SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2puz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		5 / 12 HIS A  86
HIS A  88
HIS A 256
HIS A 279
ASP A 331
 FE  A 500 (-3.3A)
FE  A 500 (-3.3A)
FE  A 500 (-3.6A)
None
FE  A 500 (-2.8A)
 0.60A 1a4lA-2puzA:
19.2		 1a4lA-2puzA:
25.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		5 / 12 HIS A  86
HIS A 279
PHE A 228
ALA A 304
HIS A  88
 FE  A 500 (-3.3A)
None
None
None
FE  A 500 (-3.3A)
 1.26A 1a4lA-2puzA:
19.2		 1a4lA-2puzA:
25.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		5 / 12 HIS A  86
HIS A  88
HIS A 256
HIS A 279
ASP A 331
 FE  A 500 (-3.3A)
FE  A 500 (-3.3A)
FE  A 500 (-3.6A)
None
FE  A 500 (-2.8A)
 0.54A 1a4lC-2puzA:
19.1		 1a4lC-2puzA:
25.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		5 / 12 HIS A  86
HIS A 279
PHE A 228
ALA A 304
HIS A  88
 FE  A 500 (-3.3A)
None
None
None
FE  A 500 (-3.3A)
 1.24A 1a4lC-2puzA:
19.1		 1a4lC-2puzA:
25.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		4 / 8 ASP A 331
HIS A  86
HIS A 256
HIS A 279
 FE  A 500 (-2.8A)
FE  A 500 (-3.3A)
FE  A 500 (-3.6A)
None
 0.99A 1ei6D-2puzA:
undetectable		 1ei6D-2puzA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		4 / 7 LEU A 361
THR A  79
LEU A  26
GLY A  37
 None
 0.94A 1gtiA-2puzA:
undetectable		 1gtiA-2puzA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		4 / 7 THR A 151
LEU A 145
GLY A 148
LEU A 342
 None
 0.95A 1gtiE-2puzA:
undetectable		 1gtiE-2puzA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA732_1
(ALPHA AMYLASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		5 / 9 GLY A 117
GLY A 335
GLY A  93
GLY A  92
ASP A 124
 None
 0.90A 1mxdA-2puzA:
6.2		 1mxdA-2puzA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA442_1
(ALPHA AMYLASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		5 / 11 GLY A 117
GLY A 335
GLY A  93
GLY A  92
ASP A 124
 None
 0.94A 1mxgA-2puzA:
4.5		 1mxgA-2puzA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		5 / 10 THR A  87
HIS A  86
HIS A 256
HIS A 279
THR A 330
 None
FE  A 500 (-3.3A)
FE  A 500 (-3.6A)
None
None
 1.21A 1r55A-2puzA:
undetectable		 1r55A-2puzA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		4 / 8 THR A 125
GLY A  93
ARG A 140
PRO A 334
 None
 0.93A 1rxcB-2puzA:
undetectable		 1rxcB-2puzA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		4 / 8 THR A 125
GLY A  93
ARG A 140
PRO A 334
 None
 0.92A 1rxcI-2puzA:
undetectable		 1rxcI-2puzA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		4 / 8 THR A 125
GLY A  93
ARG A 140
PRO A 334
 None
 0.94A 1rxcK-2puzA:
undetectable		 1rxcK-2puzA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		5 / 11 GLY A 212
PRO A 211
TYR A 204
ILE A 205
VAL A 242
 None
 1.29A 1tmxA-2puzA:
undetectable		 1tmxA-2puzA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		5 / 12 GLY A 212
PRO A 211
TYR A 204
ILE A 205
VAL A 242
 None
 1.26A 1tmxB-2puzA:
undetectable		 1tmxB-2puzA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_A_ACTA4901_0
(PYRANOSE OXIDASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		4 / 6 THR A 336
GLN A 259
PHE A 228
HIS A 191
 None
 0.89A 1tt0A-2puzA:
0.0		 1tt0A-2puzA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_B_ACTB3901_0
