SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pvq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1867_0
(FPRA)		 2pvq GLUTATHIONE
S-TRANSFERASE
(Ochrobactrum
anthropi) 		4 / 4 ALA A  92
ARG A  93
GLN A  95
GLU A  96
 None
SO4  A5001 (-4.0A)
None
None
 1.41A 1lqtB-2pvqA:
undetectable		 1lqtB-2pvqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1424_0
(FPRA)		 2pvq GLUTATHIONE
S-TRANSFERASE
(Ochrobactrum
anthropi) 		4 / 4 ALA A  92
ARG A  93
GLN A  95
GLU A  96
 None
SO4  A5001 (-4.0A)
None
None
 1.42A 1lquB-2pvqA:
undetectable		 1lquB-2pvqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2pvq GLUTATHIONE
S-TRANSFERASE
(Ochrobactrum
anthropi) 		5 / 12 LEU A  18
ALA A 194
GLU A 198
LEU A  12
LEU A  70
 None
 0.96A 1s9pA-2pvqA:
undetectable		 1s9pA-2pvqA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 2pvq GLUTATHIONE
S-TRANSFERASE
(Ochrobactrum
anthropi) 		5 / 12 LEU A  70
ILE A  17
ALA A  81
PHE A  82
ASP A 155
 None
 1.07A 2qb4A-2pvqA:
undetectable		 2qb4A-2pvqA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 2pvq GLUTATHIONE
S-TRANSFERASE
(Ochrobactrum
anthropi) 		5 / 11 LEU A  70
ILE A  17
ALA A  81
PHE A  82
ASP A 155
 None
 1.13A 2qjuA-2pvqA:
undetectable		 2qjuA-2pvqA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2pvq GLUTATHIONE
S-TRANSFERASE
(Ochrobactrum
anthropi) 		5 / 12 LEU A 132
LEU A 139
PHE A 108
ILE A 161
GLY A 163
 None
 0.85A 3kk6A-2pvqA:
undetectable		 3kk6A-2pvqA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2pvq GLUTATHIONE
S-TRANSFERASE
(Ochrobactrum
anthropi) 		5 / 12 LEU A 132
LEU A 139
PHE A 108
ILE A 161
GLY A 163
 None
 0.88A 3kk6B-2pvqA:
0.9		 3kk6B-2pvqA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2pvq GLUTATHIONE
S-TRANSFERASE
(Ochrobactrum
anthropi) 		5 / 12 LEU A 132
LEU A 139
PHE A 108
ILE A 161
GLY A 163
 None
 0.86A 3n8xB-2pvqA:
undetectable		 3n8xB-2pvqA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2pvq GLUTATHIONE
S-TRANSFERASE
(Ochrobactrum
anthropi) 		4 / 5 VAL A 185
LEU A 186
ILE A 162
ALA A 158
 None
 1.01A 3n8yB-2pvqA:
undetectable		 3n8yB-2pvqA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2pvq GLUTATHIONE
S-TRANSFERASE
(Ochrobactrum
anthropi) 		4 / 4 GLY A   8
TRP A 164
VAL A 160
SER A  11
 GSH  A5204 (-3.5A)
GSH  A5204 (-4.0A)
None
None
 1.49A 4d39A-2pvqA:
0.2		 4d39A-2pvqA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 2pvq GLUTATHIONE
S-TRANSFERASE
(Ochrobactrum
anthropi) 		3 / 3 TYR A   4
THR A  37
GLU A  26
 None
 0.81A 4df3A-2pvqA:
undetectable		 4df3A-2pvqA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 2pvq GLUTATHIONE
S-TRANSFERASE
(Ochrobactrum
anthropi) 		3 / 3 TYR A   4
THR A  37
GLU A  26
 None
 0.84A 4df3B-2pvqA:
undetectable		 4df3B-2pvqA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 2pvq GLUTATHIONE
S-TRANSFERASE
(Ochrobactrum
anthropi) 		4 / 8 LEU A 200
HIS A  15
LEU A 186
ILE A  16
 None
 0.88A 5v0vA-2pvqA:
undetectable		 5v0vA-2pvqA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA410_0
(UNCHARACTERIZED
PROTEIN KDOO)		 2pvq GLUTATHIONE
S-TRANSFERASE
(Ochrobactrum
anthropi) 		4 / 4 GLY A 199
LEU A 200
VAL A   7
GLU A 198
 None
 1.28A 5yw0A-2pvqA:
undetectable		 5yw0A-2pvqA:
22.88