SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pwh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		3 / 3 TRP A 318
VAL A  11
TRP A   7
 None
 1.28A 1c4dA-2pwhA:
undetectable
1c4dB-2pwhA:
undetectable		 1c4dA-2pwhA:
1.82
1c4dB-2pwhA:
1.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		5 / 12 TYR A  64
ASP A 200
HIS A 326
ASP A 327
ARG A 418
 None
 0.72A 1dedA-2pwhA:
27.9		 1dedA-2pwhA:
26.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		7 / 12 TYR A  64
ARG A 198
ASP A 200
GLU A 254
HIS A 326
ASP A 327
ARG A 418
 None
 0.78A 1dedB-2pwhA:
27.5		 1dedB-2pwhA:
26.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_2
(ESTROGEN RECEPTOR)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		4 / 6 LEU A 178
ASP A 174
MET A 239
LEU A 186
 None
 1.18A 1errB-2pwhA:
undetectable		 1errB-2pwhA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		5 / 11 ILE A  28
GLY A 434
GLY A  25
PHE A 431
ASP A  22
 None
None
None
None
CA  A7001 (-3.0A)
 1.02A 1ho5A-2pwhA:
undetectable		 1ho5A-2pwhA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		8 / 12 TYR A  64
HIS A 104
PHE A 164
ARG A 198
ASP A 200
GLU A 254
HIS A 326
ASP A 327
 None
 0.95A 1mxdA-2pwhA:
22.9		 1mxdA-2pwhA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		4 / 6 TYR A  64
ASP A  61
PHE A 164
THR A 201
 None
 1.13A 2dttB-2pwhA:
undetectable
2dttC-2pwhA:
undetectable		 2dttB-2pwhA:
11.68
2dttC-2pwhA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQY_A_ADNA400_1
(MEMBRANE LIPOPROTEIN
TMPC)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		5 / 12 ASP A 384
PHE A 390
PHE A 222
PHE A 145
GLY A 146
 None
 1.25A 2fqyA-2pwhA:
undetectable		 2fqyA-2pwhA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA6_A_SCKA902_1
(ACETYLCHOLINESTERASE)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		5 / 10 ASN A 325
GLU A 368
LEU A  44
LEU A  41
TYR A  40
 None
 1.41A 2ha6A-2pwhA:
undetectable		 2ha6A-2pwhA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_2
(ESTROGEN RECEPTOR)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		4 / 5 LEU A 178
ASP A 174
MET A 239
LEU A 186
 None
 1.19A 2jfaA-2pwhA:
undetectable		 2jfaA-2pwhA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_A_CLUA808_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		4 / 7 ALA A 149
TYR A 163
TYR A 141
MET A 219
 None
 1.32A 2pncA-2pwhA:
undetectable		 2pncA-2pwhA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_2
(ESTROGEN RECEPTOR)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		4 / 5 LEU A 171
ASP A 174
MET A 239
LEU A 186
 None
 1.27A 2qxsA-2pwhA:
undetectable		 2qxsA-2pwhA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_2
(ESTROGEN RECEPTOR)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		4 / 5 LEU A 178
ASP A 174
MET A 239
LEU A 186
 None
 1.18A 2qxsA-2pwhA:
undetectable		 2qxsA-2pwhA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_2
(ESTROGEN RECEPTOR)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		4 / 5 LEU A 178
ASP A 174
MET A 239
LEU A 186
 None
 1.20A 2qxsB-2pwhA:
undetectable		 2qxsB-2pwhA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		6 / 12 ARG A 198
ASP A 200
GLU A 254
HIS A 326
ASP A 327
ASP A  61
 None
 0.72A 3aicA-2pwhA:
4.8		 3aicA-2pwhA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		6 / 12 ARG A 198
ASP A 200
GLU A 254
HIS A 326
ASP A 327
ASP A  61
 None
 0.73A 3aicB-2pwhA:
