SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pu3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A28_A_STRA1_1 (PROGESTERONE RECEPTOR)	2pu3	ENDONUCLEASE I (Aliivibrio salmonicida)	5 / 12	LEU A 119 ASN A 118 LEU A 116 GLN A 217 MET A 177	None	1.31A	1a28A-2pu3A: undetectable	1a28A-2pu3A: 19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A28_B_STRB2_1 (PROGESTERONE RECEPTOR)	2pu3	ENDONUCLEASE I (Aliivibrio salmonicida)	5 / 12	LEU A 119 ASN A 118 LEU A 116 GLN A 217 MET A 177	None	1.27A	1a28B-2pu3A: undetectable	1a28B-2pu3A: 19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SQN_A_NDRA1001_0 (PROGESTERONE RECEPTOR)	2pu3	ENDONUCLEASE I (Aliivibrio salmonicida)	5 / 12	LEU A 119 ASN A 118 LEU A 116 GLN A 217 MET A 177	None	1.34A	1sqnA-2pu3A: undetectable	1sqnA-2pu3A: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QHF_A_ACTA509_0 (CHORISMATE SYNTHASE)	2pu3	ENDONUCLEASE I (Aliivibrio salmonicida)	3 / 3	ARG A 130 GLN A 86 PRO A 83	None CL A 302 (-3.9A) None	0.77A	2qhfA-2pu3A: undetectable	2qhfA-2pu3A: 17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDV_D_AICD374_1 (BETA-PEPTIDYL AMINOPEPTIDASE)	2pu3	ENDONUCLEASE I (Aliivibrio salmonicida)	5 / 11	LEU A 185 LEU A 175 ASN A 197 ARG A 172 ASN A 221	None	1.40A	3ndvC-2pu3A: undetectable 3ndvD-2pu3A: undetectable	3ndvC-2pu3A: 18.28 3ndvD-2pu3A: 18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UBS_A_DIFA503_1 (PENTALENIC ACID SYNTHASE)	2pu3	ENDONUCLEASE I (Aliivibrio salmonicida)	4 / 7	LEU A 185 ALA A 171 LEU A 175 ILE A 170	None	0.80A	4ubsA-2pu3A: undetectable	4ubsA-2pu3A: 17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_E_DVAE7_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	2pu3	ENDONUCLEASE I (Aliivibrio salmonicida)	3 / 3	TYR A 35 SER A 41 TRP A 78	None CL A 301 (-3.1A) None	0.74A	5n8jB-2pu3A: undetectable	5n8jB-2pu3A: 22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_O_DVAO7_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	2pu3	ENDONUCLEASE I (Aliivibrio salmonicida)	3 / 3	TYR A 35 SER A 41 TRP A 78	None CL A 301 (-3.1A) None	0.70A	5n8jA-2pu3A: undetectable	5n8jA-2pu3A: 22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_P_DVAP5_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	2pu3	ENDONUCLEASE I (Aliivibrio salmonicida)	3 / 3	TYR A 35 SER A 41 TRP A 78	None CL A 301 (-3.1A) None	0.68A	5n8jD-2pu3A: undetectable	5n8jD-2pu3A: 22.90

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1A28_A_STRA1_1","PROGESTERONE RECEPTOR","2pu3","ENDONUCLEASE I","Aliivibrio salmonicida",5,"LEU A 119;ASN A 118;LEU A 116;GLN A 217;MET A 177","None","1.31A","1a28A-2pu3A:undetectable","1a28A-2pu3A:19.27"],["1A28_B_STRB2_1","PROGESTERONE RECEPTOR","2pu3","ENDONUCLEASE I","Aliivibrio salmonicida",5,"LEU A 119;ASN A 118;LEU A 116;GLN A 217;MET A 177","None","1.27A","1a28B-2pu3A:undetectable","1a28B-2pu3A:19.27"],["1SQN_A_NDRA1001_0","PROGESTERONE RECEPTOR","2pu3","ENDONUCLEASE I","Aliivibrio salmonicida",5,"LEU A 119;ASN A 118;LEU A 116;GLN A 217;MET A 177","None","1.34A","1sqnA-2pu3A:undetectable","1sqnA-2pu3A:19.06"],["2QHF_A_ACTA509_0","CHORISMATE SYNTHASE","2pu3","ENDONUCLEASE I","Aliivibrio salmonicida",3,"ARG A 130;GLN A  86;PRO A  83","None; CL A 302 (-3.9A);None","0.77A","2qhfA-2pu3A:undetectable","2qhfA-2pu3A:17.04"],["3NDV_D_AICD374_1","BETA-PEPTIDYL AMINOPEPTIDASE;BETA-PEPTIDYL AMINOPEPTIDASE","2pu3","ENDONUCLEASE I","Aliivibrio salmonicida",5,"LEU A 185;LEU A 175;ASN A 197;ARG A 172;ASN A 221","None","1.40A","3ndvC-2pu3A:undetectable;3ndvD-2pu3A:undetectable","3ndvC-2pu3A:18.28;3ndvD-2pu3A:18.28"],["4UBS_A_DIFA503_1","PENTALENIC ACID SYNTHASE","2pu3","ENDONUCLEASE I","Aliivibrio salmonicida",4,"LEU A 185;ALA A 171;LEU A 175;ILE A 170","None","0.80A","4ubsA-2pu3A:undetectable","4ubsA-2pu3A:17.59"],["5N8J_E_DVAE7_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","2pu3","ENDONUCLEASE I","Aliivibrio salmonicida",3,"TYR A  35;SER A  41;TRP A  78","None; CL A 301 (-3.1A);None","0.74A","5n8jB-2pu3A:undetectable","5n8jB-2pu3A:22.90"],["5N8J_O_DVAO7_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","2pu3","ENDONUCLEASE I","Aliivibrio salmonicida",3,"TYR A  35;SER A  41;TRP A  78","None; CL A 301 (-3.1A);None","0.70A","5n8jA-2pu3A:undetectable","5n8jA-2pu3A:22.90"],["5N8J_P_DVAP5_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","2pu3","ENDONUCLEASE I","Aliivibrio salmonicida",3,"TYR A  35;SER A  41;TRP A  78","None; CL A 301 (-3.1A);None","0.68A","5n8jD-2pu3A:undetectable","5n8jD-2pu3A:22.90"]]