SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2puq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)		 2puq TISSUE FACTOR
(Homo
sapiens) 		3 / 3 ASP T  54
THR T  17
GLU T  24
 None
 0.81A 2zifB-2puqT:
undetectable		 2zifB-2puqT:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 2puq TISSUE FACTOR
(Homo
sapiens) 		3 / 3 LYS T  28
THR T  55
ILE T  22
 None
 0.88A 4e0fB-2puqT:
undetectable		 4e0fB-2puqT:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 2puq TISSUE FACTOR
(Homo
sapiens) 		4 / 5 GLN T 190
THR T 203
THR T 106
LEU T 143
 None
 1.30A 4lvcA-2puqT:
undetectable		 4lvcA-2puqT:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 2puq TISSUE FACTOR
(Homo
sapiens) 		4 / 5 GLN T 190
THR T 203
THR T 106
LEU T 143
 None
 1.32A 4lvcC-2puqT:
undetectable		 4lvcC-2puqT:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2puq TISSUE FACTOR
(Homo
sapiens) 		4 / 4 GLN T 190
THR T 203
THR T 106
LEU T 143
 None
 1.33A 5m5kA-2puqT:
undetectable		 5m5kA-2puqT:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2puq TISSUE FACTOR
(Homo
sapiens) 		4 / 4 GLN T 190
THR T 203
THR T 106
LEU T 143
 None
 1.34A 5m5kC-2puqT:
undetectable		 5m5kC-2puqT:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2puq TISSUE FACTOR
(Homo
sapiens) 		4 / 4 GLN T 190
THR T 203
THR T 106
LEU T 143
 None
 1.31A 5m66B-2puqT:
undetectable		 5m66B-2puqT:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_B_ADNB502_2
(-)		 2puq TISSUE FACTOR
(Homo
sapiens) 		4 / 4 GLN T 190
THR T 203
THR T 106
LEU T 143
 None
 1.24A 6f3mB-2puqT:
undetectable		 6f3mB-2puqT:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 2puq TISSUE FACTOR
(Homo
sapiens) 		4 / 5 GLN T 190
THR T 203
THR T 106
LEU T 143
 None
 1.32A 6gbnA-2puqT:
undetectable		 6gbnA-2puqT:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 2puq TISSUE FACTOR
(Homo
sapiens) 		4 / 5 GLN T 190
THR T 203
THR T 106
LEU T 143
 None
 1.31A 6gbnD-2puqT:
undetectable		 6gbnD-2puqT:
17.79