SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2py8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AB2_B_SNLB503_2 (MINERALOCORTICOID RECEPTOR)	2py8	HYPOTHETICAL PROTEIN RBCX (Synechocystis sp. PCC 6803)	4 / 5	LEU A 61 LEU A 57 LEU A 67 LEU A 69	None	0.89A	2ab2B-2py8A: undetectable	2ab2B-2py8A: 20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1414_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	2py8	HYPOTHETICAL PROTEIN RBCX (Synechocystis sp. PCC 6803)	4 / 8	LEU A 67 ILE A 26 LEU A 41 LEU A 60	None	0.81A	2xfhA-2py8A: undetectable	2xfhA-2py8A: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QOP_D_HQED503_1 (CATALASE)	2py8	HYPOTHETICAL PROTEIN RBCX (Synechocystis sp. PCC 6803)	5 / 9	ILE A 78 LEU A 18 GLN A 21 TYR A 17 LEU A 86	None	1.31A	4qopD-2py8A: undetectable	4qopD-2py8A: 15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V0V_A_8QPA612_1 (SERUM ALBUMIN)	2py8	HYPOTHETICAL PROTEIN RBCX (Synechocystis sp. PCC 6803)	5 / 12	LEU A 86 LEU A 14 ILE A 78 ALA A 79 GLU A 80	None	0.86A	5v0vA-2py8A: undetectable	5v0vA-2py8A: 13.04

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2AB2_B_SNLB503_2","MINERALOCORTICOID RECEPTOR","2py8","HYPOTHETICAL PROTEIN RBCX","Synechocystis sp. PCC 6803",4,"LEU A  61;LEU A  57;LEU A  67;LEU A  69","None","0.89A","2ab2B-2py8A:undetectable","2ab2B-2py8A:20.73"],["2XFH_A_CL6A1414_1","ERYTHROMYCIN B\/D C-12 HYDROXYLASE","2py8","HYPOTHETICAL PROTEIN RBCX","Synechocystis sp. PCC 6803",4,"LEU A  67;ILE A  26;LEU A  41;LEU A  60","None","0.81A","2xfhA-2py8A:undetectable","2xfhA-2py8A:20.74"],["4QOP_D_HQED503_1","CATALASE","2py8","HYPOTHETICAL PROTEIN RBCX","Synechocystis sp. PCC 6803",5,"ILE A  78;LEU A  18;GLN A  21;TYR A  17;LEU A  86","None","1.31A","4qopD-2py8A:undetectable","4qopD-2py8A:15.62"],["5V0V_A_8QPA612_1","SERUM ALBUMIN","2py8","HYPOTHETICAL PROTEIN RBCX","Synechocystis sp. PCC 6803",5,"LEU A  86;LEU A  14;ILE A  78;ALA A  79;GLU A  80","None","0.86A","5v0vA-2py8A:undetectable","5v0vA-2py8A:13.04"]]