SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2psf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		3 / 3 ALA A 123
VAL A 117
TRP A  60
 None
 0.82A 1av2C-2psfA:
undetectable
1av2D-2psfA:
undetectable		 1av2C-2psfA:
4.62
1av2D-2psfA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		3 / 3 SER A 168
GLU A 169
GLU A 170
 None
 0.57A 1eqbD-2psfA:
undetectable		 1eqbD-2psfA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		3 / 3 SER A 168
GLU A 169
GLU A 170
 None
 0.58A 1eqbB-2psfA:
undetectable		 1eqbB-2psfA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		4 / 7 PHE A 181
SER A 188
ALA A  54
PHE A 286
 None
 1.18A 1fxvA-2psfA:
undetectable
1fxvB-2psfA:
undetectable		 1fxvA-2psfA:
22.33
1fxvB-2psfA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		5 / 9 ILE A  15
GLY A  17
TYR A 202
GLU A 289
ARG A 192
 None
 1.25A 1mrgA-2psfA:
undetectable		 1mrgA-2psfA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		3 / 3 ALA A 123
VAL A 117
TRP A  60
 None
 0.91A 1nrmA-2psfA:
undetectable		 1nrmA-2psfA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		3 / 3 ALA A 123
VAL A 117
TRP A  60
 None
 0.91A 1nrmB-2psfA:
undetectable		 1nrmB-2psfA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		3 / 3 ALA A 123
VAL A 117
TRP A  60
 None
 0.89A 1nt5A-2psfA:
undetectable		 1nt5A-2psfA:
3.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		3 / 3 ALA A 123
VAL A 117
TRP A  60
 None
 0.89A 1nt5B-2psfA:
undetectable		 1nt5B-2psfA:
3.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		3 / 3 ALA A 123
VAL A 117
TRP A  60
 None
 0.89A 1nt6A-2psfA:
undetectable		 1nt6A-2psfA:
3.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		3 / 3 ALA A 123
VAL A 117
TRP A  60
 None
 0.89A 1nt6B-2psfA:
undetectable		 1nt6B-2psfA:
3.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		3 / 3 ALA A 123
VAL A 117
TRP A  60
 None
 0.85A 1w5uC-2psfA:
undetectable
1w5uD-2psfA:
undetectable		 1w5uC-2psfA:
4.62
1w5uD-2psfA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		4 / 6 HIS A 142
PHE A 254
ARG A 245
GLY A 269
 None
 1.45A 2i30A-2psfA:
undetectable		 2i30A-2psfA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		4 / 5 VAL A 147
SER A 263
VAL A 267
SER A 145
 None
 1.34A 2j9cA-2psfA:
undetectable
2j9cB-2psfA:
undetectable
2j9cC-2psfA:
undetectable		 2j9cA-2psfA:
17.14
2j9cB-2psfA:
17.14
2j9cC-2psfA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_A_LDPA501_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		4 / 7 GLU A 155
GLY A 260
PHE A 254
ILE A 266
 None
 1.04A 2qmzA-2psfA:
3.1
2qmzB-2psfA:
2.8		 2qmzA-2psfA:
21.59
2qmzB-2psfA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_CHDA332_0
(CHOLOYLGLYCINE
HYDROLASE)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		5 / 12 ARG A 136
ILE A 137
PHE A 116
PHE A  49
ILE A  67
 None
 1.14A 2rlcA-2psfA:
undetectable		 2rlcA-2psfA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		4 / 6 ASP A  38
TYR A  37
PHE A 105
LEU A  50
 None
 1.02A 2w98A-2psfA:
undetectable
2w98B-2psfA:
2.6		 2w98A-2psfA:
20.41
2w98B-2psfA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		3 / 3 VAL A 175
ASN A  53
TRP A 121
 None
 1.07A 2y00B-2psfA:
undetectable		 2y00B-2psfA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		5 / 11 GLY A  82
GLY A  85
HIS A  97
PRO A 215
ILE A  79
 None
 1.22A 2y7kA-2psfA:
undetectable		 2y7kA-2psfA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		5 / 12 GLY A  82
GLY A  85
HIS A  97
PRO A 215
ILE A  79
 None
 1.32A 2y7kC-2psfA:
undetectable		 2y7kC-2psfA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1000_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		5 / 10 GLY A  82
GLY A  85
HIS A  97
PRO A 215
ILE A  79
 None
 1.27A 2y7pA-2psfA:
undetectable		 2y7pA-2psfA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		5 / 12 LEU A 125
SER A  57
ILE A  75
LEU A 101
ILE A  79
 None
 0.95A 3adxB-2psfA:
undetectable		 3adxB-2psfA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_C_VIAC901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		4 / 7 TYR A  92
HIS A  97
LEU A 176
PHE A 206
 None
 1.15A 3jwqC-2psfA:
undetectable		 3jwqC-2psfA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		3 / 3 ALA A 123
VAL A 117
TRP A  60
 None
 0.86A 3l8lC-2psfA:
undetectable
3l8lD-2psfA:
undetectable		 3l8lC-2psfA:
4.62
3l8lD-2psfA:
6.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		4 / 5 ASP A  31
SER A  32
SER A  84
GLY A  88
 None
 0.90A 3rxhA-2psfA:
undetectable		 3rxhA-2psfA:
21.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4F5Z_A_BEZA302_0
(HALOALKANE
DEHALOGENASE)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		5 / 8 ASN A  53
ASP A 120
TRP A 121
VAL A 185
HIS A 285
 None
 0.23A 4f5zA-2psfA:
39.6		 4f5zA-2psfA:
37.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4F5Z_A_BEZA302_0
(HALOALKANE
DEHALOGENASE)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		4 / 8 ASN A  53
TRP A 121
PHE A 181
VAL A 185
 None
 1.03A 4f5zA-2psfA:
39.6		 4f5zA-2psfA:
37.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		5 / 9 ILE A  15
GLY A  17
TYR A 202
GLU A 289
ARG A 192
 None
 1.25A 4yp2B-2psfA:
undetectable		 4yp2B-2psfA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		5 / 9 ILE A  15
GLY A  17
TYR A 202
GLU A 289
ARG A 192
 None
 1.24A 5cf9B-2psfA:
undetectable		 5cf9B-2psfA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA303_1
(CHITOSANASE)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		4 / 5 HIS A 128
VAL A 146
GLY A 122
ALA A 123
 None
 0.76A 5hwaA-2psfA:
undetectable		 5hwaA-2psfA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		4 / 5 ILE A 255
ILE A  67
HIS A  66
VAL A  63
 None
 0.98A 5jmnA-2psfA:
undetectable		 5jmnA-2psfA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		3 / 3 HIS A 285
LYS A 189
PHE A 261
 None
 1.24A 5klaA-2psfA:
undetectable		 5klaA-2psfA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 2psf RENILLA-LUCIFERIN
2-MONOOXYGENASE
(Renilla
reniformis) 		5 / 12 SER A 263
LEU A 253
VAL A 141
SER A 145
VAL A 281
 None
 1.41A 6a94A-2psfA:
undetectable		 6a94A-2psfA:
22.33