SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2psb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 2psb YERB PROTEIN
(Bacillus
subtilis) 		3 / 3 ILE A  56
ILE A 297
THR A 293
 None
 0.60A 1rg7A-2psbA:
undetectable		 1rg7A-2psbA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_1
(VITAMIN D3 RECEPTOR)		 2psb YERB PROTEIN
(Bacillus
subtilis) 		4 / 5 TYR A 199
SER A 212
HIS A 141
HIS A  40
 None
 1.26A 1s19A-2psbA:
undetectable		 1s19A-2psbA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 2psb YERB PROTEIN
(Bacillus
subtilis) 		4 / 7 PHE A 260
TYR A 199
ASN A 200
VAL A 186
 None
 1.30A 1wu8A-2psbA:
undetectable
1wu8C-2psbA:
undetectable		 1wu8A-2psbA:
20.12
1wu8C-2psbA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 2psb YERB PROTEIN
(Bacillus
subtilis) 		5 / 12 VAL A 280
LEU A 286
THR A 293
GLY A 257
LEU A  92
 None
 1.18A 2cbrA-2psbA:
undetectable		 2cbrA-2psbA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 2psb YERB PROTEIN
(Bacillus
subtilis) 		4 / 8 SER A  93
PHE A  96
ASN A  94
ASP A  97
 None
 1.19A 3n66B-2psbA:
undetectable		 3n66B-2psbA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_A_SAMA601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 2psb YERB PROTEIN
(Bacillus
subtilis) 		5 / 12 GLN A  74
ILE A 150
VAL A  79
VAL A  35
VAL A 101
 None
 1.16A 5dpdA-2psbA:
undetectable		 5dpdA-2psbA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 2psb YERB PROTEIN
(Bacillus
subtilis) 		5 / 12 VAL A 278
PRO A 279
THR A 165
ILE A  54
PHE A  96
 None
 1.41A 5hgcA-2psbA:
undetectable		 5hgcA-2psbA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2psb YERB PROTEIN
(Bacillus
subtilis) 		4 / 8 SER A  93
PHE A  96
ASN A  94
ASP A  97
 None
 1.19A 5vunA-2psbA:
undetectable		 5vunA-2psbA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2psb YERB PROTEIN
(Bacillus
subtilis) 		4 / 8 SER A  93
PHE A  96
ASN A  94
ASP A  97
 None
 1.18A 5vunB-2psbA:
undetectable		 5vunB-2psbA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2psb YERB PROTEIN
(Bacillus
subtilis) 		4 / 8 SER A  93
PHE A  96
ASN A  94
ASP A  97
 None
 1.20A 5vuoB-2psbA:
undetectable		 5vuoB-2psbA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA502_1
(CYTOCHROME P450 2C9)		 2psb YERB PROTEIN
(Bacillus
subtilis) 		5 / 12 ALA A  69
PHE A  89
LEU A  49
VAL A  79
VAL A  82
 None
 1.19A 5x24A-2psbA:
undetectable		 5x24A-2psbA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_1
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 2psb YERB PROTEIN
(Bacillus
subtilis) 		4 / 6 SER A 115
GLU A  87
ARG A 246
ASP A 242
 None
 1.10A 5zw4A-2psbA:
undetectable		 5zw4A-2psbA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2psb YERB PROTEIN
(Bacillus
subtilis) 		4 / 8 SER A  93
PHE A  96
ASN A  94
ASP A  97
 None
 1.17A 6auuB-2psbA:
undetectable		 6auuB-2psbA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IEY_A_CLMA401_0
(ESTERASE)		 2psb YERB PROTEIN
(Bacillus
subtilis) 		5 / 11 ILE A 295
ALA A 236
LEU A 251
GLY A 254
PHE A 232
 None
 1.26A 6ieyA-2psbA:
undetectable
6ieyB-2psbA:
undetectable		 6ieyA-2psbA:
23.41
6ieyB-2psbA:
23.41