SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2prv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VQY_A_PARA1201_1 (AAC(6')-IB)	2prv	UNCHARACTERIZED PROTEIN YOBK (Bacillus subtilis)	5 / 12	GLY A 53 TYR A 43 LEU A 100 VAL A 112 TYR A 98	None	1.50A	2vqyA-2prvA: undetectable	2vqyA-2prvA: 23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FPJ_B_SAMB301_0 (PUTATIVE UNCHARACTERIZED PROTEIN)	2prv	UNCHARACTERIZED PROTEIN YOBK (Bacillus subtilis)	5 / 12	PHE A 56 ILE A 137 VAL A 58 ILE A 18 VAL A 6	None None EDO A 157 (-4.2A) None None	1.18A	3fpjB-2prvA: undetectable	3fpjB-2prvA: 21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E0F_A_RBFA301_2 (RIBOFLAVIN SYNTHASE SUBUNIT ALPHA)	2prv	UNCHARACTERIZED PROTEIN YOBK (Bacillus subtilis)	3 / 3	LYS A 78 THR A 74 ILE A 31	EDO A 159 (-3.4A) None None	0.82A	4e0fB-2prvA: undetectable	4e0fB-2prvA: 19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EJW_A_SRYA2001_2 (TRANSCRIPTIONAL REGULATOR TCAR)	2prv	UNCHARACTERIZED PROTEIN YOBK (Bacillus subtilis)	4 / 6	GLU A 131 ILE A 130 GLU A 32 VAL A 88	None None EDO A 161 (-3.2A) None	0.92A	4ejwB-2prvA: undetectable	4ejwB-2prvA: 23.30

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2VQY_A_PARA1201_1","AAC(6')-IB","2prv","UNCHARACTERIZED PROTEIN YOBK","Bacillus subtilis",5,"GLY A  53;TYR A  43;LEU A 100;VAL A 112;TYR A  98","None","1.50A","2vqyA-2prvA:undetectable","2vqyA-2prvA:23.72"],["3FPJ_B_SAMB301_0","PUTATIVE UNCHARACTERIZED PROTEIN","2prv","UNCHARACTERIZED PROTEIN YOBK","Bacillus subtilis",5,"PHE A  56;ILE A 137;VAL A  58;ILE A  18;VAL A   6","None;None;EDO A 157 (-4.2A);None;None","1.18A","3fpjB-2prvA:undetectable","3fpjB-2prvA:21.48"],["4E0F_A_RBFA301_2","RIBOFLAVIN SYNTHASE SUBUNIT ALPHA;RIBOFLAVIN SYNTHASE SUBUNIT ALPHA","2prv","UNCHARACTERIZED PROTEIN YOBK","Bacillus subtilis",3,"LYS A  78;THR A  74;ILE A  31","EDO A 159 (-3.4A);None;None","0.82A","4e0fB-2prvA:undetectable","4e0fB-2prvA:19.81"],["4EJW_A_SRYA2001_2","TRANSCRIPTIONAL REGULATOR TCAR;TRANSCRIPTIONAL REGULATOR TCAR","2prv","UNCHARACTERIZED PROTEIN YOBK","Bacillus subtilis",4,"GLU A 131;ILE A 130;GLU A  32;VAL A  88","None;None;EDO A 161 (-3.2A);None","0.92A","4ejwB-2prvA:undetectable","4ejwB-2prvA:23.30"]]