SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pww'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2pww UNCHARACTERIZED
PROTEIN
(Bacillus
clausii) 		5 / 12 GLU A  88
GLY A  49
PHE A  51
PHE A  94
LEU A  78
 None
 1.18A 4hytA-2pwwA:
undetectable		 4hytA-2pwwA:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_C_OBNC2004_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2pww UNCHARACTERIZED
PROTEIN
(Bacillus
clausii) 		5 / 12 GLU A  88
GLY A  49
PHE A  51
PHE A  94
LEU A  78
 None
 1.19A 4hytC-2pwwA:
undetectable		 4hytC-2pwwA:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2pww UNCHARACTERIZED
PROTEIN
(Bacillus
clausii) 		4 / 5 ILE A  99
LEU A   1
ASP A   5
VAL A  55
 None
 0.87A 4nkxB-2pwwA:
undetectable		 4nkxB-2pwwA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2pww UNCHARACTERIZED
PROTEIN
(Bacillus
clausii) 		4 / 7 VAL A  71
ILE A  73
VAL A  38
ALA A  57
 None
 0.58A 5ospA-2pwwA:
undetectable		 5ospA-2pwwA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2pww UNCHARACTERIZED
PROTEIN
(Bacillus
clausii) 		4 / 7 VAL A  71
ILE A  73
VAL A  38
ALA A  57
 None
 0.58A 5osrA-2pwwA:
undetectable		 5osrA-2pwwA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2pww UNCHARACTERIZED
PROTEIN
(Bacillus
clausii) 		4 / 6 ILE A 113
ILE A  77
LEU A  53
PHE A  27
 None
 0.81A 5vkqA-2pwwA:
undetectable
5vkqB-2pwwA:
undetectable		 5vkqA-2pwwA:
5.08
5vkqB-2pwwA:
5.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2pww UNCHARACTERIZED
PROTEIN
(Bacillus
clausii) 		4 / 6 ILE A 113
ILE A  77
LEU A  53
PHE A  27
 None
 0.80A 5vkqB-2pwwA:
undetectable
5vkqC-2pwwA:
undetectable		 5vkqB-2pwwA:
5.08
5vkqC-2pwwA:
5.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2pww UNCHARACTERIZED
PROTEIN
(Bacillus
clausii) 		4 / 6 ILE A 113
ILE A  77
LEU A  53
PHE A  27
 None
 0.79A 5vkqC-2pwwA:
undetectable
5vkqD-2pwwA:
undetectable		 5vkqC-2pwwA:
5.08
5vkqD-2pwwA:
5.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2pww UNCHARACTERIZED
PROTEIN
(Bacillus
clausii) 		4 / 6 ILE A 113
ILE A  77
LEU A  53
PHE A  27
 None
 0.79A 5vkqA-2pwwA:
undetectable
5vkqD-2pwwA:
undetectable		 5vkqA-2pwwA:
5.08
5vkqD-2pwwA:
5.08