(PYRANOSE OXIDASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		4 / 6 THR A 336
GLN A 259
PHE A 228
HIS A 191
 None
 0.87A 1tt0B-2puzA:
0.0		 1tt0B-2puzA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_C_ACTC6901_0
(PYRANOSE OXIDASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		4 / 6 THR A 336
GLN A 259
PHE A 228
HIS A 191
 None
 0.86A 1tt0C-2puzA:
0.0		 1tt0C-2puzA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_D_ACTD5901_0
(PYRANOSE OXIDASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		4 / 6 THR A 336
GLN A 259
PHE A 228
HIS A 191
 None
 0.87A 1tt0D-2puzA:
0.0		 1tt0D-2puzA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		3 / 3 GLU A 230
GLU A 238
LEU A 268
 None
 0.72A 1v8bA-2puzA:
2.4		 1v8bA-2puzA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		5 / 12 LEU A 144
LEU A 141
LEU A 138
ALA A 137
THR A 330
 None
 0.97A 1ya3C-2puzA:
undetectable		 1ya3C-2puzA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A5H_A_SAMA417_0
(L-LYSINE
2,3-AMINOMUTASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		5 / 11 HIS A  86
THR A 330
HIS A  88
CYH A  85
ASP A  84
 FE  A 500 (-3.3A)
None
FE  A 500 (-3.3A)
None
None
 1.17A 2a5hA-2puzA:
4.4		 2a5hA-2puzA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A5H_B_SAMB417_0
(L-LYSINE
2,3-AMINOMUTASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		5 / 12 HIS A  86
THR A 330
HIS A  88
CYH A  85
ASP A  84
 FE  A 500 (-3.3A)
None
FE  A 500 (-3.3A)
None
None
 1.16A 2a5hB-2puzA:
2.5		 2a5hB-2puzA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A5H_C_SAMC417_0
(L-LYSINE
2,3-AMINOMUTASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		5 / 12 HIS A  86
THR A 330
HIS A  88
CYH A  85
ASP A  84
 FE  A 500 (-3.3A)
None
FE  A 500 (-3.3A)
None
None
 1.17A 2a5hC-2puzA:
3.8		 2a5hC-2puzA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A5H_D_SAMD417_0
(L-LYSINE
2,3-AMINOMUTASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		5 / 12 HIS A  86
THR A 330
HIS A  88
CYH A  85
ASP A  84
 FE  A 500 (-3.3A)
None
FE  A 500 (-3.3A)
None
None
 1.17A 2a5hD-2puzA:
4.3		 2a5hD-2puzA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_2
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		3 / 3 VAL A 181
VAL A 184
ASP A 130
 None
 0.74A 2fumD-2puzA:
undetectable		 2fumD-2puzA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		3 / 3 HIS A 256
HIS A  86
HIS A  88
 FE  A 500 (-3.6A)
FE  A 500 (-3.3A)
FE  A 500 (-3.3A)
 0.55A 3qpkA-2puzA:
undetectable		 3qpkA-2puzA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		3 / 3 HIS A 256
HIS A  86
HIS A  88
 FE  A 500 (-3.6A)
FE  A 500 (-3.3A)
FE  A 500 (-3.3A)
 0.57A 3qpkB-2puzA:
undetectable		 3qpkB-2puzA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		4 / 8 THR A 125
GLY A  93
ARG A 140
PRO A 334
 None
 0.94A 4e1vA-2puzA:
undetectable		 4e1vA-2puzA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		4 / 8 THR A 125
GLY A  93
ARG A 140
PRO A 334
 None
 0.98A 4e1vE-2puzA:
undetectable		 4e1vE-2puzA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		5 / 12 LEU A 144
LEU A 141
LEU A 138
ALA A 137
ALA A 172
 None
 1.02A 4fn9A-2puzA:
undetectable		 4fn9A-2puzA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		5 / 12 LEU A 144
LEU A 141
LEU A 138
ALA A 172
THR A 330