7.4		 3aicB-2pwhA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		7 / 12 ARG A 198
ASP A 200
GLU A 254
HIS A 326
ASP A 327
ASP A  61
TYR A  64
 None
 0.70A 3aicC-2pwhA:
5.3		 3aicC-2pwhA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		6 / 12 ARG A 198
ASP A 200
GLU A 254
HIS A 326
ASP A 327
ASP A  61
 None
 0.80A 3aicD-2pwhA:
7.5		 3aicD-2pwhA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		6 / 12 ARG A 198
ASP A 200
GLU A 254
HIS A 326
ASP A 327
ASP A  61
 None
 0.79A 3aicE-2pwhA:
7.5		 3aicE-2pwhA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		6 / 12 ARG A 198
ASP A 200
GLU A 254
HIS A 326
ASP A 327
ASP A  61
 None
 0.77A 3aicF-2pwhA:
3.3		 3aicF-2pwhA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		6 / 12 ARG A 198
ASP A 200
GLU A 254
HIS A 326
ASP A 327
ASP A  61
 None
 0.74A 3aicG-2pwhA:
4.0		 3aicG-2pwhA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		6 / 12 ARG A 198
ASP A 200
GLU A 254
HIS A 326
ASP A 327
ASP A  61
 None
 0.77A 3aicH-2pwhA:
7.4		 3aicH-2pwhA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		4 / 8 LEU A 171
ILE A 102
PHE A 199
ARG A 179
 None
 0.82A 3b9lA-2pwhA:
undetectable		 3b9lA-2pwhA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		4 / 5 PRO A  53
ILE A  51
PRO A  17
TYR A  16
 None
 1.07A 3d9lA-2pwhA:
1.2
3d9lY-2pwhA:
undetectable		 3d9lA-2pwhA:
13.13
3d9lY-2pwhA:
2.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_1
(PROTEASE)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		5 / 11 GLY A  45
ASP A  47
ILE A 469
THR A 354
ILE A 363
 None
 0.88A 3ekxA-2pwhA:
undetectable		 3ekxA-2pwhA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		5 / 10 GLY A 196
ALA A 249
ASP A 248
LEU A 274
VAL A 243
 None
 0.89A 3em3A-2pwhA:
undetectable		 3em3A-2pwhA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		3 / 3 TRP A 342
VAL A 332
TRP A 549
 None
 1.16A 3zq8C-2pwhA:
undetectable
3zq8D-2pwhA:
undetectable		 3zq8C-2pwhA:
1.82
3zq8D-2pwhA:
1.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		4 / 5 TYR A  13
LEU A  44
TYR A 460
LEU A 369
 None
 1.36A 4em2A-2pwhA:
0.0		 4em2A-2pwhA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		4 / 8 ASP A 384
ASP A  61
GLU A 386
ASP A 200
 None
 1.12A 4gkiE-2pwhA:
4.2
4gkiG-2pwhA:
4.7		 4gkiE-2pwhA:
19.92
4gkiG-2pwhA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		4 / 7 ILE A 484
PHE A 516
LEU A 504
THR A 352
 None
 0.79A 4mmcA-2pwhA:
undetectable		 4mmcA-2pwhA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		5 / 12 VAL A 387
SER A 143
PHE A 145
ASP A  61
GLY A 146
 None
 1.50A 4pevA-2pwhA:
undetectable		 4pevA-2pwhA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		4 / 8 TYR A 226
PHE A 222
GLY A 146
ILE A 385
 None
 0.85A 4qoiA-2pwhA:
undetectable
4qoiB-2pwhA:
undetectable		 4qoiA-2pwhA:
18.26
4qoiB-2pwhA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		5 / 9 ALA A 351
ALA A 349
SER A 551
ALA A 345
SER A 532
 None
 1.25A 4twdA-2pwhA:
undetectable
4twdB-2pwhA:
undetectable
4twdC-2pwhA:
undetectable
4twdD-2pwhA:
undetectable
4twdE-2pwhA:
undetectable		 4twdA-2pwhA:
19.58
4twdB-2pwhA:
19.58
4twdC-2pwhA:
19.58
4twdD-2pwhA:
19.58
4twdE-2pwhA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		4 / 5 THR A 432
GLY A 430
GLU A  36
ASP A  22
 None
None
None
CA  A7001 (-3.0A)
 1.00A 5c0oH-2pwhA:
undetectable		 5c0oH-2pwhA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		6 / 12 ARG A 198
