SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pwj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 2pwj MITOCHONDRIAL
PEROXIREDOXIN
(Pisum
sativum) 		4 / 8 PRO A  52
THR A  56
CYH A  59
ARG A 137
 None
 0.47A 1h4oB-2pwjA:
26.3		 1h4oB-2pwjA:
35.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 2pwj MITOCHONDRIAL
PEROXIREDOXIN
(Pisum
sativum) 		4 / 8 PRO A  52
THR A  56
CYH A  59
ARG A 137
 None
 0.51A 1h4oG-2pwjA:
26.3		 1h4oG-2pwjA:
35.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 2pwj MITOCHONDRIAL
PEROXIREDOXIN
(Pisum
sativum) 		3 / 3 THR A  23
PRO A  36
THR A  34
 None
 0.88A 1i3wE-2pwjA:
undetectable		 1i3wE-2pwjA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUO_A_ADNA1_1
(AURORA-RELATED
KINASE 1)		 2pwj MITOCHONDRIAL
PEROXIREDOXIN
(Pisum
sativum) 		6 / 9 GLY A 145
VAL A 142
ALA A 140
LEU A 122
ALA A  12
LEU A 120
 None
 1.29A 1muoA-2pwjA:
undetectable		 1muoA-2pwjA:
19.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 2pwj MITOCHONDRIAL
PEROXIREDOXIN
(Pisum
sativum) 		4 / 8 PRO A  52
THR A  56
CYH A  59
ARG A 137
 None
 0.52A 1oc3A-2pwjA:
26.2		 1oc3A-2pwjA:
33.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2pwj MITOCHONDRIAL
PEROXIREDOXIN
(Pisum
sativum) 		5 / 11 PHE A 116
SER A 119
SER A  17
LEU A 150
VAL A 152
 None
 1.43A 1q23L-2pwjA:
undetectable		 1q23L-2pwjA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 2pwj MITOCHONDRIAL
PEROXIREDOXIN
(Pisum
sativum) 		4 / 8 PRO A  52
THR A  56
VAL A  58
ARG A 137
 None
 0.72A 2v32C-2pwjA:
17.0
2v32D-2pwjA:
18.1		 2v32C-2pwjA:
22.92
2v32D-2pwjA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 2pwj MITOCHONDRIAL
PEROXIREDOXIN
(Pisum
sativum) 		4 / 8 PRO A  52
THR A  56
VAL A  58
ARG A 137
 None
 0.69A 2v41C-2pwjA:
17.9
2v41D-2pwjA:
18.4		 2v41C-2pwjA:
22.92
2v41D-2pwjA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 2pwj MITOCHONDRIAL
PEROXIREDOXIN
(Pisum
sativum) 		4 / 8 PRO A  52
THR A  56
VAL A  58
ARG A 137
 None
 0.72A 2v41C-2pwjA:
17.9
2v41D-2pwjA:
18.4		 2v41C-2pwjA:
22.92
2v41D-2pwjA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 2pwj MITOCHONDRIAL
PEROXIREDOXIN
(Pisum
sativum) 		4 / 8 PRO A  52
THR A  56
VAL A  58
ARG A 137
 None
 0.72A 2v41G-2pwjA:
16.8
2v41H-2pwjA:
16.9		 2v41G-2pwjA:
22.92
2v41H-2pwjA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_1
(RENIN)		 2pwj MITOCHONDRIAL
PEROXIREDOXIN
(Pisum
sativum) 		5 / 12 ASP A 111
GLY A 114
SER A 119
VAL A  85
ALA A  21
 None
 1.15A 3d91B-2pwjA:
undetectable		 3d91B-2pwjA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2pwj MITOCHONDRIAL
PEROXIREDOXIN
(Pisum
sativum) 		5 / 12 ASN A 151
GLY A 163
ALA A 164
ILE A 106
VAL A  47
 None
 1.05A 4nkxA-2pwjA:
undetectable		 4nkxA-2pwjA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 2pwj MITOCHONDRIAL
PEROXIREDOXIN
(Pisum
sativum) 		5 / 11 GLN A  19
ASN A  38
VAL A 142
ASP A 144
TYR A 141
 None
 1.49A 5jh7B-2pwjA:
undetectable		 5jh7B-2pwjA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_F_RBFF201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 2pwj MITOCHONDRIAL
PEROXIREDOXIN
(Pisum
sativum) 		4 / 7 VAL A  46
TYR A 109
GLU A 107
SER A  81
 None
 0.87A 5umwA-2pwjA:
undetectable
5umwF-2pwjA:
undetectable		 5umwA-2pwjA:
18.56
5umwF-2pwjA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 2pwj MITOCHONDRIAL
PEROXIREDOXIN
(Pisum
sativum) 		4 / 5 LEU A 150
VAL A 152
GLU A 136
LEU A 122
 None
 1.07A 5xooB-2pwjA:
undetectable		 5xooB-2pwjA:
18.07