 None
 1.07A 4fn9A-2puzA:
undetectable		 4fn9A-2puzA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		5 / 12 LEU A 144
LEU A 141
LEU A 138
ALA A 137
THR A 330
 None
 1.17A 4fn9B-2puzA:
undetectable		 4fn9B-2puzA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2G_A_ADNA603_1
(5'-NUCLEOTIDASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		5 / 9 ASN A  23
GLY A  74
GLY A  75
ARG A  76
ASP A  72
 None
 1.43A 4h2gA-2puzA:
undetectable		 4h2gA-2puzA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA303_1
(CHITOSANASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		4 / 6 GLU A 165
THR A 125
HIS A 191
TYR A 204
 None
 0.90A 4qwpA-2puzA:
undetectable		 4qwpA-2puzA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		5 / 12 HIS A  88
HIS A 256
HIS A 279
LEU A 308
ASP A 331
 FE  A 500 (-3.3A)
FE  A 500 (-3.6A)
None
None
FE  A 500 (-2.8A)
 0.87A 4r88A-2puzA:
35.4		 4r88A-2puzA:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		4 / 8 ALA A 277
ALA A 270
ALA A 324
ALA A 298
 None
 0.72A 4twdF-2puzA:
undetectable
4twdG-2puzA:
undetectable
4twdH-2puzA:
undetectable
4twdI-2puzA:
undetectable
4twdJ-2puzA:
undetectable		 4twdF-2puzA:
20.23
4twdG-2puzA:
20.23
4twdH-2puzA:
20.23
4twdI-2puzA:
20.23
4twdJ-2puzA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		4 / 8 ALA A 324
ALA A 298
ALA A 277
ALA A 270
 None
 0.73A 4twdF-2puzA:
undetectable
4twdG-2puzA:
undetectable
4twdH-2puzA:
undetectable
4twdI-2puzA:
undetectable
4twdJ-2puzA:
undetectable		 4twdF-2puzA:
20.23
4twdG-2puzA:
20.23
4twdH-2puzA:
20.23
4twdI-2puzA:
20.23
4twdJ-2puzA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		5 / 9 ALA A 290
ALA A 294
GLY A 264
GLY A 265
ALA A 266
 None
 1.08A 5d0xK-2puzA:
undetectable
5d0xL-2puzA:
undetectable		 5d0xK-2puzA:
19.76
5d0xL-2puzA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		5 / 9 ALA A 290
ALA A 294
GLY A 264
GLY A 265
ALA A 266
 None
 1.09A 5d0xY-2puzA:
undetectable
5d0xZ-2puzA:
undetectable		 5d0xY-2puzA:
19.76
5d0xZ-2puzA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_B_BEZB1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		4 / 6 GLY A 335
THR A 336
SER A 121
HIS A 191
 None
 0.93A 5ewuB-2puzA:
undetectable		 5ewuB-2puzA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		3 / 3 HIS A 256
HIS A  86
HIS A  88
 FE  A 500 (-3.6A)
FE  A 500 (-3.3A)
FE  A 500 (-3.3A)
 0.47A 5migA-2puzA:
undetectable		 5migA-2puzA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		3 / 3 LYS A 155
HIS A  86
HIS A  88
 None
FE  A 500 (-3.3A)
FE  A 500 (-3.3A)
 1.42A 5oexD-2puzA:
undetectable		 5oexD-2puzA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_1
(ALPHA-AMYLASE)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		3 / 3 TYR A 282
ALA A 304
LEU A 308
 None
 0.68A 6ag0C-2puzA:
6.3		 6ag0C-2puzA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		4 / 5 ARG A 249
ALA A 216
TYR A 187
ILE A 162
 None
 1.15A 6f6sA-2puzA:
undetectable
6f6sB-2puzA:
undetectable		 6f6sA-2puzA:
15.04
6f6sB-2puzA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 2puz IMIDAZOLONEPROPIONAS
E
(Agrobacterium
fabrum) 		4 / 5 ARG A 249
ALA A 216
TYR A 187
ILE A 162
 None
 1.20A 6g9bA-2puzA:
undetectable
6g9bB-2puzA:
undetectable		 6g9bA-2puzA:
15.04
6g9bB-2puzA:
11.92