ASP A 200
GLU A 254
GLY A 257
HIS A 326
ASP A 327
 None
 0.68A 5csyB-2pwhA:
4.0		 5csyB-2pwhA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		4 / 6 TYR A 463
TYR A  40
GLY A 370
ASP A 338
 None
 1.34A 5emlA-2pwhA:
5.7		 5emlA-2pwhA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		3 / 3 THR A 432
ASP A  30
GLU A  36
 None
CA  A7001 (-3.3A)
None
 0.83A 5fa8A-2pwhA:
undetectable		 5fa8A-2pwhA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		5 / 12 GLY A 253
GLU A 238
ALA A 249
ILE A 102
TYR A 205
 None
 1.25A 5igvA-2pwhA:
3.5		 5igvA-2pwhA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		4 / 4 ASN A 373
ILE A 295
TYR A 285
PHE A 280
 None
 1.42A 5igvA-2pwhA:
3.4		 5igvA-2pwhA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		3 / 3 GLY A  63
THR A  35
PRO A  17
 None
 0.60A 5v5zA-2pwhA:
undetectable		 5v5zA-2pwhA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_B_C2FB702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		5 / 12 ASN A  59
GLY A  63
GLY A  29
SER A  19
ILE A  28
 None
None
CA  A7001 ( 4.6A)
None
None
 1.16A 5vooB-2pwhA:
10.5		 5vooB-2pwhA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		5 / 12 ASN A  59
GLY A  63
GLY A  29
SER A  19
ILE A  28
 None
None
CA  A7001 ( 4.6A)
None
None
 1.12A 5vooD-2pwhA:
10.4		 5vooD-2pwhA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_F_C2FF3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		5 / 12 ASN A  59
GLY A  63
GLY A  29
SER A  19
ILE A  28
 None
None
CA  A7001 ( 4.6A)
None
None
 1.13A 5vooF-2pwhA:
9.3		 5vooF-2pwhA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_1
(MRNA CAPPING ENZYME
P5)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		3 / 3 TYR A 374
ASP A 415
ASP A 381
 None
 0.76A 5x6yA-2pwhA:
undetectable		 5x6yA-2pwhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		3 / 3 ASP A 393
PHE A 222
ARG A 291
 None
 1.03A 5yw0A-2pwhA:
undetectable		 5yw0A-2pwhA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		5 / 12 TYR A  64
HIS A 104
ASP A 200
HIS A 326
ASP A 327
 None
 0.47A 6ag0A-2pwhA:
19.8		 6ag0A-2pwhA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FTP_B_DM2B501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		5 / 9 LEU A 518
SER A 543
PHE A 516
LEU A 546
ASN A 488
 None
 1.38A 6ftpA-2pwhA:
0.0
6ftpB-2pwhA:
undetectable		 6ftpA-2pwhA:
10.33
6ftpB-2pwhA:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_A_68HA504_0
(BETA-1 ADRENERGIC
RECEPTOR)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		5 / 12 ASP A 327
PHE A 256
PHE A 164
PHE A 145
TYR A  64
 None
 1.34A 6h7mA-2pwhA:
undetectable		 6h7mA-2pwhA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		5 / 12 ASP A 327
PHE A 256
PHE A 164
PHE A 145
TYR A  64
 None
 1.33A 6h7mB-2pwhA:
undetectable		 6h7mB-2pwhA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_B_STIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		4 / 7 VAL A 309
ILE A 267
GLY A 229
ALA A 258
 None
 0.67A 6hd6B-2pwhA:
undetectable		 6hd6B-2pwhA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		4 / 7 TRP A 189
HIS A  54
ARG A 198
ASP A  99
 None
 1.28A 6mn4E-2pwhA:
undetectable		 6mn4E-2pwhA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 2pwh SUCROSE ISOMERASE
([Pseudomonas]
mesoacidophila) 		4 / 7 GLY A  29
HIS A 326
ASN A  52
GLY A  63
 CA  A7001 ( 4.6A)
None
None
None
 0.94A 6n7fA-2pwhA:
undetectable		 6n7fA-2pwhA:
8.63