SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pv4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_A_9PLA1_1
(CYTOCHROME P450 2A13)		 2pv4 UNCHARACTERIZED
PROTEIN
(Shewanella
amazonensis) 		5 / 9 PHE A  72
PHE A  75
ALA A  78
ASN A  79
ALA A 117
 None
 1.34A 3t3sA-2pv4A:
undetectable		 3t3sA-2pv4A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 2pv4 UNCHARACTERIZED
PROTEIN
(Shewanella
amazonensis) 		5 / 8 PHE A  72
PHE A  75
ALA A  78
ASN A  79
ALA A 117
 None
 1.32A 3t3sD-2pv4A:
undetectable		 3t3sD-2pv4A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)		 2pv4 UNCHARACTERIZED
PROTEIN
(Shewanella
amazonensis) 		5 / 8 PHE A  72
PHE A  75
ALA A  78
ASN A  79
ALA A 117
 None
 1.40A 3t3sF-2pv4A:
undetectable		 3t3sF-2pv4A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 2pv4 UNCHARACTERIZED
PROTEIN
(Shewanella
amazonensis) 		4 / 7 LEU A  26
TYR A  37
ALA A  78
ILE A  82
 None
 0.67A 4y03A-2pv4A:
undetectable		 4y03A-2pv4A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 2pv4 UNCHARACTERIZED
PROTEIN
(Shewanella
amazonensis) 		4 / 5 LEU A  26
TYR A  37
ALA A  78
ILE A  82
 None
 0.93A 4y03B-2pv4A:
undetectable		 4y03B-2pv4A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		 2pv4 UNCHARACTERIZED
PROTEIN
(Shewanella
amazonensis) 		4 / 6 LEU A 125
PHE A  72
ILE A 144
PHE A  67
 None
 1.23A 4y4dA-2pv4A:
undetectable		 4y4dA-2pv4A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 2pv4 UNCHARACTERIZED
PROTEIN
(Shewanella
amazonensis) 		4 / 7 THR A  53
PHE A  52
HIS A  73
ARG A   9
 None
None
None
GOL  A 145 (-4.3A)
 0.91A 6jnhA-2pv4A:
undetectable		 6jnhA-2pv4A:
23.76