SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pv3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 2pv3 CHAPERONE SURA
(Escherichia
coli) 		4 / 6 VAL A 256
GLY A 257
ALA A 246
LEU A 247
 None
 0.58A 1e7bB-2pv3A:
3.0		 1e7bB-2pv3A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_A_ID2A1_0
(THYMIDINE KINASE)		 2pv3 CHAPERONE SURA
(Escherichia
coli) 		5 / 12 GLU A 416
ILE A  80
ALA A 421
ARG A 149
GLU A 145
 None
 1.38A 1ki7A-2pv3A:
undetectable		 1ki7A-2pv3A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2pv3 CHAPERONE SURA
(Escherichia
coli) 		4 / 8 PHE A 406
SER A 412
MET A 414
TRP A 413
 None
 1.32A 3jx1A-2pv3A:
undetectable
3jx1B-2pv3A:
undetectable		 3jx1A-2pv3A:
22.59
3jx1B-2pv3A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2pv3 CHAPERONE SURA
(Escherichia
coli) 		4 / 8 PHE A 406
SER A 412
MET A 414
TRP A 413
 None
 1.33A 3nlyA-2pv3A:
undetectable
3nlyB-2pv3A:
undetectable		 3nlyA-2pv3A:
22.59
3nlyB-2pv3A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2pv3 CHAPERONE SURA
(Escherichia
coli) 		4 / 8 PHE A 406
SER A 412
MET A 414
TRP A 413
 None
 1.35A 3rqlA-2pv3A:
undetectable
3rqlB-2pv3A:
undetectable		 3rqlA-2pv3A:
22.59
3rqlB-2pv3A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2pv3 CHAPERONE SURA
(Escherichia
coli) 		4 / 8 PHE A 406
SER A 412
MET A 414
TRP A 413
 None
 1.34A 4d32A-2pv3A:
undetectable
4d32B-2pv3A:
undetectable		 4d32A-2pv3A:
22.59
4d32B-2pv3A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 2pv3 CHAPERONE SURA
(Escherichia
coli) 		5 / 11 ILE A 179
ALA A 216
GLY A 213
GLY A 232
ASN A 175
 None
 1.12A 4jdsA-2pv3A:
undetectable		 4jdsA-2pv3A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)		 2pv3 CHAPERONE SURA
(Escherichia
coli) 		4 / 7 GLN A  85
GLY A  84
GLN A  95
ASP A  77
 None
 1.10A 5vlmE-2pv3A:
2.5		 5vlmE-2pv3A:
21.40