SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2py0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_D_SC2D1290_1
(FICOLIN-2)		 2py0 FIMBRIAL PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 GLY A 125
TRP A 127
ARG A 120
LEU A 126
 None
 1.24A 2j2pD-2py0A:
undetectable
2j2pF-2py0A:
undetectable		 2j2pD-2py0A:
20.37
2j2pF-2py0A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 2py0 FIMBRIAL PROTEIN
(Pseudomonas
aeruginosa) 		4 / 4 THR A  45
VAL A  57
GLY A  74
THR A  61
 None
 1.07A 3cflA-2py0A:
undetectable		 3cflA-2py0A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 2py0 FIMBRIAL PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 SER A  39
ILE A 116
PRO A 139
SER A  31
GLY A  33
 None
 1.30A 3ijxB-2py0A:
undetectable
3ijxD-2py0A:
undetectable		 3ijxB-2py0A:
19.75
3ijxD-2py0A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 2py0 FIMBRIAL PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 ILE A 116
PRO A 139
SER A  31
GLY A  33
SER A  39
 None
 1.31A 3iluB-2py0A:
undetectable
3iluE-2py0A:
undetectable		 3iluB-2py0A:
19.75
3iluE-2py0A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 2py0 FIMBRIAL PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ASN A  80
ALA A  79
LYS A  81
 None
 1.04A 3runA-2py0A:
undetectable		 3runA-2py0A:
26.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J83_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 2py0 FIMBRIAL PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 ALA A  50
GLU A  70
GLY A  74
LYS A  58
GLU A  48
 None
 1.49A 4j83A-2py0A:
undetectable		 4j83A-2py0A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_D_SAMD401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 2py0 FIMBRIAL PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 ALA A  50
GLU A  70
GLY A  74
LYS A  58
GLU A  48
 None
 1.36A 4jdsD-2py0A:
undetectable		 4jdsD-2py0A:
22.84