SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2prx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 9 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.32A 1c9sL-2prxA:
undetectable
1c9sM-2prxA:
undetectable
1c9sL-2prxA:
18.54
1c9sM-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 9 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.31A 1c9sM-2prxA:
undetectable
1c9sN-2prxA:
undetectable
1c9sM-2prxA:
18.54
1c9sN-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 9 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.34A 1c9sS-2prxA:
undetectable
1c9sT-2prxA:
undetectable
1c9sS-2prxA:
18.54
1c9sT-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 9 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.27A 1gtfA-2prxA:
undetectable
1gtfB-2prxA:
undetectable
1gtfA-2prxA:
18.54
1gtfB-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 9 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.33A 1gtfO-2prxA:
undetectable
1gtfP-2prxA:
undetectable
1gtfO-2prxA:
18.54
1gtfP-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.35A 1gtfP-2prxA:
undetectable
1gtfQ-2prxA:
undetectable
1gtfP-2prxA:
18.54
1gtfQ-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.33A 1gtfT-2prxA:
undetectable
1gtfU-2prxA:
undetectable
1gtfT-2prxA:
18.54
1gtfU-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 11 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.34A 1gtfU-2prxA:
undetectable
1gtfV-2prxA:
undetectable
1gtfU-2prxA:
18.54
1gtfV-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.33A 1gtfL-2prxA:
undetectable
1gtfV-2prxA:
undetectable
1gtfL-2prxA:
18.54
1gtfV-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 9 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.31A 1gtnG-2prxA:
undetectable
1gtnH-2prxA:
undetectable
1gtnG-2prxA:
18.54
1gtnH-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 9 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.35A 1gtnL-2prxA:
undetectable
1gtnM-2prxA:
undetectable
1gtnL-2prxA:
18.54
1gtnM-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.35A 1gtnN-2prxA:
undetectable
1gtnO-2prxA:
undetectable
1gtnN-2prxA:
18.54
1gtnO-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 9 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.39A 1gtnS-2prxA:
undetectable
1gtnT-2prxA:
undetectable
1gtnS-2prxA:
18.54
1gtnT-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 11 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.36A 1utdM-2prxA:
undetectable
1utdN-2prxA:
undetectable
1utdM-2prxA:
18.54
1utdN-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.33A 1utdN-2prxA:
undetectable
1utdO-2prxA:
undetectable
1utdN-2prxA:
18.54
1utdO-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.37A 1utdR-2prxA:
undetectable
1utdS-2prxA:
undetectable
1utdR-2prxA:
18.54
1utdS-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
4 / 8 SER A  72
ILE A  65
VAL A 129
GLY A 143
None
0.68A 3dcjB-2prxA:
undetectable
3dcjB-2prxA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
3 / 3 VAL A 122
LYS A 126
HIS A  68
None
0.86A 3elzA-2prxA:
1.9
3elzA-2prxA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 VAL A 129
GLY A  71
ALA A  73
ALA A  75
TRP A  34
None
1.18A 3ucjA-2prxA:
undetectable
3ucjA-2prxA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 VAL A 129
GLY A  71
ALA A  73
ALA A  75
TRP A  34
None
1.15A 3ucjB-2prxA:
undetectable
3ucjB-2prxA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 9 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.30A 5eeuC-2prxA:
undetectable
5eeuD-2prxA:
undetectable
5eeuC-2prxA:
18.54
5eeuD-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.29A 5eeuG-2prxA:
undetectable
5eeuH-2prxA:
undetectable
5eeuG-2prxA:
18.54
5eeuH-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.38A 5eeuN-2prxA:
undetectable
5eeuO-2prxA:
undetectable
5eeuN-2prxA:
18.54
5eeuO-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.33A 5eeuP-2prxA:
undetectable
5eeuQ-2prxA:
undetectable
5eeuP-2prxA:
18.54
5eeuQ-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.34A 5eeuR-2prxA:
undetectable
5eeuS-2prxA:
undetectable
5eeuR-2prxA:
18.54
5eeuS-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.37A 5eeuS-2prxA:
undetectable
5eeuT-2prxA:
undetectable
5eeuS-2prxA:
18.54
