SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2pyf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 2pyf T-CELL RECEPTOR,
BETA CHAIN
(Homo
sapiens) 		4 / 5 LEU B 108
SER B 106
LEU B  74
LEU B  11
 None
 1.25A 4n09B-2pyfB:
undetectable		 4n09B-2pyfB:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 2pyf T-CELL RECEPTOR,
BETA CHAIN
(Homo
sapiens) 		4 / 5 LEU B 108
SER B 106
LEU B  74
LEU B  11
 None
 1.25A 4n09D-2pyfB:
undetectable		 4n09D-2pyfB:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 2pyf T-CELL RECEPTOR,
BETA CHAIN
(Homo
sapiens) 		3 / 4 ARG B 239
GLY B 238
GLU B 126
 None
 0.64A 4z2dB-2pyfB:
undetectable
4z2dC-2pyfB:
undetectable		 4z2dB-2pyfB:
19.96
4z2dC-2pyfB:
21.98