SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pso'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 2pso STAR-RELATED LIPID
TRANSFER PROTEIN 13
(Homo
sapiens) 		3 / 3 ASN A 936
ALA A1095
ASN A1099
 None
 0.82A 1n4fA-2psoA:
undetectable		 1n4fA-2psoA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2pso STAR-RELATED LIPID
TRANSFER PROTEIN 13
(Homo
sapiens) 		4 / 4 ALA A 955
VAL A1094
ALA A1091
HIS A1088
 None
 1.18A 1q23A-2psoA:
2.7		 1q23A-2psoA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2pso STAR-RELATED LIPID
TRANSFER PROTEIN 13
(Homo
sapiens) 		4 / 4 ALA A 955
VAL A1094
ALA A1091
HIS A1088
 None
 1.20A 1q23F-2psoA:
2.7		 1q23F-2psoA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2pso STAR-RELATED LIPID
TRANSFER PROTEIN 13
(Homo
sapiens) 		4 / 4 ALA A 955
VAL A1094
ALA A1091
HIS A1088
 None
 1.18A 1q23K-2psoA:
undetectable		 1q23K-2psoA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 2pso STAR-RELATED LIPID
TRANSFER PROTEIN 13
(Homo
sapiens) 		3 / 3 TYR A 999
ASP A 978
HIS A1068
 None
 0.93A 3e23A-2psoA:
undetectable		 3e23A-2psoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 2pso STAR-RELATED LIPID
TRANSFER PROTEIN 13
(Homo
sapiens) 		5 / 12 PRO A 963
SER A1031
ASP A1051
ILE A1069
LEU A1055
 None
 1.26A 3iv6A-2psoA:
undetectable		 3iv6A-2psoA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 2pso STAR-RELATED LIPID
TRANSFER PROTEIN 13
(Homo
sapiens) 		5 / 12 PRO A 963
SER A1031
ASP A1051
ILE A1069
LEU A1055
 None
 1.28A 3iv6C-2psoA:
undetectable		 3iv6C-2psoA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 2pso STAR-RELATED LIPID
TRANSFER PROTEIN 13
(Homo
sapiens) 		4 / 6 LEU A1032
VAL A1030
THR A1028
GLU A 988
 None
 0.90A 5tudD-2psoA:
undetectable		 5tudD-2psoA:
19.41