5eeuT-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.32A 5eeuT-2prxA:
undetectable
5eeuU-2prxA:
undetectable
5eeuT-2prxA:
18.54
5eeuU-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.34A 5eeuU-2prxA:
undetectable
5eeuV-2prxA:
undetectable
5eeuU-2prxA:
18.54
5eeuV-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 9 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.30A 5eevC-2prxA:
undetectable
5eevD-2prxA:
undetectable
5eevC-2prxA:
18.54
5eevD-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.29A 5eevG-2prxA:
undetectable
5eevH-2prxA:
undetectable
5eevG-2prxA:
18.54
5eevH-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.38A 5eevN-2prxA:
undetectable
5eevO-2prxA:
undetectable
5eevN-2prxA:
18.54
5eevO-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.33A 5eevP-2prxA:
undetectable
5eevQ-2prxA:
undetectable
5eevP-2prxA:
18.54
5eevQ-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.35A 5eevR-2prxA:
undetectable
5eevS-2prxA:
undetectable
5eevR-2prxA:
18.54
5eevS-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.37A 5eevS-2prxA:
undetectable
5eevT-2prxA:
undetectable
5eevS-2prxA:
18.54
5eevT-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.33A 5eevT-2prxA:
undetectable
5eevU-2prxA:
undetectable
5eevT-2prxA:
18.54
5eevU-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.33A 5eevU-2prxA:
undetectable
5eevV-2prxA:
undetectable
5eevU-2prxA:
18.54
5eevV-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 9 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.30A 5eewC-2prxA:
undetectable
5eewD-2prxA:
undetectable
5eewC-2prxA:
18.54
5eewD-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.29A 5eewG-2prxA:
undetectable
5eewH-2prxA:
undetectable
5eewG-2prxA:
18.54
5eewH-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.38A 5eewN-2prxA:
undetectable
5eewO-2prxA:
undetectable
5eewN-2prxA:
18.54
5eewO-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.33A 5eewP-2prxA:
undetectable
5eewQ-2prxA:
undetectable
5eewP-2prxA:
18.54
5eewQ-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.34A 5eewR-2prxA:
undetectable
5eewS-2prxA:
undetectable
5eewR-2prxA:
18.54
5eewS-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.37A 5eewS-2prxA:
undetectable
5eewT-2prxA:
undetectable
5eewS-2prxA:
18.54
5eewT-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.32A 5eewT-2prxA:
undetectable
5eewU-2prxA:
undetectable
5eewT-2prxA:
18.54
5eewU-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.33A 5eewU-2prxA:
undetectable
5eewV-2prxA:
undetectable
5eewU-2prxA:
18.54
5eewV-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 9 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.30A 5eexC-2prxA:
undetectable
5eexD-2prxA:
undetectable
5eexC-2prxA:
18.54
5eexD-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.29A 5eexG-2prxA:
undetectable
5eexH-2prxA:
undetectable
5eexG-2prxA:
18.54
5eexH-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 11 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.27A 5eexI-2prxA:
undetectable
5eexJ-2prxA:
undetectable
5eexI-2prxA:
18.54
5eexJ-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.30A 5eexA-2prxA:
undetectable
5eexK-2prxA:
undetectable
5eexA-2prxA:
18.54
5eexK-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.38A 5eexN-2prxA:
undetectable
5eexO-2prxA:
undetectable
5eexN-2prxA:
18.54
5eexO-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.33A 5eexP-2prxA:
undetectable
5eexQ-2prxA:
undetectable
5eexP-2prxA:
18.54
5eexQ-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.35A 5eexR-2prxA:
undetectable
5eexS-2prxA:
undetectable
5eexR-2prxA:
18.54
5eexS-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.37A 5eexS-2prxA:
undetectable
5eexT-2prxA:
undetectable
5eexS-2prxA:
18.54
5eexT-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.32A 5eexT-2prxA:
undetectable
5eexU-2prxA:
undetectable
5eexT-2prxA:
18.54
5eexU-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.33A 5eexU-2prxA:
undetectable
5eexV-2prxA:
undetectable
5eexU-2prxA:
18.54
5eexV-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 9 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.30A 5eeyC-2prxA:
undetectable
5eeyD-2prxA:
undetectable
5eeyC-2prxA:
18.54
5eeyD-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.29A 5eeyG-2prxA:
undetectable
5eeyH-2prxA:
undetectable
5eeyG-2prxA:
18.54
5eeyH-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 11 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.27A 5eeyI-2prxA:
undetectable
5eeyJ-2prxA:
undetectable
5eeyI-2prxA:
18.54
5eeyJ-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.38A 5eeyN-2prxA:
undetectable
5eeyO-2prxA:
undetectable
5eeyN-2prxA:
18.54
5eeyO-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.33A 5eeyP-2prxA:
undetectable
5eeyQ-2prxA:
undetectable
5eeyP-2prxA:
18.54
5eeyQ-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.34A 5eeyR-2prxA:
undetectable
5eeyS-2prxA:
undetectable
5eeyR-2prxA:
18.54
5eeyS-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.37A 5eeyS-2prxA:
undetectable
5eeyT-2prxA:
undetectable
5eeyS-2prxA:
18.54
5eeyT-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.32A 5eeyT-2prxA:
undetectable
5eeyU-2prxA:
undetectable
5eeyT-2prxA:
18.54
5eeyU-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.34A 5eeyU-2prxA:
undetectable
5eeyV-2prxA:
undetectable
5eeyU-2prxA:
18.54
5eeyV-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 9 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.30A 5eezC-2prxA:
undetectable
5eezD-2prxA:
undetectable
5eezC-2prxA:
18.54
5eezD-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.29A 5eezG-2prxA:
undetectable
5eezH-2prxA:
undetectable
5eezG-2prxA:
18.54
5eezH-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 11 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.27A 5eezI-2prxA:
undetectable
5eezJ-2prxA:
undetectable
5eezI-2prxA:
18.54
5eezJ-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.38A 5eezN-2prxA:
undetectable
5eezO-2prxA:
undetectable
5eezN-2prxA:
18.54
5eezO-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.33A 5eezP-2prxA:
undetectable
5eezQ-2prxA:
undetectable
5eezP-2prxA:
18.54
5eezQ-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.34A 5eezR-2prxA:
undetectable
5eezS-2prxA:
undetectable
5eezR-2prxA:
18.54
5eezS-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.37A 5eezS-2prxA:
undetectable
5eezT-2prxA:
undetectable
5eezS-2prxA:
18.54
5eezT-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.32A 5eezT-2prxA:
undetectable
5eezU-2prxA:
undetectable
5eezT-2prxA:
18.54
5eezU-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.33A 5eezU-2prxA:
undetectable
5eezV-2prxA:
undetectable
5eezU-2prxA:
18.54
5eezV-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 9 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.30A 5ef0C-2prxA:
undetectable
5ef0D-2prxA:
undetectable
5ef0C-2prxA:
18.54
5ef0D-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.29A 5ef0G-2prxA:
undetectable
5ef0H-2prxA:
undetectable
5ef0G-2prxA:
18.54
5ef0H-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 11 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.27A 5ef0I-2prxA:
undetectable
5ef0J-2prxA:
undetectable
5ef0I-2prxA:
18.54
5ef0J-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.30A 5ef0A-2prxA:
undetectable
5ef0K-2prxA:
undetectable
5ef0A-2prxA:
18.54
5ef0K-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.38A 5ef0N-2prxA:
undetectable
5ef0O-2prxA:
undetectable
5ef0N-2prxA:
18.54
5ef0O-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.33A 5ef0P-2prxA:
undetectable
5ef0Q-2prxA:
undetectable
5ef0P-2prxA:
18.54
5ef0Q-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.34A 5ef0R-2prxA:
undetectable
5ef0S-2prxA:
undetectable
5ef0R-2prxA:
18.54
5ef0S-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.37A 5ef0S-2prxA:
undetectable
5ef0T-2prxA:
undetectable
5ef0S-2prxA:
18.54
5ef0T-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.32A 5ef0T-2prxA:
undetectable
5ef0U-2prxA:
undetectable
5ef0T-2prxA:
18.54
5ef0U-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.34A 5ef0U-2prxA:
undetectable
5ef0V-2prxA:
undetectable
5ef0U-2prxA:
18.54
5ef0V-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 9 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.30A 5ef1C-2prxA:
undetectable
5ef1D-2prxA:
undetectable
5ef1C-2prxA:
18.54
5ef1D-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.29A 5ef1G-2prxA:
undetectable
5ef1H-2prxA:
undetectable
5ef1G-2prxA:
18.54
5ef1H-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 11 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.27A 5ef1I-2prxA:
undetectable
5ef1J-2prxA:
undetectable
5ef1I-2prxA:
18.54
5ef1J-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.38A 5ef1N-2prxA:
undetectable
5ef1O-2prxA:
undetectable
5ef1N-2prxA:
18.54
5ef1O-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.33A 5ef1P-2prxA:
undetectable
5ef1Q-2prxA:
undetectable
5ef1P-2prxA:
18.54
5ef1Q-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.34A 5ef1R-2prxA:
undetectable
5ef1S-2prxA:
undetectable
5ef1R-2prxA:
18.54
5ef1S-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.37A 5ef1S-2prxA:
undetectable
5ef1T-2prxA:
undetectable
5ef1S-2prxA:
18.54
5ef1T-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.32A 5ef1T-2prxA:
undetectable
5ef1U-2prxA:
undetectable
5ef1T-2prxA:
18.54
5ef1U-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.33A 5ef1U-2prxA:
undetectable
5ef1V-2prxA:
undetectable
5ef1U-2prxA:
18.54
5ef1V-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 9 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.30A 5ef2C-2prxA:
undetectable
5ef2D-2prxA:
undetectable
5ef2C-2prxA:
18.54
5ef2D-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.29A 5ef2G-2prxA:
undetectable
5ef2H-2prxA:
undetectable
5ef2G-2prxA:
18.54
5ef2H-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 11 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.27A 5ef2I-2prxA:
undetectable
5ef2J-2prxA:
undetectable
5ef2I-2prxA:
18.54
5ef2J-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.38A 5ef2N-2prxA:
undetectable
5ef2O-2prxA:
undetectable
5ef2N-2prxA:
18.54
5ef2O-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.33A 5ef2P-2prxA:
undetectable
5ef2Q-2prxA:
undetectable
5ef2P-2prxA:
18.54
5ef2Q-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.34A 5ef2R-2prxA:
undetectable
5ef2S-2prxA:
undetectable
5ef2R-2prxA:
18.54
5ef2S-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.37A 5ef2S-2prxA:
undetectable
5ef2T-2prxA:
undetectable
5ef2S-2prxA:
18.54
5ef2T-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.33A 5ef2T-2prxA:
undetectable
5ef2U-2prxA:
undetectable
5ef2T-2prxA:
18.54
5ef2U-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.33A 5ef2U-2prxA:
undetectable
5ef2V-2prxA:
undetectable
5ef2U-2prxA:
18.54
5ef2V-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 9 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.30A 5ef3C-2prxA:
undetectable
5ef3D-2prxA:
undetectable
5ef3C-2prxA:
18.54
5ef3D-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.29A 5ef3G-2prxA:
undetectable
5ef3H-2prxA:
undetectable
5ef3G-2prxA:
18.54
5ef3H-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 11 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.27A 5ef3I-2prxA:
undetectable
5ef3J-2prxA:
undetectable
5ef3I-2prxA:
18.54
5ef3J-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.30A 5ef3A-2prxA:
undetectable
5ef3K-2prxA:
undetectable
5ef3A-2prxA:
18.54
5ef3K-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.38A 5ef3N-2prxA:
undetectable
5ef3O-2prxA:
undetectable
5ef3N-2prxA:
18.54
5ef3O-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.33A 5ef3P-2prxA:
undetectable
5ef3Q-2prxA:
undetectable
5ef3P-2prxA:
18.54
5ef3Q-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.35A 5ef3R-2prxA:
undetectable
5ef3S-2prxA:
undetectable
5ef3R-2prxA:
18.54
5ef3S-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.37A 5ef3S-2prxA:
undetectable
5ef3T-2prxA:
undetectable
5ef3S-2prxA:
18.54
5ef3T-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.32A 5ef3T-2prxA:
undetectable
5ef3U-2prxA:
undetectable
5ef3T-2prxA:
18.54
5ef3U-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
5 / 10 GLY A 117
HIS A  68
ALA A  76
THR A  39
ILE A 119
None
1.34A 5ef3U-2prxA:
undetectable
5ef3V-2prxA:
undetectable
5ef3U-2prxA:
18.54
5ef3V-2prxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
4 / 7 VAL A 127
ALA A 147
GLY A  69
VAL A 129
None
0.90A 5fpdA-2prxA:
undetectable
5fpdA-2prxA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
4 / 7 VAL A 127
ALA A 147
GLY A  69
VAL A 129
None
0.91A 5fpdB-2prxA:
undetectable
5fpdB-2prxA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica)
4 / 5 LEU A  30
CYH A  67
THR A  70
GLY A  71
None
1.28A 6gtqA-2prxA:
undetectable
6gtqA-2prxA:
21.61