  A 199 (-4.5A)
 1.32A 5ajqA-2prrA:
undetectable		 5ajqA-2prrA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H4D_A_BBIA403_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 2prr ALKYLHYDROPEROXIDASE
AHPD CORE:
UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 6 PHE A  55
PHE A 167
GLU A  74
VAL A  77
 None
 1.27A 5h4dA-2prrA:
undetectable		 5h4dA-2prrA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 2prr ALKYLHYDROPEROXIDASE
AHPD CORE:
UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Cupriavidus
pinatubonensis) 		5 / 7 VAL A 110
LEU A  97
ALA A 111
LEU A 127
LEU A 131
 None
 1.09A 5jq7A-2prrA:
undetectable		 5jq7A-2prrA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2prr ALKYLHYDROPEROXIDASE
AHPD CORE:
UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Cupriavidus
pinatubonensis) 		5 / 12 ILE A  96
PHE A 168
TYR A  88
ALA A  92
VAL A  78
 None
None
PEG  A 199 (-4.7A)
None
None
 1.19A 5n0rA-2prrA:
undetectable		 5n0rA-2prrA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2prr ALKYLHYDROPEROXIDASE
AHPD CORE:
UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Cupriavidus
pinatubonensis) 		5 / 12 ILE A  96
PHE A 168
TYR A  88
ALA A  92
VAL A  78
 None
None
PEG  A 199 (-4.7A)
None
None
 1.18A 5n0xB-2prrA:
undetectable		 5n0xB-2prrA:
20.54